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Dietary supplement

The Glutamine Unflavoured Ingredients & Drug Interactions

by DY Nutrition

Powder Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

The Glutamine Unflavoured is a dietary supplement by DY Nutrition with 2 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 342 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beta-Glucan, L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of The Glutamine Unflavoured by DY Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains two active ingredients: L-glutamine and beta-glucan. L-glutamine is an amino acid your body uses for muscle support and immune function, especially during stress or illness.

Beta-glucan is a soluble fiber derived from yeast or mushrooms that may support heart health and cholesterol levels. The product lists beta-glucan again in the inactive ingredients section, so you're getting it from both roles in the formulation.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle recovery and sports performance.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Postoperative recovery, Critical illness (trauma), Wound healing, muscle protein synthesis — and 2 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma) (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.

The evidence for L-glutamine is strongest for sickle cell disease, where it's rated effective. For HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma, the data suggests it's possibly effective — meaning there's reason to think it may help, but proof isn't solid yet.

Beta-glucan is well supported for cholesterol (dyslipidemia) and heart disease (coronary heart disease), both rated likely effective. If you're considering this product for a specific condition, talk with your doctor about whether the evidence matches your situation.

The evidence, ingredient by ingredient Glutamine Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated when taken by mouth, but it can cause gastrointestinal side effects including bloating, gas, diarrhea, constipation, nausea, and vomiting — especially at higher doses. Headache, dizziness, and musculoskeletal pain have also been reported.

If you have kidney or liver disease, use it only under medical supervision. The safety data in pregnancy and lactation is rated likely safe for L-glutamine.

Beta-glucan from food is generally well tolerated; concentrated supplements have less safety history, so use caution. There's limited research on beta-glucan supplements during breastfeeding.

In rare cases, high-dose beta-glucan has caused temporary liver enzyme elevations and skin reactions when applied topically.

Side effects, ingredient by ingredient Glutamine Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Glutamine, Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications; immunosuppressants / transplant drugs.
  • For scale: 342 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you're on anticonvulsant drugs (seizure medications) — L-glutamine may theoretically reduce their effectiveness, though this hasn't been seen in humans yet. Also double-check if you take blood pressure medications or immunosuppressants, since beta-glucan may strengthen their effects or interfere with them.

Anyone on medication should run their specific drugs through the checker below.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you're dealing with sickle cell disease or recovering from surgery or critical illness, though the evidence for those last two is preliminary. If you take seizure medications, blood pressure drugs, or immunosuppressants, you'll need to check with your doctor or pharmacist before starting — the interactions are theoretical but documented.

Gastrointestinal side effects are common, especially at higher doses, and people with kidney or liver disease should get medical guidance first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about The Glutamine Unflavoured, straight from the product label.

Brand DY Nutrition
Barcode (UPC) 5949106122382
Net contents 300 Gram(s)
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 241762
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for The Glutamine Unflavoured by DY Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4.5 Gram(s)
Maximum serving Sizes:
4.5 Gram(s)
Servings per container
66
UPC/BARCODE
5949106122382
IngredientAmount% DV
L-Glutamine4500 mg--
Beta-Glucan45 mg--

Other ingredients: Beta-Glucan

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

The Glutamine. Food supplement. Supplementing the diet with L-Glutamine and Beta-Glucan is recommended for physically active people and athletes.

4500 mg L-Glutamine 45 mg Beta-Glucan per serving

Suggested/Recommended/Usage/Directions

Recommended use: Mix 1 scoop of powder (~4.5 g) with 250 mL of water. Drink 1 serving immediately after workout.

Precautions

Warnings: Do not use if you are allergic to any of the product compounds.

Do not exceed the recommended daily dose.

Food supplements should not be used as a substitute for a varied diet.

Do not use if pregnant or nursing.

Keep out of reach of young children.

Allergen information: Made in a facility that uses milk, soy, egg and nuts.

General Statements

1 Pete Dorian Yates 6x Mr. Olympia ShadowLine

Best before end, batch number (see on the bottom of the container).

Facebook/DorianYatesNutrition Instagram/dynutrition Youtube/DorianYatesNutrition Twitter/DYNutrition

FDA Statement of Identity

Food Supplement

Formulation

Ultimate muscle defender

Storage

Store in a dry and cool place. Protect from direct sunlight. After opening, do not store the product for more than 6 months.

See for yourself

The Glutamine Unflavoured by DY Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in The Glutamine Unflavoured by DY Nutrition

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size4.5 Gram(s) Dosage formPowder Servings per container66 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
4500 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Beta-Glucan

Interacts with
293 drugs
45 mg per serving

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly low...

Beta-Glucan monograph & interactions

Other (inactive) ingredients: Beta-Glucan. These complete the product’s ingredient list but are not active constituents.

Interaction report

The Glutamine Unflavoured by DY Nutrition Drug Interactions

Want to check YOUR meds against The Glutamine Unflavoured?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
342Drugs
342 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in The Glutamine Unflavoured with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Beta-Glucan2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for The Glutamine Unflavoured, from the product label.

DY Nutrition

See all DY Nutrition products
Name
DY Nutrition Global LTD.
Street Address
71-75 Shelton Street
City
Covent Garden
State
London
ZipCode
WC2H 9JQ
Web Address
www.dynutrition.com
Pharmacist Counseling Corner

The Glutamine Unflavoured by DY Nutrition: Common Questions

Does The Glutamine Unflavoured by DY Nutrition interact with any medications?
Yes. Based on its ingredients, The Glutamine Unflavoured has a known interaction with 342 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
The Glutamine Unflavoured contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
L-glutamine is rated likely safe in pregnancy. For breastfeeding, the safety data says to avoid supplement doses unless your doctor recommends them. Beta-glucan has no safety rating on file for pregnancy or lactation — there isn't enough research to know either way. Talk with your doctor or pharmacist before taking this while breastfeeding.
What side effects should I expect?
Gastrointestinal side effects are most common: bloating, gas, constipation, diarrhea, nausea, and vomiting. Headache, dizziness, and muscle pain have been reported with L-glutamine. These tend to happen more at higher doses, and some can improve if you reduce the amount. Let your doctor know if they don't settle down.
Will this help my cholesterol or heart health?
Beta-glucan is likely effective for both high cholesterol (dyslipidemia) and coronary heart disease according to the evidence we have. That's the strongest rated benefit in this product. It's not a replacement for other heart treatments your doctor recommends, but it may be a useful addition — ask your doctor if it fits your plan.
Is this safe if I have kidney or liver disease?
L-glutamine should only be used under medical supervision if you have kidney or liver disease. Talk with your doctor before starting this product if either applies to you.
Why is beta-glucan listed twice on the label?
Beta-glucan appears as an active ingredient and again in the inactive (other) ingredients section. This means it's playing both roles in the formulation — contributing to the product's intended effects and also serving as part of the base.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if The Glutamine Unflavoured is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

The Glutamine Unflavoured label
Sources

Sources & How We Checked

The Glutamine Unflavoured's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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