Time Female Libido Formula Ingredients & Drug Interactions
by Prime
What is this page for?
First and foremost: checking Time Female Libido Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Time Female Libido Formula is a dietary supplement by Prime with 5 active ingredients. Its ingredients are commonly taken for skin conditions like eczema, anemia related to kidney disease, allergy and inflammation support.Based on those ingredients, 1,489 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Sensoril, Pueraria mirifica extract, Velvet Bean extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Time Female Libido Formula by Prime
Ask about any prescription or over-the-counter medication and we check it for interactions with Time Female Libido Formula by Prime — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Time Female Libido Formula by Prime
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Prime Time Female Libido Formula contains five active ingredients. L-histidine is an amino acid; damiana powder is a traditional herbal ingredient; velvet bean extract (from a plant also called cowhage) supplies levodopa, a compound similar to a medication used in Parkinson's disease; Sensoril is a standardized extract of ashwagandha, an adaptogenic herb; and Pueraria mirifica extract (kudzu) is a plant extract with isoflavone compounds.
The product also contains inactive ingredients (fillers and binders) including dicalcium phosphate, croscarmellose sodium, microcrystalline cellulose, magnesium stearate, silicon dioxide, and pharmaceutical glaze.
Does it work?
Moderate evidence
The evidence for this product's active ingredients is mixed. Ashwagandha (Sensoril) is rated possibly effective for insomnia, anxiety, and stress.
For the other ingredients—L-histidine, damiana, velvet bean extract, and kudzu—the data we hold shows insufficient reliable evidence to rate their effectiveness for sexual dysfunction or the conditions this product targets. L-histidine does show possibly effective evidence for cholera, but that's outside this product's intended use.
How safe is it?
Well-documented data
L-histidine is likely safe in food amounts, but the safety of higher supplement doses hasn't been well established, so caution is advised. Damiana is likely fine in food or tea amounts, but human safety data are limited.
Velvet bean extract contains levodopa and should be used carefully with professional guidance; it may cause diarrhea, flatulence, dry mouth, nausea, vomiting, headaches, and rarely insomnia. Ashwagandha is generally well tolerated short-term in healthy adults, though long-term safety data are limited; gastrointestinal upset, nausea, and drowsiness can occur, and rare serious adverse effects (liver problems) have been reported.
Kudzu is generally well tolerated in short-term studies, with reported side effects including nausea, indigestion, bloating, and dizziness, though these didn't occur more often than placebo.
Meds to double-check
Major interaction found
Before taking this product, double-check these medication types with your pharmacist: methyldopa and other blood pressure medications (Major risk with velvet bean extract), MAOIs and other antidepressants like tricyclics (Major risk), levodopa for Parkinson's disease (Major risk), blood thinners and antiplatelet drugs, antidiabetes medications, blood pressure drugs, benzodiazepines, antipsychotics, thyroid hormone, estrogen therapy, immunosuppressants, methotrexate, tamoxifen, drugs that stress the liver, and any anesthetics you might receive.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
If you take any blood pressure medications, antidepressants (especially MAOIs or tricyclics), antidiabetes drugs, blood thinners, or estrogen therapy, you need to check this product's ingredients against your medications before starting—some interactions are serious. Even if you're not on those, run your full medication list through the checker below.
Talk to your pharmacist or doctor about whether this product is right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Time Female Libido Formula, straight from the product label.
| Brand | Prime |
|---|---|
| Barcode (UPC) | 848570001276 |
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Jun 24, 2019 |
| DSLD ID | 204034 |
| Product type | Botanical With Nutrients |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult Female (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Time Female Libido Formula by Prime, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Histidine | 500 mg | -- |
| Damiana powder | 200 mg | -- |
| Velvet Bean extract | 250 mg | -- |
| Sensoril | 250 mg | -- |
| Pueraria mirifica extract | 50 mg | -- |
Other ingredients: Dicalcium Phosphate, Croscarmellose Sodium, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, Pharmaceutical Glaze
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Anti-aging nutraceticals
FDA Statement of Identity
Dietary Supplement
Formula
Prime Time Female Libido Formula supports sexual interest, promotes normal sexual climax and may help promote normal vaginal wetness.
Suggested/Recommended/Usage/Directions
Directions for use: Adult females take 2 tablets daily.
Precautions
Warning: If you are currently taking monoamine oxidase inhibitors (MAOI), Methyldopa, antiplatelet/anticoagulant drugs or antipsychotic drugs, you should consult your healthcare provider before using this product.
Women with a history of estrogen-sensitive cancers should not take this product.
Take this supplement separately from prescription drugs. If currently you are using any prescription drugs or have an ongoing medical condition, consult your healthcare provider before using this product. Women who are pregnant or breastfeeding should not use this product.
Men and children should not use this product.
Men and children should not use this product. Keep out of the reach of children.
Do not purchase if safety seal is broken or missing.
Storage
Protect from heat, light and moisture. Store at 15-30(0)C (59-86(0)F).
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
Sensoril is a registered trademark of NutraGenesis, LLC, and is protected under U.S. patent number 6,713,092.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Time Female Libido Formula by Prime label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Time Female Libido Formula by Prime
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Histidine
No knowninteractions
Histidine is an essential amino acid your body needs to build proteins and to make compounds like histamine and carnosine. Most people get enough from...
L-Histidine monograph & interactionsDamiana powder
Interacts with86 drugs
Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is...
Damiana powder monograph & interactionsVelvet Bean extract
Interacts with193 drugs
Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied...
Velvet Bean extract monograph & interactionsSensoril
Interacts with1,372 drugs
Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evid...
Sensoril monograph & interactionsPueraria mirifica extract
Interacts with584 drugs
Kudzu is a fast-growing vine whose root has long been used in traditional Chinese medicine and is now studied mostly for reducing alcohol intake. Earl...
Pueraria mirifica extract monograph & interactionsOther (inactive) ingredients: Dicalcium Phosphate, Croscarmellose Sodium, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, Pharmaceutical Glaze. These complete the product’s ingredient list but are not active constituents.
Time Female Libido Formula by Prime Drug Interactions
HelloPharmacist Interaction Report
Prime Time Female Libido Formula contains five active ingredients, and several of them interact with medications—some quite seriously.
The most concerning is velvet bean extract (cowhage), which contains levodopa and carries Major-severity interactions with three drug types: methyldopa (a blood pressure medication), monoamine oxidase inhibitors or MAOIs (a class of antidepressants), and levodopa itself (used for Parkinson's disease). These interactions can cause dangerous drops in blood pressure, a hypertensive crisis (sudden dangerous spike), or worsening levodopa side effects.
Read the full breakdown — every affected drug type, severity by severity
Velvet bean extract also has Moderate-severity interactions with antidiabetes drugs (raising the risk of low blood sugar), antipsychotic medications (potentially reducing their effectiveness), tricyclic antidepressants or TCAs (another antidepressant class), certain anesthetics, and guanethidine (another blood pressure drug). Ashwagandha (Sensoril) carries Moderate interactions with CNS depressants (sedatives and similar drugs), blood pressure medications, immunosuppressants, benzodiazepines, antidiabetes drugs, thyroid hormone, and drugs that stress the liver, plus a Minor interaction with certain CYP1A2 substrates.
Kudzu (Pueraria mirifica) has Moderate interactions with drugs that stress the liver, estrogens, blood thinners, caffeine, methotrexate, and tamoxifen, and a Minor interaction with antidiabetes drugs. Damiana carries a Moderate interaction with antidiabetes drugs.
Although L-histidine was checked, no interactions are documented in our data. Altogether, these interactions span 1,468 individual medications.
Before you start this product, please use the medication checker on this page to verify your specific prescriptions.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Time Female Libido Formula?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Time Female Libido Formula interact with 1,489 drugs. Click any drug to see the details.
4 of the 5 ingredients in Time Female Libido Formula interact with drugs. Each result below shows which ingredient is responsible. Sensoril Pueraria mirifica extract Velvet Bean extract Damiana powder
AmphetamineAdensys XR-ODT, Adzenys ER, Dyanavel XR, Mydayis
How Amphetamine interacts with Time Female Libido Formula — through 1 ingredient. Tap an ingredient for the detail:
Velvet Bean ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean Extract + Amphetamine interactionBenserazide, LevodopaMadopar, Prolopa
How Benserazide, Levodopa interacts with Time Female Libido Formula — through 1 ingredient. Tap an ingredient for the detail:
Velvet Bean ExtractLevodopa Major
Interaction Summary
Concomitant use can increase the risk of levodopa-related adverse effects.
Read the full Velvet Bean Extract + Benserazide, Levodopa interactionCarbidopa, LevodopaDhivy, Rytary, Sinemet, Sinemet CR
How Carbidopa, Levodopa interacts with Time Female Libido Formula — through 1 ingredient. Tap an ingredient for the detail:
Velvet Bean ExtractLevodopa Major
Interaction Summary
Concomitant use can increase the risk of levodopa-related adverse effects.
Read the full Velvet Bean Extract + Carbidopa, Levodopa interactionCarbidopa, Levodopa, EntacaponeStalevo
How Carbidopa, Levodopa, Entacapone interacts with Time Female Libido Formula — through 1 ingredient. Tap an ingredient for the detail:
Velvet Bean ExtractLevodopa Major
Interaction Summary
Concomitant use can increase the risk of levodopa-related adverse effects.
Read the full Velvet Bean Extract + Carbidopa, Levodopa, Entacapone interactionChlorothiazide, MethyldopaAldochlor, Aldoclor 150, Aldoclor 250
How Chlorothiazide, Methyldopa interacts with Time Female Libido Formula — through 3 ingredients. Tap an ingredient for the detail:
Velvet Bean ExtractMethyldopa (aldomet) Major
Interaction Summary
Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Read the full Velvet Bean Extract + Chlorothiazide, Methyldopa interactionSensorilAntihypertensive Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Sensoril + Chlorothiazide, Methyldopa interactionPueraria Mirifica ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Mirifica Extract + Chlorothiazide, Methyldopa interactionHydrochlorothiazide, MethyldopaAldoril 15, Aldoril 25, Aldoril D30, Methazide
How Hydrochlorothiazide, Methyldopa interacts with Time Female Libido Formula — through 3 ingredients. Tap an ingredient for the detail:
Velvet Bean ExtractMethyldopa (aldomet) Major
Interaction Summary
Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Read the full Velvet Bean Extract + Hydrochlorothiazide, Methyldopa interactionPueraria Mirifica ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Mirifica Extract + Hydrochlorothiazide, Methyldopa interactionSensorilAntihypertensive Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Sensoril + Hydrochlorothiazide, Methyldopa interactionIsocarboxazidMarplan
How Isocarboxazid interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
Velvet Bean ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean Extract + Isocarboxazid interactionSensorilSerotonergic Drugs Minor
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Sensoril + Isocarboxazid interactionLevodopaInbrija, Larodopa
How Levodopa interacts with Time Female Libido Formula — through 1 ingredient. Tap an ingredient for the detail:
Velvet Bean ExtractLevodopa Major
Interaction Summary
Concomitant use can increase the risk of levodopa-related adverse effects.
Read the full Velvet Bean Extract + Levodopa interactionLevodopa, CarbidopaDuodopa
How Levodopa, Carbidopa interacts with Time Female Libido Formula — through 1 ingredient. Tap an ingredient for the detail:
Velvet Bean ExtractLevodopa Major
Interaction Summary
Concomitant use can increase the risk of levodopa-related adverse effects.
Read the full Velvet Bean Extract + Levodopa, Carbidopa interactionMethyldopaAldomet, Methyldopa
How Methyldopa interacts with Time Female Libido Formula — through 3 ingredients. Tap an ingredient for the detail:
Velvet Bean ExtractMethyldopa (aldomet) Major
Interaction Summary
Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Read the full Velvet Bean Extract + Methyldopa interactionSensorilAntihypertensive Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Sensoril + Methyldopa interactionPueraria Mirifica ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Mirifica Extract + Methyldopa interactionMoclobemideManerix, Moclobemide
How Moclobemide interacts with Time Female Libido Formula — through 1 ingredient. Tap an ingredient for the detail:
Velvet Bean ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean Extract + Moclobemide interactionOzanimod HydrochlorideZeposia
How Ozanimod Hydrochloride interacts with Time Female Libido Formula — through 3 ingredients. Tap an ingredient for the detail:
Velvet Bean ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean Extract + Ozanimod Hydrochloride interactionSensorilHepatotoxic Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Sensoril + Ozanimod Hydrochloride interactionPueraria Mirifica ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Mirifica Extract + Ozanimod Hydrochloride interactionPhenelzine SulfateNardil
How Phenelzine Sulfate interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
Velvet Bean ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean Extract + Phenelzine Sulfate interactionSensorilCns Depressants, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Read the full Sensoril + Phenelzine Sulfate interactionRasagilineAzilect
How Rasagiline interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
Velvet Bean ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean Extract + Rasagiline interactionSensorilSerotonergic Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Sensoril + Rasagiline interactionSafinamide MesylateXadago
How Safinamide Mesylate interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
Velvet Bean ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean Extract + Safinamide Mesylate interactionSensorilSerotonergic Drugs Minor
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Sensoril + Safinamide Mesylate interactionSelegilineCarbex, Eldepryl, Emsam, Zelapar
How Selegiline interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
Velvet Bean ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean Extract + Selegiline interactionSensorilSerotonergic Drugs Minor
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Sensoril + Selegiline interactionTranylcypromineParnate
How Tranylcypromine interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
Velvet Bean ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean Extract + Tranylcypromine interactionSensorilSerotonergic Drugs Minor
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Sensoril + Tranylcypromine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
SensorilHepatotoxic Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Sensoril + 6-mercaptopurine interactionPueraria Mirifica ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Mirifica Extract + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
SensorilHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Sensoril + Abacavir Sulfate, Dolutegravir, Lamivudine interactionPueraria Mirifica ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Mirifica Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
Pueraria Mirifica ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Mirifica Extract + Abacavir, Lamivudine interactionSensorilHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Sensoril + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Time Female Libido Formula — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Mirifica ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Pueraria Mirifica Extract + Abciximab interactionAbiraterone
How Abiraterone interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
SensorilHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Sensoril + Abiraterone interactionPueraria Mirifica ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Mirifica Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
SensorilHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Sensoril + Abiraterone Acetate interactionPueraria Mirifica ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Mirifica Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
Pueraria Mirifica ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Pueraria Mirifica Extract + Abrocitinib interactionSensorilImmunosuppressants Moderate
Interaction Summary
Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Read the full Sensoril + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Time Female Libido Formula — through 4 ingredients. Tap an ingredient for the detail:
Damiana PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Damiana Powder + Acarbose interactionPueraria Mirifica ExtractHepatotoxic Drugs, Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Mirifica Extract + Acarbose interactionSensorilAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sensoril + Acarbose interactionVelvet Bean ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of cowhage and antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Velvet Bean Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
SensorilAntihypertensive Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Sensoril + Acebutolol interactionPueraria Mirifica ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Mirifica Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Time Female Libido Formula — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Mirifica ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Pueraria Mirifica Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
Velvet Bean ExtractAntipsychotic Drugs Moderate
Interaction Summary
Theoretically, use of cowhage might decrease the clinical effects of antipsychotic drugs.
Read the full Velvet Bean Extract + Acepromazine interactionSensorilCns Depressants Moderate
Interaction Summary
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Read the full Sensoril + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
SensorilCytochrome P450 1a2 (cyp1a2) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Sensoril + Acetaminophen interactionPueraria Mirifica ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Mirifica Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Time Female Libido Formula — through 2 ingredients. Tap an ingredient for the detail:
SensorilHepatotoxic Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Sensoril + Acetaminophen, Aspirin interactionPueraria Mirifica ExtractAnticoagulant/antiplatelet Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Pueraria Mirifica Extract + Acetaminophen, Aspirin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Time Female Libido Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Sensoril
Antidiabetes Drugs
Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.
Antihypertensive Drugs
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Benzodiazepines
Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.
Cns Depressants
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.
Hepatotoxic Drugs
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.
Immunosuppressants
Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.
Thyroid Hormone
Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.
Serotonergic Drugs
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]
Pueraria mirifica extract
Anticoagulant/Antiplatelet Drugs
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Kudzu isoflavones are reported to have antiplatelet activity.
Caffeine
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
In healthy males injected with the kudzu constituent puerarin, caffeine clearance and metabolism is inhibited. This effect has been attributed to inhibition of cytochrome P450 1A2 (CYP1A2) enzyme, which is involved in caffeine metabolism. It is unclear if taking kudzu orally would have this same effect.
Estrogens
Theoretically, kudzu might alter the effects of estrogen therapy.
Some research suggests that kudzu has estrogenic effects. This may enhance or inhibit the effects of estrogen therapy.
Hepatotoxic Drugs
Theoretically, concomitant use might have additive hepatotoxic effects.
There is some concern that kudzu can adversely affect the liver.
Methotrexate (Trexall, Others)
Theoretically, taking kudzu with methotrexate might increase the risk of methotrexate toxicity.
Preclinical research suggests that kudzu extract greatly reduces the elimination and increases the toxicity of methotrexate. Kudzu might inhibit organic anion transporters (OATs) that are responsible for hepatobiliary and renal excretion of anions, similar to the interaction between methotrexate and non-steroidal anti-inflammatory drugs (NSAIDs).
Tamoxifen (Nolvadex)
Theoretically, kudzu might interfere with tamoxifen activity.
Some research suggests that kudzu may have estrogenic effects.
Antidiabetes Drugs
Theoretically, taking kudzu with antidiabetes drugs might increase the risk of hypoglycemia.
Kudzu might lower blood glucose levels and have additive effects in patients treated with antidiabetic agents. The dose of diabetes medications might need to be adjusted.
Velvet Bean extract
Levodopa
Concomitant use can increase the risk of levodopa-related adverse effects.
Cowhage contains levodopa. Some cowhage products have been standardized to contain 75-400 mg of levodopa per dose.
Methyldopa (Aldomet)
Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with methyldopa might cause additive hypotension. In addition, methyldopa may inhibit peripheral decarboxylation of levodopa and increase levodopa levels in the central nervous system; avoid using.
Monoamine Oxidase Inhibitors (Maois)
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Cowhage contains levodopa. Use of levodopa with non-selective MAOIs might cause hypertensive crisis. However, this interaction has not been reported with MAO-B selective inhibitors such as selegiline.
Anesthesia
Theoretically, concomitant use of cowhage and anesthesia might increase the risk of arrhythmias.
Cowhage contains levodopa. Use of levodopa with cyclopropane or halogenated hydrocarbon anesthesia has led to arrhythmias. Other anesthetics have not been implicated. Use other anesthetics in patients taking cowhage or tell patients to stop taking cowhage at least 2 weeks before surgery.
Antidiabetes Drugs
Theoretically, concomitant use of cowhage and antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that cowhage might have hypoglycemic effects.
Antipsychotic Drugs
Theoretically, use of cowhage might decrease the clinical effects of antipsychotic drugs.
Cowhage contains levodopa. Use of levodopa might counteract the antidopaminergic effects of antipsychotic medications.
Guanethidine (Ismelin)
Theoretically, concomitant use of cowhage and guanethidine might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with guanethidine might cause additive hypotension; avoid using.
Tricyclic Antidepressants (Tcas)
Theoretically, use of TCAs might reduce the levels and clinical effects of cowhage.
Cowhage contains levodopa. Use of TCAs might reduce the absorption of levodopa. Some case reports describe patients that developed hypertension and dyskinesia when taking both levodopa and TCAs.
Damiana powder
Antidiabetes Drugs
Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that taking damiana lowers blood glucose level.
Brand information
Manufacturer and brand details for Time Female Libido Formula, from the product label.
Prime
See all Prime products- Name
- Market America, Inc.
- Street Address
- 1302 Pleasant Ridge Road
- City
- Greensboro
- State
- NC
- ZipCode
- 27409
Time Female Libido Formula by Prime: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Time Female Libido Formula’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Histidine
Histidine is an essential amino acid your body needs to build proteins and to make compounds like histamine and carnosine. Most people get enough from a normal diet, and good-quality researc...
Read the full Histidine monograph → Herb & supplement monographDamiana
Interacts with 86 drugsDamiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is generally well tolerated in the small am...
Read the full Damiana monograph → Herb & supplement monographCowhage
Interacts with 193 drugsCowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied for Parkinson's disease symptoms and ma...
Read the full Cowhage monograph → Herb & supplement monographAshwagandha
Interacts with 1,372 drugsAshwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evidence is still limited. It is generally w...
Read the full Ashwagandha monograph → Herb & supplement monographKudzu
Interacts with 584 drugsKudzu is a fast-growing vine whose root has long been used in traditional Chinese medicine and is now studied mostly for reducing alcohol intake. Early research is promising for cutting back...
Read the full Kudzu monograph →Sources & How We Checked
Time Female Libido Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 70 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Histidine 3 references
Damiana 2 references
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Cowhage 12 references
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- HP-200 in Parkinson's Disease study group. An alternative medicine treatment for Parkinson's disease: Results of a multicenter clinical trial. J Alt Comp Med 1995;1:249-55. DOI
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- Prakash, D., Niranjan, A., and Tewari, S. K. Some nutritional properties of the seeds of three Mucuna species. Int.J.Food Sci.Nutr. 2001;52(1):79-82.
- Vadivel, V. and Janardhanan, K. Nutritional and antinutritional characteristics of seven South Indian wild legumes. Plant Foods Hum.Nutr 2005;60(2):69-75. PubMed
- Creapure (Creatine Monohydrate). Toxicological Datasheet. Degussa BioActives. Available at: https://www.fda.gov/ohrms/DOCKETS/.../95s-0316-rpt0154-54-Ref-50-vol112.pdf.
- Pulikkalpura H, Kurup R, Mathew PJ, Baby S. Levodopa in Mucuna pruriens and its degradation. Sci Rep 2015;5:11078. PubMed
Ashwagandha 32 references
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- Upton R, ed. Ashwagandha Root (Withania somnifera): Analytical, quality control, and therapuetic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia 2000:1-25.
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- Kulkarni RR, Patki PS, Jog VP, et al. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol 1991;33:91-5. PubMed
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- Sehgal, V. N., Verma, P., and Bhattacharya, S. N. Fixed-drug eruption caused by ashwagandha (Withania somnifera): a widely used Ayurvedic drug. Skinmed. 2012;10(1):48-49.
- Agnihotri AP, Sontakke SD, Thawani VR, Saoji A, Goswami VS. Effects of Withania somnifera in patients of schizophrenia: a randomized, double blind, placebo controlled pilot trial study. Indian J Pharmacol. 2013;45(4):417-8. PubMed
- Biswal BM, Sulaiman SA, Ismail HC, Zakaria H, Musa KI. Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients. Integr Cancer Ther. 2013;12(4):312-22.
- Sharma AK, Basu I, Singh S. Efficacy and safety of Ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial. J Altern Complement Med. 2018 Mar;24(3):243-248. PubMed
- Durg S, Bavage S, Shivaram SB. Withania somnifera (Indian ginseng) in diabetes mellitus: A systematic review and meta-analysis of scientific evidence from experimental research to clinical application. Phytother Res. 2020;34(5):1041-1059.
- Björnsson HK, Björnsson ES, Avula B, et al. Ashwagandha-induced liver injury: A case series from Iceland and the US Drug-Induced Liver Injury Network. Liver Int. 2020;40(4):825-829. PubMed
- Tharakan A, Shukla H, Benny IR, Tharakan M, George L, Koshy S. Immunomodulatory Effect of Withania somnifera (Ashwagandha) Extract-A Randomized, Double-Blind, Placebo Controlled Trial with an Open Label Extension on Healthy Participants. J Clin Med 2021;1 PubMed
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- Kamal HI, Patel K, Brdak A, Heffernan J, Ahmad N. Ashwagandha as a unique cause of thyrotoxicosis presenting with supraventricular tachycardia. Cureus. 2022 Mar 25;14(3):e23494. PubMed
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- Pusec CM, Wolsky R, Llerena C, Sura P. A Case of Supplement-Induced Hepatitis. Cureus 2022;14(10):e30433. PubMed
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- Tóth M, Benedek AE, Longerich T, Seitz HK. Ashwagandha-induced acute liver injury: A case report. Clin Case Rep 2023;11(3):e7078.
- Bokan G, Glamocanin T, Mavija Z, et al. Herb-Induced Liver Injury by Ayurvedic Ashwagandha as Assessed for Causality by the Updated RUCAM: An Emerging Cause. Pharmaceuticals (Basel) 2023;16(8):1129. PubMed
- Patel PA, Sanborn E, Then R, Williams DM. Recurrent Reversible Cerebral Vasoconstriction Syndrome: A Report of Two Cases. Cureus 2023;15(8):e42992. PubMed
- Majeed M, Nagabhushanam K, Murali A, Vishwanathan DT, Mamidala RV, Mundkur L. A Standardized Withania somniferra (Linn.) Root Extract with Piperine Alleviates the Symptoms of Anxiety and Depression by Increasing Serotonin Levels: A Double-Blind, Randomize
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- Vazirani S, Kothari A, Fujimoto J, Gomez M. Supplements Are Not a Synonym for Safe: Suspected Liver Injury From Ashwagandha. Fed Pract 2023;40(9):315-319. PubMed
- Patel M, Newell R, Hillier M, Ramalingam R. Herbal remedies as a potential cause of hypoadrenalism. Br J Hosp Med (Lond) 2024;85(6):1-4. PubMed
Kudzu 21 references
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- Akita H, Sowa J, Makiura M, et al. Maculopapular drug eruption due to the Japanese herbal medicine Kakkonto (kudzu or arrowroot decoction). Contact Dermatitis 2003;48:348-9. PubMed
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC