Interactions on record — worth a quick check against your medications. Based on 6 of 9 ingredients. Check your meds →
Dietary supplement

Veiniac Fruit Explosion Ingredients & Drug Interactions

by Anabolic Warfare

Veiniac Fruit Explosion label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Veiniac Fruit Explosion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Veiniac Fruit Explosion is a dietary supplement by Anabolic Warfare with 9 active ingredients. Its ingredients are commonly taken for exercise performance, muscle soreness and fatigue, blood flow and circulation.Based on those ingredients, 297 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are AGMass, Sodium, L-Citrulline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Veiniac Fruit Explosion by Anabolic Warfare

Ask about any prescription or over-the-counter medication and we check it for interactions with Veiniac Fruit Explosion by Anabolic Warfare — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Veiniac Fruit Explosion by Anabolic Warfare

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 9 of its 9 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Veiniac Fruit Explosion contains 9 active ingredients designed to support athletic performance and blood flow. The main ones are L-citrulline (which your body converts to arginine and may help widen blood vessels), beta-alanine (for muscle endurance during exercise), betaine anhydrous (for muscle support), sodium (for hydration), glycerol (GlycerSize, for fluid balance), agmatine (AGMass), and nitric oxide boosters (Nitrosigine, listed twice in the formula).

The powder also includes inactive ingredients like flavoring, acids, sweeteners, and flow agents.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle pump and workout performance support.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle breakdown, Muscle strength, Physical performance, muscle endurance, nitric oxide production — and 1 related terms.
  • The strongest evidence on file: Glycerol is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Beta-alanine is rated "Possibly Effective" for Athletic performance, Physical performance.
  • Also on file: L-citrulline is rated "Possibly Effective" for Athletic performance.

L-citrulline is possibly effective for athletic performance. Beta-alanine is also possibly effective for both athletic performance and physical performance.

Betaine anhydrous is effective for a condition called homocystinuria and possibly effective for elevated homocysteine, though evidence for athletic or fitness use isn't rated in our data. Glycerol is likely effective for constipation and possibly effective for athletic performance.

For agmatine, the evidence we hold isn't established — there's insufficient reliable evidence for any of the conditions listed. The same applies to Norvaline and Nitrosigine, for which we hold no effectiveness data.

The evidence, ingredient by ingredient L-citrulline Beta-alanine Betaine Anhydrous Sodium Glycerol Agmatine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-citrulline, beta-alanine, and agmatine are all generally well tolerated in healthy adults short-term, though long-term safety isn't fully studied. The most common side effects are gastrointestinal — heartburn and stomach discomfort from L-citrulline, and flushing and a tingling sensation (paresthesia) from beta-alanine, which typically starts on the scalp within 20 minutes and lasts about an hour.

Betaine can cause body odor, nausea, diarrhea, and gas. Glycerol may cause bloating, nausea, vomiting, dizziness, and headache at larger doses.

Agmatine has caused diarrhea, indigestion, and nausea in small studies. Sodium in normal dietary amounts is fine, but excessive intake can worsen blood pressure and heart strain.

None of these ingredients have adequate safety data in pregnancy or while breastfeeding — the data advises against use during those times.

Side effects, ingredient by ingredient L-citrulline Beta-alanine Betaine Anhydrous Sodium Glycerol Agmatine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 6 matched ingredients can interact with medications — L-citrulline, Sodium, Agmatine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 297 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check with your pharmacist if you take blood pressure medications (antihypertensive drugs) — L-citrulline, sodium, and agmatine can all add to their effect. Also flag diabetes medications (agmatine may lower blood sugar further), ED drugs like sildenafil (L-citrulline adds to their blood-vessel-widening action), lithium, corticosteroids, didanosine, tolvaptan, or any other sodium-containing products.

No interactions are documented for Norvaline or Nitrosigine.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Veiniac Fruit Explosion is aimed at people training hard who want to improve blood flow and muscle endurance, but it's not for everyone. If you take blood pressure medications, diabetes drugs, ED medications, lithium, or corticosteroids, you need to check this product with your doctor or pharmacist first — the ingredient interactions are real.

The product is generally well tolerated for short-term use in healthy adults, though expect possible tingling, stomach upset, or body odor. Skip it during pregnancy and breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Veiniac Fruit Explosion, straight from the product label.

Brand Anabolic Warfare
Barcode (UPC) 812575030289
Net contents 11.9 Ounce(s); 340 Gram(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 337982
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Veiniac Fruit Explosion by Anabolic Warfare, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
16 Gram(s)
Maximum serving Sizes:
16 Gram(s)
Servings per container
20
UPC/BARCODE
812575030289
IngredientAmount% DV
L-Citrulline6000 mg--
Beta-Alanine1500 mg--
Betaine Anhydrous2500 mg--
Sodium55 mg2%
Norvaline250 mg--
GlycerSize2000 mg--
Nitrosigine40 mg1%
AGMass500 mg--
Nitrosigine1200 mg--

Other ingredients: Natural & Artificial Flavors, Malic Acid, Citric Acid, Silicon Dioxide, Calcium Silicate, Sucralose, Acesulfame Potassium, Salt

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions Mix 1 scoop of Veiniac with 8-12 oz. of water, 15 minutes prior to workout.

Formula

Benefits: Veiniac is packed with over 13 g of muscle pump activators per serving to support strength and performance during workouts. 6 g Of L-Citrulline paired with 500mg of AGMass to boost nitric oxide production and increase muscle pumps. 2.5 g Of Betaine Anhydrous to improve athletic performance and support protein synthesis. 2 g Of Glycersize to support optimal muscle pumps and increased hydration.

Fruit explosion Naturally and artificially flavored

Nitrosigine Bonded Arginine Silicate

Precautions

Warning: Not intended for anyone under the age of 18. Keep out of reach of children.

If you are nursing, pregnant, taking medication or have a medical condition, consult your physician before taking this product.

Warning: Consuming this product can expose you to chemicals including lead which is known by the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov/food.

Manufactured in a facility which processes milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soybeans, and sesame.

Formulation

Ingredients in this product will clump when exposed to air and humidity. This does not affect the efficacy of the product and can still be used safely until its best by date.

Mega-dosed pump accelerator Promote Nitric Oxide Support optimal strength Increase muscle pumps

Storage

Store in a cool, dry & dark place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Inspected Facility Good Manufacturing Practice cGMP

Brand IP Statement(s)

Nitrosigine, including the Nitrosigine logo, is a trademark of Nutrition 21, LLC. Nitrosigine is patent protected. GlycerSize is a trademark of Pinnacle Ingredients Pty Ltd (Australia) AGMass is exclusively distributed by Compound Solutions.

General Statements

Facebook facebook.com/anabolicwarfare Instagram @anabolicwarfare

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Veiniac Fruit Explosion by Anabolic Warfare label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Veiniac Fruit Explosion label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Veiniac Fruit Explosion by Anabolic Warfare

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size16 Gram(s) Dosage formPowder Servings per container20 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Citrulline

Interacts with
178 drugs
6000 mg per serving

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. I...

L-Citrulline monograph & interactions

Beta-Alanine

No known
interactions
1500 mg per serving

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...

Beta-Alanine monograph & interactions

Betaine Anhydrous

No known
interactions
2500 mg per serving

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and a...

Betaine Anhydrous monograph & interactions

Sodium

Interacts with
205 drugs
55 mg per serving Form: Pink Himalayan Sea Salt

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Norvaline

250 mg per serving

GlycerSize

No known
interactions
2000 mg per serving Form: Glycerol, Powder

Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well establis...

GlycerSize monograph & interactions

Nitrosigine

40 mg per serving Form: Potassium

AGMass

Interacts with
258 drugs
500 mg per serving Form: Agmatine Sulfate

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most...

AGMass monograph & interactions

Nitrosigine

1200 mg per serving Form: Inositol-Stabilized Arginine Silicate

Other (inactive) ingredients: Natural & Artificial Flavors, Malic Acid, Citric Acid, Silicon Dioxide, Calcium Silicate, Sucralose, Acesulfame Potassium, Salt. These complete the product’s ingredient list but are not active constituents.

Interaction report

Veiniac Fruit Explosion by Anabolic Warfare Drug Interactions

Want to check YOUR meds against Veiniac Fruit Explosion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
297Drugs
297 Moderate

Ingredients driving the most interactions

AGMass 258
Sodium 205
L-Citrulline 178

Individual Drug Interactions

The ingredients in Veiniac Fruit Explosion interact with 297 drugs. Click any drug to see the details.

3 of the 9 ingredients in Veiniac Fruit Explosion interact with drugs. Each result below shows which ingredient is responsible. AGMass Sodium L-Citrulline

Each ingredient & the kinds of drugs it affects

For each ingredient in Veiniac Fruit Explosion with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

AGMass2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, agmatine might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggest that agmatine has mild hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, agmatine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that agmatine can modestly decrease heart rate and blood pressure.

Likelihood Possible Evidence D
AGMass full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

L-Citrulline2 drug types · 178 drugs

Antihypertensive Drugs

Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.

Likelihood Possible Evidence B
Phosphodiesterase-5 Inhibitors

Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
L-Citrulline full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Veiniac Fruit Explosion, from the product label.

Anabolic Warfare

See all Anabolic Warfare products
Name
Anabolic Warfare
City
Austin
State
TX
Phone Number
888-301-4002
Web Address
anabolicwarfare.com
Pharmacist Counseling Corner

Veiniac Fruit Explosion by Anabolic Warfare: Common Questions

Does Veiniac Fruit Explosion by Anabolic Warfare interact with any medications?
Yes. Based on its ingredients, Veiniac Fruit Explosion has a known interaction with 297 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Veiniac Fruit Explosion contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's the tingling I've heard about with this product?
That's from beta-alanine, which causes a dose-dependent pins-and-needles feeling (paresthesia) and skin flushing. It usually starts on your scalp about 20 minutes after you take it and spreads to most of your body, lasting roughly an hour. It's harmless but can feel intense at higher doses — at the lowest doses only about a quarter of people experience it.
Is this safe if I'm pregnant or breastfeeding?
The data advises against it. There isn't enough safety information for L-citrulline, beta-alanine, betaine, agmatine, or glycerol during pregnancy or while nursing. Talk to your doctor or midwife before using any of these.
Can I take this if I have high blood pressure?
Not without checking first. L-citrulline, sodium, and agmatine can all lower blood pressure further, and sodium itself can reduce how well your blood pressure medication works. You need to discuss this with your doctor or pharmacist before starting.
Does this actually improve athletic performance?
L-citrulline and beta-alanine are both possibly effective for athletic performance, so there's some evidence they help. Glycerol is also possibly effective for athletic performance. The others in the formula either have limited evidence or insufficient data in our system.
What are the most common side effects?
The tingling and flushing from beta-alanine is the most notable. Beyond that, you might experience stomach upset, heartburn, nausea, diarrhea, or gas from various ingredients. Body odor has been reported with betaine. Most side effects are mild and go away on their own.
Does sodium in this powder affect my blood pressure medication?
Yes — theoretically, a high sodium intake can reduce how well blood pressure drugs work. If you're on a blood pressure medication, your prescriber should know you're taking this product, especially if you're using it regularly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Veiniac Fruit Explosion is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Veiniac Fruit Explosion label
Go deeper

The Full Monographs Behind Veiniac Fruit Explosion’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

L-citrulline

Interacts with 178 drugs

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. It is popular for exercise performance an...

Read the full L-citrulline monograph → Herb & supplement monograph

Beta-alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...

Read the full Beta-alanine monograph → Herb & supplement monograph

Betaine Anhydrous

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and as a prescription medicine for a rare gen...

Read the full Betaine Anhydrous monograph → Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Glycerol

Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well established as a laxative and a skin and eye moi...

Read the full Glycerol monograph → Herb & supplement monograph

Agmatine

Interacts with 258 drugs

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most of its claimed benefits is limited and...

Read the full Agmatine monograph →
Sources

Sources & How We Checked

Veiniac Fruit Explosion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 81 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

L-citrulline 8 references
  1. Cheng JW, Balwin SN. L-arginine in the management of cardiovascular diseases. Ann Pharmacother 2001;35:755-64. PubMed
  2. Schwedhelm E, Maas R, Freese R, et al. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol 2008;65:51-9. PubMed
  3. Romero MJ, Platt DH, Caldwell RB, Caldwell RW. Therapeutic use of citrulline in cardiovascular disease. Cardiovasc Drug Rev 2006;24:275-90. PubMed
  4. Balderas-Munoz K, Castillo-Martínez L, Orea-Tejeda A, et al. Improvement of ventricular function in systolic heart failure patients with oral L-citrulline supplementation. Cardiol J 2012;19:612-7. PubMed
  5. Sharif Kashani B, Tahmaseb Pour P, Malekmohammad M, et al. Oral l-citrulline malate in patients with idiopathic pulmonary arterial hypertension and Eisenmenger Syndrome: a clinical trial. J Cardiol 2014;64:231-5. PubMed
  6. Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res 2010;24:1215-22. PubMed
  7. Mirenayat MS, Moradi S, Mohammadi H, Rouhani MH. Effect of L-citrulline supplementation on blood pressure: a systematic review and meta-analysis of clinical trials. Curr Hypertens Rep. 2018;20(11):98. PubMed
  8. Xu Z, Liu C, Liu S, Zhou Z. Comparison of efficacy and safety of daily oral L-arginine and PDE5Is alone or combination in treating erectile dysfunction: A systematic review and meta-analysis of randomised controlled trials. Andrologia. 2021:e14007. PubMed

See these in context on the L-citrulline monograph →

Beta-alanine 13 references
  1. Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006;30:279-89.
  2. Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
  3. Bellinger PM, Minahan CL. The effect of ß-alanine supplementation on cycling time trials of different length. Eur J Sport Sci 2016;16(7):829-36.
  4. Chung W, Shaw G, Anderson ME, et al. Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers. Nutrients 2012;4(10):1441-53. PubMed
  5. Glenn JM, Gray M, Stewart R, et al. Incremental effects of 28 days of beta-alanine supplementation on high-intensity cycling performance and blood lactate in masters female cyclists. Amino Acids 2015;47(12):2593-600. PubMed
  6. Gross M, Bieri K, Hoppeler H, Norman B, Vogt M. Beta-alanine supplementation improves jumping power and affects severe-intensity performance in professional alpine skiers. Int J Sport Nutr Exerc Metab 2014;24(6):665-73. PubMed
  7. Howe ST, Bellinger PM, Driller MW, Shing CM, Fell JW. The effect of beta-alanine supplementation on isokinetic force and cycling performance in highly trained cyclists. Int J Sport Nutr Exerc Metab 2013;23(6):562-70. PubMed
  8. Sweeney KM, Wright GA, Glenn Brice A, Doberstein ST. The effect of beta-alanine supplementation on power performance during repeated sprint activity. J Strength Cond Res 2010;24(1):79-87.
  9. Décombaz J, Beaumont M, Vuichoud J, Bouisset F, Stellingwerff T. Effect of slow-release ß-alanine tablets on absorption kinetics and paresthesia. Amino Acids 2012;43(1):67-76. Erratum in: Amino Acids 2013;45(4):1015.
  10. Stellingwerff T, Anwander H, Egger A, et al. Effect of two ß-alanine dosing protocols on muscle carnosine synthesis and washout. Amino Acids 2012;42(6):2461-72. PubMed
  11. da Silva RP, de Oliveira LF, Saunders B, et al. Effects of ß-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids. 2019;51(1):83-96. PubMed
  12. Varanoske AN, Hoffman JR, Church DD, et al. Comparison of sustained-release and rapid-release ß-alanine formulations on changes in skeletal muscle carnosine and histidine content and isometric performance following a muscle-damaging protocol. Amino Acids. PubMed
  13. Perim P, Gobbi N, Duarte B, et al. Beta-alanine did not improve high-intensity performance throughout simulated road cycling. Eur J Sport Sci 2021. PubMed

See these in context on the Beta-alanine monograph →

Betaine Anhydrous 11 references
  1. Cystadane (betaine anhydrous for oral solution) Package insert. Orphan Medical, Inc. Minnetonka, MN. November 2005.
  2. Abdelmalek MF, Angulo P, Jorgensen RA, et al. Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Am J Gastroenterol 2001;96:2711-7.. PubMed
  3. Schwab U, Torronen A, Toppinen L, et al. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr 2002;76:961-7. PubMed
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See these in context on the Betaine Anhydrous monograph →

Sodium 38 references
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See these in context on the Sodium monograph →

Glycerol 8 references
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See these in context on the Glycerol monograph →

Agmatine 3 references
  1. Piletz JE, Aricioglu F, Cheng JT, et al. Agmatine: clinical applications after 100 years in translation. Drug Discov Today 2013;18(17-18):880-93. PubMed
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See these in context on the Agmatine monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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