Interactions on record — worth a quick check against your medications. Based on 2 of 6 ingredients. Check your meds →
Dietary supplement

Women's Total Care Probiotic 50 Billion Ingredients & Drug Interactions

by Spring Valley

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Women's Total Care Probiotic 50 Billion is a dietary supplement by Spring Valley with 6 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus, Lactobacillus gasseri. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Women's Total Care Probiotic 50 Billion by Spring Valley

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Proprietary Probiotic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

This product contains 6 active probiotic ingredients — live beneficial bacteria intended to support digestive and women's health. The two we have data for are Lactobacillus acidophilus and Lactobacillus gasseri; the other four are Lactobacillus rhamnosus, Bifidobacterium animalis lactis, Lactobacillus plantarum, and Lactobacillus casei.

The inactive ingredients are rice dextrin, a vegetarian capsule, and magnesium stearate.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support vaginal and urinary tract health.
  • We looked for evidence on: Bacterial vaginosis, Urinary tract infections (UTIs), Vaginal candidiasis, Vulvovaginitis, Cystitis.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Bacterial vaginosis (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Urinary tract infections (UTIs), Vaginal candidiasis.
  • Also on file: Lactobacillus Gasseri is rated "Insufficient Reliable Evidence To Rate" for Bacterial vaginosis.

For Lactobacillus acidophilus, the evidence suggests possible effectiveness for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis. It's rated possibly ineffective for atopic disease (allergic conditions), and there isn't enough reliable evidence to rate it for acute respiratory distress syndrome (ARDS).

For Lactobacillus gasseri, we don't have enough reliable evidence to rate it for any of the conditions our data cover — including hay fever, aspirin-related stomach damage, asthma, bacterial vaginosis, common cold, or diarrhea. We hold no effectiveness data for the other four ingredients in this blend.

The evidence, ingredient by ingredient Lactobacillus Acidophilus Lactobacillus Gasseri

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children, though you should check with your doctor before use. Gastrointestinal side effects like stomach discomfort, bloating, flatulence, and diarrhea can occur when taking it with other probiotics, but these are uncommon.

In rare cases, live probiotic organisms can translocate (move) from the gut to other parts of the body and cause serious infections like sepsis or endocarditis, though this is thought to happen mainly in people whose natural barriers are already compromised. Lactobacillus gasseri is generally well tolerated, but safety data are limited; check with your doctor before using.

The same serious infection risk applies — it's rare but documented. No pregnancy or breastfeeding safety data are provided in our records for either ingredient.

Side effects, ingredient by ingredient Lactobacillus Acidophilus Lactobacillus Gasseri

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Lactobacillus Acidophilus, Lactobacillus Gasseri.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Antibiotic drugs are the documented interaction — taking them at the same time as this product may reduce how well the probiotics work. Separate your antibiotics from this supplement by several hours, and ask your pharmacist or doctor for the best timing.

We could not check four of the six bacterial strains for interactions, so use the medication checker below for your complete list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This probiotic may help with IBS, antibiotic-associated diarrhea, and bacterial vaginosis if you take Lactobacillus acidophilus. If you're on antibiotics, don't take this at the same time — space them several hours apart.

Anyone with a weak immune system or serious illness should talk to their doctor first. Check your medications with the tool on this page before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Women's Total Care Probiotic 50 Billion, straight from the product label.

Brand Spring Valley
Barcode (UPC) 68113115675
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jun 25, 2018
DSLD ID 178351
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult Female (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Women's Total Care Probiotic 50 Billion by Spring Valley, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
68113115675
IngredientAmount% DV
Proprietary Probiotic Blend0 NP--
Lactobacillus rhamnosus0 NP--
Lactobacillus acidophilus0 NP--
Bifidobacterium animalis lactis0 NP--
Lactobacillus plantarum0 NP--
Lactobacillus casei0 NP--
Lactobacillus gasseri0 NP--

Other ingredients: Rice Dextrin, Vegetarian Capsule, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formula

Spring Valley Women's Total Care Probiotic supplement contains 7 specific women-friendly strains of Bifidobacteria and Lactobacilli to: Support vaginal and urinary tract health by promoting healthy pH levels Promote regularity and healthy digestion Provide support for a healthy immune system

Formulated for Women to help support vaginal health and urinary tract health

Formulation

This unique formulation is also designed to maximize its benefit to you by being: Suitable for a Vegan lifestyle Gluten-free Free of major allergens (including eggs, soy, dairy, nut, peanut, wheat, fish, shellfish) Acid and bile resistant strains Blister sealed capsules for maximum freshness

This unique formulation is also designed to maximize its benefit to you by being: Suitable for a Vegan lifestyle Gluten-free Free of major allergens (including eggs, soy, dairy, nut, peanut, wheat, fish, shellfish) Acid and bile resistant strains Blister sealed capsules for maximum freshness

No gluten, dairy, soy, peanut, sweetener, preservatives.

General Statements

What Are Probiotics? The human digestive system is home to trillions of bacteria that perform many helpful functions. The healthy balance of good bacteria can be disrupted by diet, travel or stress. Probiotics are beneficial bacteria that can help replenish and support a healthy balance. Probiotic strains are different types of bacteria, each of which may provide different health benefits.

Please recycle

Women's Total Care Probiotic 50 billion active cultures per capsule 7 strains Digestive health Promotes healthy digestion and immune systems.

Delayed release capsules for targeted release Actual size

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Warning: Consult your physician before using this product if you are pregnant, nursing, trying to conceive, taking medication or have a medical condition.

Keep out of reach of children.

Do not use if seal is broken.

Storage

Store at 73(0)F or below. Do not expose to excessive heat or moisture. No refrigeration required.

Brand IP Statement(s)

Quality Guaranteed Spring Valley products are produced under strict quality guidelines. If you are unhappy with this product, we’ll replace it or refund your money.

General

548643

Suggested/Recommended/Usage/Directions

Suggested Use: For adults, take one (1) capsule daily at mealtime.

See for yourself

Women's Total Care Probiotic 50 Billion by Spring Valley label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Women's Total Care Probiotic 50 Billion by Spring Valley

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Probiotic Blend

0 NP per serving

Other (inactive) ingredients: Rice Dextrin, Vegetarian Capsule, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Women's Total Care Probiotic 50 Billion by Spring Valley Drug Interactions

Want to check YOUR meds against Women's Total Care Probiotic 50 Billion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Women's Total Care Probiotic 50 Billion with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D

Lactobacillus gasseri1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L. gasseri.
Lactobacillus gasseri preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. gasseri preparations by at least two hours.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Women's Total Care Probiotic 50 Billion, from the product label.

Spring Valley

See all Spring Valley products
Name
Wal-Mart Stores, Inc.
City
Bentonville
State
AR
ZipCode
72716
Phone Number
1-866-251-1662
Web Address
Walmart.com/springvalley
Pharmacist Counseling Corner

Women's Total Care Probiotic 50 Billion by Spring Valley: Common Questions

Does Women's Total Care Probiotic 50 Billion by Spring Valley interact with any medications?
Yes. Based on its ingredients, Women's Total Care Probiotic 50 Billion has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Women's Total Care Probiotic 50 Billion contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm on antibiotics?
Not at the same time — antibiotics can kill the live bacteria in this supplement and make it less effective. Ask your pharmacist how many hours to space them apart. Your doctor or pharmacist can help you figure out the best timing.
What are the side effects?
Stomach discomfort, bloating, flatulence, and diarrhea can happen when taking probiotics, but they're uncommon. Very rarely, the live organisms can cause serious infections, but this is thought to happen mainly in people with weakened immunity or serious illness.
Is this safe if I'm pregnant or breastfeeding?
We don't have pregnancy or breastfeeding safety data on file for the ingredients in this product. Talk with your doctor or pharmacist before starting it if you're pregnant, planning to become pregnant, or breastfeeding.
Does this actually work for IBS or bacterial vaginosis?
Lactobacillus acidophilus, one of the strains in here, is rated possibly effective for both IBS and bacterial vaginosis. That means there's some evidence it may help, but it's not guaranteed. We don't have enough data on the other four strains to rate them.
What exactly is in this?
Six live probiotic bacteria strains — Lactobacillus acidophilus, Lactobacillus gasseri, Lactobacillus rhamnosus, Bifidobacterium animalis lactis, Lactobacillus plantarum, and Lactobacillus casei — plus rice dextrin, a vegetarian capsule, and magnesium stearate as inactive ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Women's Total Care Probiotic 50 Billion is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Women's Total Care Probiotic 50 Billion label
Sources

Sources & How We Checked

Women's Total Care Probiotic 50 Billion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 27 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Lactobacillus Gasseri 12 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Ramachandran L, Dontaraju VS, Patel K. Lactobacillus-associated spontaneous bacterial peritonitis in a liver cirrhosis patient on probiotics. Cureus. 2020;12(12):e11896. PubMed
  3. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  4. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  5. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  6. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  7. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  8. Ramos-Coria D, Canto-Losa J, Carrillo-Vázquez D, Carbajal-Morelos L, Estrada-León R, Corona-Rodarte E. Lactobacillus gasseri liver abscess and bacteremia: a case report. BMC Infect Dis 2021;21(1):518. PubMed
  9. Elikowski W, Malek-Elikowska M, Lisiecka M, Bodora A, Wisniewska K, Oko-Sarnowska Z. Lactobacillus gasseri endocarditis on the aortic valve bioprosthesis - a case report. Pol Merkur Lekarski 2017;43(257):220-223.
  10. Esquibel A, Dababneh AS, Palraj BR. Lactobacillus gasseri causing bilateral empyema. Case Rep Infect Dis 2017;2017:4895619.
  11. Tleyjeh IM, Routh J, Qutub MO, Lischer G, Liang KV, Baddour LM. Lactobacillus gasseri causing Fournier's gangrene. Scand J Infect Dis 2004;36(6-7):501-3. PubMed
  12. Dickgiesser U, Weiss N, Fritsche D. Lactobacillus gasseri as the cause of septic urinary infection. Infection 1984;12(1):14-6. PubMed

See these in context on the Lactobacillus Gasseri monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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