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Dietary supplement

Wormwood Ingredients & Drug Interactions

by Energique

Wormwood label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Wormwood against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Wormwood is a dietary supplement by Energique with 1 active ingredient. Its ingredients are commonly taken for digestive upset and poor appetite, intestinal parasites, crohn's disease symptoms.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Wormwood. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Wormwood by Energique

Ask about any prescription or over-the-counter medication and we check it for interactions with Wormwood by Energique — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Wormwood by Energique

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1.50 mL) without saying how much of each component you get.

This liquid contains one active ingredient: wormwood. The product also includes water and ethanol as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Wormwood product and its label doesn't state a use — see Wormwood's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for wormwood isn't established in the data we hold. For biliary disorders, Crohn disease, depression, dyspepsia, and osteoarthritis, there is insufficient reliable evidence to rate whether it works.

The evidence, ingredient by ingredient Wormwood

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Wormwood contains thujone, a neurotoxin, and safety concerns are real here. Short-term use of properly prepared products may be acceptable, but medicinal amounts and chronic use carry risk — the oil from wormwood leaves can cause muscle aches, nausea, and vomiting, and rare serious effects include kidney toxicity, muscle breakdown (rhabdomyolysis), and seizures.

Chronic heavy ingestion has been linked to addiction, hallucinations, tremors, paralysis, brain damage, and psychiatric illness. Wormwood is considered unsafe in pregnancy because it may stimulate the uterus.

There isn't enough safety information to use it while breastfeeding, so it's best avoided then too.

Side effects, ingredient by ingredient Wormwood

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Wormwood.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsants (seizure medications), stop and check with your pharmacist before using wormwood — thujone in the plant may interfere with how your drug works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Wormwood is a high-risk supplement, especially with seizure medications. If you're taking an anticonvulsant, this product isn't for you without a pharmacist or doctor's sign-off.

Even without drug interactions, the thujone content means you need to know what you're doing and why — don't use it long-term or in large amounts. Talk with your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wormwood, straight from the product label.

Brand Energique
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 318469
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wormwood by Energique, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10 Drop(s)
Maximum serving Sizes:
30 Drop(s)
Servings per container
20
IngredientAmount% DV
Proprietary Blend1.5 mL--
Wormwood0 NP--

Other ingredients: Water, Purified, Ethanol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warnings: If pregnant or breast-feeding, ask a health professional before use.

Consult a physician for use in children under 12 years of age. Keep out of reach of children.

Do not use if tamper evident seal is broken or missing.

Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Suggested use: 10 to 30 drops in water or juice 3 times daily or as otherwise directed. Shake well before use.

FDA Statement of Identity

Herbal Supplement

Formula

Artemisia absinthium (aerial parts)

Formulation

Organic and wild-crafted herbs used when possible.

Organic and wild-crafted herbs used when possible.

Brand IP Statement(s)

Energique Since 1987

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Wormwood by Energique label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Wormwood label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Wormwood by Energique

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size10 Drop(s) Dosage formLiquid Servings per container20 Amounts shown are per serving.

Proprietary Blend

1.5 mL per serving

Other (inactive) ingredients: Water, Purified, Ethanol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Wormwood by Energique Drug Interactions

Want to check YOUR meds against Wormwood?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

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50Drugs
50 Moderate

Ingredients driving the most interactions

Wormwood 50

Individual Drug Interactions

The ingredients in Wormwood interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Wormwood interact with drugs. Each result below shows which ingredient is responsible. Wormwood

Each ingredient & the kinds of drugs it affects

For each ingredient in Wormwood with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wormwood1 drug type · 50 drugs

Anticonvulsants

Theoretically, taking wormwood might interfere with the effects of anticonvulsant drugs.
Thujone, a constituent of wormwood, has convulsant effects.

Likelihood Possible Evidence D
Wormwood full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Wormwood, from the product label.

Energique

See all Energique products
Name
Energique Inc
Street Address
201 Apple Blvd
City
Woodbine
State
IA
ZipCode
51579
Phone Number
800.869.8078
Pharmacist Counseling Corner

Wormwood by Energique: Common Questions

Does Wormwood by Energique interact with any medications?
Yes. Based on its ingredients, Wormwood has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wormwood contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
No. Wormwood is considered unsafe in pregnancy because it may stimulate the uterus. There isn't enough safety data for breastfeeding, so it's best avoided then too. Talk with your doctor if you have questions about other options.
What are the side effects I should watch for?
Common effects from the wormwood oil include muscle aches, nausea, and vomiting. Rare but serious effects include kidney damage, muscle breakdown, and seizures. Chronic heavy use has been linked to hallucinations, tremors, paralysis, and brain damage. This is why short-term use of properly prepared products is safer than chronic use.
Is wormwood safe to use long-term?
No. The thujone in wormwood is toxic at higher amounts, and chronic ingestion carries real risks — including addiction, psychiatric illness, and neurological damage. Short-term use of properly prepared products is more acceptable than ongoing use.
Does this product actually work for what it claims?
The evidence isn't established for any of the conditions on the label — biliary disorders, Crohn disease, depression, dyspepsia, and osteoarthritis all have insufficient reliable evidence. That doesn't mean it won't help you, but we don't have solid proof that it does.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wormwood label
Go deeper

The Full Monographs Behind Wormwood’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Wormwood

Interacts with 50 drugs

Wormwood is a very bitter herb traditionally used to stimulate appetite and ease digestion, and it has early research interest in Crohn's disease. It contains thujone, which can be toxic in...

Read the full Wormwood monograph →
Sources

Sources & How We Checked

Wormwood's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wormwood 10 references
  1. Weisbord SD, Soule JB, Kimmel PL. Poison on line-acute renal failure caused by oil of wormwood purchased through the internet. N Engl J Med 1997;337:825-7. PubMed
  2. Gambelunghe C, Melai P. Absinthe: enjoying a new popularity among young people? Forensic Sci Int 2002;130:183-6.
  3. Hold KM, Sirisoma NS, Casida JE. Detoxification of alpha- and beta-Thujones (the active ingredients of absinthe): site specificity and species differences in cytochrome P450 oxidation in vitro and in vivo. Chem Res Toxicol 2001;14:589-95.
  4. Lachenmeier DW, Walch SG, Padosch SA, Kroner LU. Absinthe--a review. Crit Rev Food Sci Nutr 2006;46:365-77.
  5. Padosch SA, Lachenmeier DW, Kroner LU. Absinthism: a fictitious 19th century syndrome with present impact. Subst Abuse Treat Prev Policy 2006;1:14. PubMed
  6. Lachenmeier DW, Emmert J, Kuballa T, Sartor G. Thujone--cause of absinthism? Forensic Sci Int 2006;158:1-8. PubMed
  7. Dettling, A., Grass, H., Schuff, A., Skopp, G., Strohbeck-Kuehner, P., and Haffner, H. T. Absinthe: attention performance and mood under the influence of thujone. J Stud.Alcohol 2004;65(5):573-581. PubMed
  8. Benezet-Mazuecos, J. and de la Fuente, A. Electrocardiographic findings after acute absinthe intoxication. Int J Cardiol. 11-10-2006;113(2):e48-e50. PubMed
  9. El Makrini NI, Hassam B. Artemisia absinthium: burning plant! Pan Afr Med J. 2016 Jan 22;23:10. PubMed
  10. Kocaoglu C, Ozel A. Persistent metabolic acidosis and severe diarrhoea due to Artemisia absinthium poisoning. J Pak Med Assoc. 2014 Sep;64(9):1081-3.

See these in context on the Wormwood monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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