Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Yeast Beta-1,3/1,6-D-Glucan Ingredients & Drug Interactions

by Fresh Nutrition

Yeast Beta-1,3/1,6-D-Glucan label
See full label image
Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Yeast Beta-1,3/1,6-D-Glucan against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Yeast Beta-1,3/1,6-D-Glucan is a dietary supplement by Fresh Nutrition with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart health, immune support.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Yeast Beta-1,3/1,6-D-Glucan. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Yeast Beta-1,3/1,6-D-Glucan by Fresh Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Yeast Beta-1,3/1,6-D-Glucan by Fresh Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Yeast Beta-1,3/1,6-D-Glucan by Fresh Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Yeast Beta-1,3/1,6-D-Glucan, a compound derived from yeast cell walls that's been studied for its effects on cholesterol and heart health. The capsule itself is vegetarian.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Beta-glucans's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: strengthen immune function.
  • We looked for evidence on: Allergic rhinitis (hay fever), Chronic fatigue syndrome (CFS), Critical illness (trauma), Exercise-induced respiratory infections, Lower respiratory tract infections, Lyme disease — and 4 related terms.
  • The closest evidence on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS), Upper respiratory tract infection (URTI), Exercise-induced respiratory infections, Lower respiratory tract infections, and more.

The evidence supports beta-glucans for two main uses: raising cholesterol (dyslipidemia) and supporting coronary heart disease — both rated Likely Effective. This means clinical research shows real benefit for these conditions, though individual results vary.

The evidence, ingredient by ingredient Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from everyday food sources are generally well tolerated. However, concentrated supplements like this one lack robust safety data, so use caution.

Topically applied beta-glucan creams have caused mild skin reactions in some people, though these resolved on their own. There's little research on supplement doses during breastfeeding, so talk with your pharmacist or doctor before using it if you're nursing.

Side effects, ingredient by ingredient Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this product if you take blood pressure medications or immunosuppressants (drugs that weaken your immune system). Beta-glucans may lower blood pressure and boost immune activity, both of which could affect how these drugs work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you're looking to support cholesterol and heart health and don't take blood pressure or immune-suppressing medications, this supplement is worth discussing with your pharmacist. If you're on either of those drug classes, check your specific medications first — the interaction risk is real.

And if you're pregnant or breastfeeding, get personalized advice before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Yeast Beta-1,3/1,6-D-Glucan, straight from the product label.

Brand Fresh Nutrition
Barcode (UPC) 850012956631
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 241906
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Yeast Beta-1,3/1,6-D-Glucan by Fresh Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
20
UPC/BARCODE
850012956631
IngredientAmount% DV
Yeast Beta-1,3/1,6-D-Glucan200 mg--

Other ingredients: Vegetarian Capsules

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Vegan

Non GMO Gluten free Soy free

No artificial colors. No artificial flavors. No preservatives. Made with Non-GMO, all natural ingredients!

Made with Non-GMO, all natural ingredients!

All natural

Promotes gut health Maximum bioavailability May support immune function May assist digestion

Fresh Nutrition produces the most potent and highest quality Yeast Beta-1,3/1,6-D-Glucan. Our raw materials are carefully sourced and cultivated; contain no fillers, additives, and are manufactured domestically in a cGMP facility. Thank you for choosing Fresh!

Formula

Yeast Beta-1,3/1,6-D-Glucan Yeast Beta-1,3/1,6-D-Glucan is a scientifically proven way to strengthen immune function. Naturally occurring in cereals and fungi, beta glucans commonly include a 1,3 glycosidic and 1,6-glucan yeast-cell-wall-derived linkage. A well-functioning immune system is key to staying healthy and Beta 1,3/1,6-D-Glucan is a certified generally recognized as safe (GRAS) way to stimulate immunity.

General Statements

Fresh Nutrition Our goal is to create high-quality natural products using both organic and responsibly sourced ingredients to optimize health and well-being.

Suggested/Recommended/Usage/Directions

Recommended Dosage Take three (3) capsules daily with sufficient water before a meal.

Seals/Symbols

Quality Verified Third Party Tested For Quality And Purity To provide our consumers with complete confidence in our product quality, every batch is 3rd party tested for quality & purity.

Made in USA

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Yeast Beta-1,3/1,6-D-Glucan by Fresh Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Yeast Beta-1,3/1,6-D-Glucan label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Yeast Beta-1,3/1,6-D-Glucan by Fresh Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container20 Amounts shown are per serving.

Yeast Beta-1,3/1,6-D-Glucan

Interacts with
293 drugs
200 mg per serving

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly low...

Yeast Beta-1,3/1,6-D-Glucan monograph & interactions

Other (inactive) ingredients: Vegetarian Capsules. These complete the product’s ingredient list but are not active constituents.

Interaction report

Yeast Beta-1,3/1,6-D-Glucan by Fresh Nutrition Drug Interactions

Want to check YOUR meds against Yeast Beta-1,3/1,6-D-Glucan?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Yeast Beta-1,3/1,6-D-Glucan 293

Individual Drug Interactions

The ingredients in Yeast Beta-1,3/1,6-D-Glucan interact with 293 drugs. Click any drug to see the details.

1 of the 1 ingredient in Yeast Beta-1,3/1,6-D-Glucan interact with drugs. Each result below shows which ingredient is responsible. Yeast Beta-1,3/1,6-D-Glucan

Each ingredient & the kinds of drugs it affects

For each ingredient in Yeast Beta-1,3/1,6-D-Glucan with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Yeast Beta-1,3/1,6-D-Glucan2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
Yeast Beta-1,3/1,6-D-Glucan full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Yeast Beta-1,3/1,6-D-Glucan, from the product label.

Fresh Nutrition

See all Fresh Nutrition products
Name
Fresh Nutrition by Excelsior Nutrition Inc.
Street Address
1601 Dove St
City
Newport Beach
State
California
ZipCode
92660
Web Address
www.fresh-nutrition.com
Pharmacist Counseling Corner

Yeast Beta-1,3/1,6-D-Glucan by Fresh Nutrition: Common Questions

Does Yeast Beta-1,3/1,6-D-Glucan by Fresh Nutrition interact with any medications?
Yes. Based on its ingredients, Yeast Beta-1,3/1,6-D-Glucan has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Yeast Beta-1,3/1,6-D-Glucan contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this actually work for cholesterol and heart health?
Yes — the evidence rates beta-glucans as Likely Effective for both high cholesterol and supporting coronary heart disease. That means clinical research backs real benefit, though it won't work the same for everyone.
What are the side effects?
Oral beta-glucans are generally well tolerated. In one clinical trial of children with a serious condition taking a very high dose, one patient showed temporary liver enzyme elevation, but this is rare. Topical creams have occasionally caused mild skin reactions that went away on their own.
Can I take this if I'm pregnant?
The data doesn't tell us one way or the other, so there isn't enough information to know if it's safe. Talk with your doctor or pharmacist for advice tailored to your pregnancy.
Is it safe to take while breastfeeding?
There's very little research on supplement doses during breastfeeding. Because of that gap, caution is advised — speak with your pharmacist or doctor before using it.
Are there any fillers or other junk in here?
The capsule is made from vegetarian material. Otherwise, it's just the active ingredient — no other fillers listed.
Why does this interact with so many medications?
It doesn't interact with 287 different drugs directly. That number reflects the total count of individual medications across the drug types that beta-glucans *do* interact with — mainly blood pressure drugs and immunosuppressants. Most people won't take any of them.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Yeast Beta-1,3/1,6-D-Glucan is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Yeast Beta-1,3/1,6-D-Glucan label
Go deeper

The Full Monographs Behind Yeast Beta-1,3/1,6-D-Glucan’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beta-glucans

Interacts with 293 drugs

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...

Read the full Beta-glucans monograph →
Sources

Sources & How We Checked

Yeast Beta-1,3/1,6-D-Glucan's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team