Acetazolamide
46 interactions 434 cited referencesAcetazolamide is a diuretic medication used to treat glaucoma, altitude sickness, fluid retention, and certain types of epilepsy. Read the full Acetazolamide drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Acetazolamide Amphetamine Dexedrine Increased exposure to amphetamine Details Acetazolamide Arsenic Trioxide Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Acetazolamide Articaine An increased risk of methemoglobinemia Details Acetazolamide Aspirin Acuprin® Salicylate toxicity (vomiting, tachycardia, hyperpnea, mental confusion) or acetaZOLAMIDE toxicity (fatigue, lethargy, somnolence,... Details Acetazolamide Azathioprine Azasan An increased risk of hepatotoxicity Details Acetazolamide Benzphetamine Increased exposure to amphetamine Details Acetazolamide Carbamazepine Carbatrol Increased carBAMazepine exposure Details Acetazolamide Dextroamphetamine Dexedrine Increased exposure to amphetamine Details Acetazolamide Digitalis Digitalis toxicity (nausea, vomiting, arrhythmias) Details Acetazolamide Digoxin Cardoxin® Digitalis toxicity (nausea, vomiting, arrhythmias) Details Acetazolamide Hydroxychloroquine Plaquenil Impaired antiepileptic activity Details Acetazolamide Insulin Aspart, Recombinant Fiasp An increased risk of hypoglycemia Details Acetazolamide Insulin Glargine, Recombinant Basaglar An increased risk of hypoglycemia Details Acetazolamide Insulin Icodec-Abae Awiqli An increased risk of hypoglycemia Details Acetazolamide Levoketoconazole Recorlev Increased risk of serious hepatotoxicity and drug-induced liver injury Details Acetazolamide Levomethadyl Increased risk of QT prolongation Details Acetazolamide Lidocaine Akten An increased risk of methemoglobinemia Details Acetazolamide Lisdexamfetamine Arynta Increased exposure to amphetamine Details Acetazolamide Lithium Decreased lithium effectiveness or increased lithium concentrations Details Acetazolamide Memantine Namenda Reduced clearance of memantine Details Acetazolamide Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Acetazolamide Metformin Fortamet® An increased risk of lactic acidosis and reduced serum bicarbonate Details Acetazolamide Methamphetamine Desoxyn Increased exposure to amphetamine Details Acetazolamide Methotrexate Jylamvo Increased methotrexate exposure, an increased the risk of methotrexate-related severe AR, may also subsequently reduce active meta... Details Acetazolamide Orlistat Alli Reduced efficacy of anticonvulsant Details Acetazolamide Pimozide An increased risk of seizure Details Acetazolamide Porfimer Excessive intracellular damage in photosensitized tissues Details Acetazolamide Primidone Mysoline Reduced serum concentrations of primidone and its metabolites and decreased anticonvulsant effect Details Acetazolamide Proscillaridin Digitalis toxicity (nausea, vomiting, arrhythmias) Details Acetazolamide Quinidine Cardioquin® Enhanced quinidine effects and quinidine toxicity Details Acetazolamide Sotalol Betapace An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Acetazolamide Topiramate Eprontia An increased risk of nephrolithiasis and severity of metabolic acidosis Details Acetazolamide Arsenic Trioxide Injection Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Acetazolamide Aspirin Rectal Aspirin Salicylate toxicity (vomiting, tachycardia, hyperpnea, mental confusion) or acetaZOLAMIDE toxicity (fatigue, lethargy, somnolence,... Details Acetazolamide Lithium Carbonate Lithobid Decreased lithium effectiveness or increased lithium concentrations Details Acetazolamide Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased the risk of methotrexate-related severe AR, may also subsequently reduce active meta... DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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