Dolasetron

332 interactions 1 explained in plain English 421 cited references

Also sold as: Anzemet Anzemet®

About Dolasetron

Dolasetron is used to prevent nausea and vomiting caused by cancer chemotherapy. Dolasetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. Read the full Dolasetron drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

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16 Contraindicated 314 Major 1 Moderate 1 Minor

All (332) Contraindicated (16) Major (314) Moderate (1) Minor (1)

Major

Dolasetron Degarelix Firmagon Increased risk of QT interval prolongation Details Dolasetron Delamanid Increased risk of QT interval prolongation Details Dolasetron Desflurane Suprane An increased risk of QT interval prolongation Details Dolasetron Desipramine Norpramin Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Desvenlafaxine Pristiq Increased risk of serotonin syndrome Details Dolasetron Dexmedetomidine Dexased Increased risk of cardiac arrhythmias Details Dolasetron Dextroamphetamine Dexedrine An increased risk of serotonin syndrome Details Dolasetron Dextromethorphan Delsym Increased risk of serotonin syndrome Details Dolasetron Dibenzepin Increased risk of serotonin syndrome Details Dolasetron Dihydrocodeine Increased risk of serotonin syndrome Details Dolasetron Domperidone Increased risk of QT interval prolongation Details Dolasetron Donepezil Adlarity Increased risk of QT-interval prolongation and torsade de pointes Details Dolasetron Dordaviprone An increased risk of QT interval prolongation Details Dolasetron Doxepin Prudoxin Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Droperidol An increased risk of QT interval prolongation Details Dolasetron Duloxetine Increased risk of serotonin syndrome Details Dolasetron Efavirenz An increased risk of QT interval prolongation Details Dolasetron Eletriptan Relpax Increased risk of serotonin syndrome Details Dolasetron Encorafenib Braftovi Increased risk of QT interval prolongation Details Dolasetron Enflurane An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Dolasetron Erythromycin Erythrocin Stearate Increased risk of QT interval prolongation Details Dolasetron Escitalopram Lexapro Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Etrasimod Velsipity Increased risk of transient reduction in heart rate, AV conduction, QT interval prolongation and an increased risk of torsade de p... Details Dolasetron Fenfluramine An increased risk of serotonin syndrome (hypertension, tachycardia, hyperthermia, myoclonus, mental status changes) Details Dolasetron Fentanyl Increased risk of serotonin syndrome Details Dolasetron Fexinidazole An increased risk of QT interval prolongation Details Dolasetron Fingolimod Gilenya Increased risk of QT interval prolongation Details Dolasetron Flecainide Tambocor® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Fluconazole Diflucan An increased risk of QT interval prolongation Details Dolasetron Fluoxetine RECONCILE Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Fluvoxamine Increased risk of serotonin syndrome Details Dolasetron Formoterol Perforomist Increased risk of QT interval prolongation and an increased risk of cardiovascular adverse effects Details Dolasetron Foscarnet Foscavir An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Fosfomycin Contepo An increased risk of QT interval prolongation Details Dolasetron Fosphenytoin Cerebyx An increased risk of QT interval prolongation Details Dolasetron Fostemsavir Rukobia Increased risk of torsade de pointes Details Dolasetron Frovatriptan Frova Increased risk of serotonin syndrome Details Dolasetron Furazolidone Increased risk of serotonin syndrome Details Dolasetron Gatifloxacin Zymaxid An increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.