Imatinib

Major

Imatinib Edoxaban Savaysa Increased edoxaban exposure Details Imatinib Elacestrant Orserdu Increased elacestrant exposure and an increased risk of elacestrant-related adverse effects Details Imatinib Encorafenib Braftovi Increased encorafenib exposure and an increased risk of encorafenib-related adverse events Details Imatinib Entrectinib Rozlytrek Increased entrectinib exposure and an increased frequency or severity of adverse reactions Details Imatinib Everolimus Afinitor Increased CYP3A4 substrate with NTI exposure and an increased risk of CYP3A4 substrates with NTI-related adverse reactions Details Imatinib Fentanyl Transdermal Patch Duragesic® Increased fentaNYL exposure and an increased risk of prolonged opioid effects Details Imatinib Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Imatinib Flecainide Tambocor® Increased CYP2D6 substrate exposure with NTI exposure and an increased risk of CYP2D6 substrates with NTI-related adverse reaction... Details Imatinib Gemfibrozil Lopid Increased imatinib trough level or reduced imatinib exposure Details Imatinib Ibrutinib Imbruvica Increased ibrutinib exposure Details Imatinib Ifosfamide Injection Ifex Decreased ifosfamide effectiveness Details Imatinib Infigratinib Truseltiq Increased infigratinib plasma concentrations Details Imatinib Ivabradine Corlanor Increased exposure of ivabradine Details Imatinib Ketoconazole Topical Extina® Foam Increased imatinib exposure and an increased ketoconazole exposure Details Imatinib Lefamulin Xenleta Increased lefamulin exposure and an increased risk of lefamulin-related adverse reactions Details Imatinib Letermovir Injection Prevymis Increased CYP3A substrate exposure Details Imatinib Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse reactions Details Imatinib Lumateperone Caplyta Increased lumateperone exposure and increased risk of lumateperone-related adverse reactions Details Imatinib Lurasidone Latuda Increased lurasidone exposure Details Imatinib Lurbinectedin Injection Zepzelca Increased lurbinectedin exposure and an increased risk of lurbinectedin-related adverse reactions Details Imatinib Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Imatinib Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Imatinib Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Imatinib Methylergonovine Methergine Increased methylergonovine exposure and an increased risk of vasospasm, cerebral ischemia and/or ischemia of extremities Details Imatinib Mexiletine Mexitil® Increased CYP2D6 substrate exposure with NTI exposure and an increased risk of CYP2D6 substrates with NTI-related adverse reaction... Details Imatinib Midazolam Nasal Spray Nayzilam Increased midazolam exposure and increased risk for prolonged sedation Details Imatinib Midazolam Injection Nayzilam Increased midazolam exposure and increased risk for prolonged sedation Details Imatinib Midostaurin Rydapt Increased CYP3A4 substrate with NTI exposure and an increased risk of CYP3A4 substrates with NTI-related adverse reactions Details Imatinib Mitapivat Aqvesme Increased mitapivat exposure Details Imatinib Naloxegol Movantik Increased naloxegol exposure Details Imatinib Neratinib Nerlynx Increased CYP3A4 substrate with NTI exposure and an increased risk of CYP3A4 substrates with NTI-related adverse reactions Details Imatinib Nifedipine Adalat® Increased NIFEdipine exposure Details Imatinib Olaparib Lynparza Increased olaparib exposure Details

Moderate

Imatinib Abemaciclib Verzenio Explained Increased abemaciclib plasma concentration Details Imatinib Avanafil Stendra Increased avanafil exposure Details Imatinib Guanfacine Intuniv Increased guanfacine exposure Details Imatinib Hydrocortisone Ala-Cort Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Imatinib Hydrocortisone Injection A-Hydrocort® Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Imatinib Levothyroxine Ermeza Increased risk of hypothyroidism Details