Drug & supplement interaction

7-alpha-hydroxy-dhea + Levorphanol

Levorphanol brand name: Levo-Dromoran.

No Known Interaction
The bottom line No known interaction

We found no known interaction between 7-alpha-hydroxy-dhea and Levorphanol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

7-alpha-hydroxy-dhea and Levorphanol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Levorphanol and 7-alpha-hydroxy-dhea in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for 7-alpha-hydroxy-dhea at all — not against Levorphanol, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

7-alpha-hydroxy-dhea safety at a glance

7-alpha-hydroxy-dh... overall Not established Human safety data for 7-alpha-hydroxy-DHEA as a supplement is very limited.
Pregnancy Avoid Hormone-related products should be avoided during pregnancy due to unknown risks.
Breastfeeding Avoid Not enough safety information; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Levorphanol and 7-alpha-hydroxy-dhea? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Levorphanol’s Own FDA Label Lists

This is not an interaction — none of it involves 7-alpha-hydroxy-dhea. These are the most notable effects listed in the ADVERSE REACTIONS section of Levorphanol’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Dependence or withdrawal symptoms Worth acting on
  • Serotonin syndrome Worth acting on
  • Thoughts of self-harm Worth acting on
  • Memory problems Worth acting on
  • Trouble passing urine Worth acting on
  • Low blood sugar Worth acting on
  • A slow heartbeat Worth acting on
  • Confusion Worth acting on
  • Seizures Worth acting on
  • Low mood Worth acting on

Showing the 10 most notable of 30 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Levorphanol. Read the label on DailyMed › 7-alpha-hydroxy-dhea’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no 7-alpha-hydroxy-dhea side to compare — that is a limit of the record, not a statement that 7-alpha-hydroxy-dhea has no side effects.

Everything else you take

See Every Supplement That Interacts With Levorphanol

This page covers 7-alpha-hydroxy-dhea only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Levorphanol page lists 100 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).

By severity: 7 major · 78 moderate · 15 minor.

From our pharmacist’s overview on the Levorphanol page

“Most of the ingredients that interact with levorphanol (Levo-Dromoran) pile onto the same hazard, deeper sedation. Because levorphanol is a potent opioid painkiller, that stacking can slow breathing rather than just cause drowsiness, so this page deserves real vigilance before you add a supplement to it.”

Reviewed by 2 · Jul 18, 2026

Open the Levorphanol interaction page

One more smart check

Taking 7-alpha-hydroxy-dhea as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing 7-alpha-hydroxy-dhea, each one broken down to its full ingredient list — and combination products often carry several ingredients besides 7-alpha-hydroxy-dhea. Even though 7-alpha-hydroxy-dhea itself has no known interaction with Levorphanol, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where 7-alpha-hydroxy-dhea and Levorphanol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement 7-alpha-hydroxy-dhea
Steady interest

#1,282 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Levorphanol
Top 25%

#339 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. 7-alpha-hydroxy-dhea is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every 7-alpha-hydroxy-dhea reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The 7-alpha-hydroxy-dhea and Levorphanol records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About 7-alpha-hydroxy-dhea

What is 7-alpha-hydroxy-dhea?

  • Anti-aging support
  • Immune support
  • Weight management
  • Energy and vitality
  • Hormone metabolism support

7-alpha-hydroxy-DHEA is a natural breakdown product (metabolite) of the adrenal hormone DHEA, and very little reliable human research exists on taking it as a supplement. Because it is hormone-related and poorly studied, the safest approach is to avoid it unless a knowledgeable doctor or pharmacist advises otherwise.

Not a plant; this is a hormone metabolite (made in the body or made synthetically for supplements) · Capsules, tablets, sublingual products (often marketed as part of DHEA-related supplements)

An interaction check asks whether these two react with each other — it does not ask whether 7-alpha-hydroxy-dhea is a good idea for someone in your situation. Here is what our 7-alpha-hydroxy-dhea record says about it on its own.

7-alpha-hydroxy-dhea: dosing

There is no established or standardized dose for 7-alpha-hydroxy-DHEA. Reliable studies that would tell us a safe and effective amount are lacking.If a product is used, follow the directions on the label and do not exceed them.

From our 7-alpha-hydroxy-dhea monograph — the full record covers uses, side effects and every documented interaction.

Read the full 7-alpha-hydroxy-dhea monograph & all interactions
Medication

About Levorphanol

What Is Levorphanol Used For?

Brand name: Levo-Dromoran

Levorphanol Tartrate Tablets are used to manage pain severe enough to require an opioid — specifically when non-opioid or other pain treatments haven't provided enough relief or aren't a good fit for the patient.

It is not meant for everyday or mild pain. Prescribers weigh the serious risks of opioid therapy carefully before choosing this medication, and it should be used for only as long as the pain requires it.

See full Levorphanol drug information
Keep checking

Other Drugs & 7-alpha-hydroxy-dhea

Browse every other medication we’ve checked against 7-alpha-hydroxy-dhea — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

7-alpha-hydroxy-dhea References

The 2 sources that drive our 7-alpha-hydroxy-dhea monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. 7-alpha-hydroxy-dhea is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. DHEA — MedlinePlus Source
  2. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking 7-alpha-hydroxy-dhea and Levorphanol Together: Common Questions

Is it safe to take 7-alpha-hydroxy-dhea with Levorphanol?
We do not list a known interaction between 7-alpha-hydroxy-dhea and Levorphanol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Levorphanol interact with any supplements?
Yes. Levorphanol has documented interactions with 100 supplements in our database — 7-alpha-hydroxy-dhea is not one of them. The Levorphanol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Levorphanol and 7-alpha-hydroxy-dhea?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.