Drug & supplement interaction

Arabinoxylan + Tolnaftate

Tolnaftate brand name: Tinactin.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Arabinoxylan and Tolnaftate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Arabinoxylan and Tolnaftate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tolnaftate and Arabinoxylan in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Arabinoxylan safety at a glance

Arabinoxylan overall Use caution Generally considered well tolerated as a food-derived fiber, but high-quality long-term safety data are limited.
Pregnancy Use caution Not enough reliable data on supplement use; stick to fiber from normal foods unless your provider advises otherwise.
Breastfeeding Use caution There is little safety information for supplements while breastfeeding, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tolnaftate and Arabinoxylan? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Tolnaftate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Tolnaftate is filed under 2 classifications — antifungals, oral drugs. Arabinoxylan has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Tolnaftate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Arabinoxylan Does Interact With Other Medications

Arabinoxylan has 86 moderate known drug interactions in our database — Tolnaftate isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Tolnaftate)
Taking anything else?

Check Another of Your Medications Against Arabinoxylan

Covers the 2,830 medications we’ve checked against Arabinoxylan. Pick one to open its full report.

What to actually watch for

What Arabinoxylan Itself Has Been Linked To

This is not an interaction — nothing below involves Tolnaftate. It is the side-effect record for Arabinoxylan on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Arabinoxylan, this list is the first place to look.

  • Bloating or gas / Stomach pain / Diarrhea Additional detail

    “Orally, arabinoxylan seems to be well tolerated. Some adverse effects reported in clinical trials include diarrhea, gas, bloating, and abdominal pain.”

    Arabinoxylan · Natural Medicines adverse-effect record, reported in diarrhea.

    3 sources cited
    1. 25664. Grasten S, Liukkonen K-H, Chrevatidis A, et al. Effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function in healthy humans. Nutrition Res 2003;23:1503-14. DOI
    2. 99677. François IE, Lescroart O, Veraverbeke WS, et al. Effects of a wheat bran extract containing arabinoxylan oligosaccharides on gastrointestinal health parameters in healthy adult human volunteers: a double-blind, randomised, placebo-controlled, cross-over t
    3. 99680. Scarpellini E, Deloose E, Vos R, et al, The effect of arabinoxylooligosaccharides on gastric sensory-motor function and nutrient tolerance in man. Neurogastroenterol Motil. 2016 Aug;28(8):1194-203. PubMed

    “Orally, arabinoxylan can cause gastrointestinal adverse effects such as diarrhea, gas, bloating, and abdominal pain.”

    Arabinoxylan · Natural Medicines adverse-effect record, reported in diarrhea.

    3 sources cited
    1. 25664. Grasten S, Liukkonen K-H, Chrevatidis A, et al. Effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function in healthy humans. Nutrition Res 2003;23:1503-14. DOI
    2. 99677. François IE, Lescroart O, Veraverbeke WS, et al. Effects of a wheat bran extract containing arabinoxylan oligosaccharides on gastrointestinal health parameters in healthy adult human volunteers: a double-blind, randomised, placebo-controlled, cross-over t
    3. 99680. Scarpellini E, Deloose E, Vos R, et al, The effect of arabinoxylooligosaccharides on gastric sensory-motor function and nutrient tolerance in man. Neurogastroenterol Motil. 2016 Aug;28(8):1194-203. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Arabinoxylan — expand a row for the licensed statement it rests on. We haven’t matched Tolnaftate to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Tolnaftate.

From our Q&A

Questions About Arabinoxylan or Tolnaftate

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Arabinoxylan or Tolnaftate, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Tolnaftate

This page covers Arabinoxylan only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tolnaftate page lists 20 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 12 minor.

From our pharmacist’s overview on the Tolnaftate page

“For anyone using tolnaftate (Tinactin), the antifungal in athlete's foot creams and sprays, activated charcoal is the interaction to understand before all others. It holds the only major rating among the 20 ingredients on file, since charcoal binds many medicines and can lower how much reaches the body, even drugs not given by mouth.”

Reviewed by 2 · Jul 18, 2026

Open the Tolnaftate interaction page

One more smart check

Taking Arabinoxylan as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Arabinoxylan, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Arabinoxylan. Even though Arabinoxylan itself has no known interaction with Tolnaftate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Arabinoxylan and Tolnaftate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Arabinoxylan
Steady interest

#961 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tolnaftate
Steady interest

#2,322 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Arabinoxylan reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Arabinoxylan and Tolnaftate records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Arabinoxylan

What is Arabinoxylan?

Arabinoxylan
  • Blood sugar support
  • Digestive and gut health (prebiotic)
  • Cholesterol and triglyceride support
  • Immune support
  • Metabolic syndrome

Arabinoxylan is a type of dietary fiber found in cereal grains that acts as a prebiotic and may modestly affect blood sugar and blood fats. The evidence for most uses is early and limited, so it should not replace proven treatments. If you are considering it, talk with your pharmacist or doctor first.

Fiber extracted from the cell walls of cereal grains (such as wheat bran, rice bran, corn, rye, oat, and barley) · Powder, capsules, and a modified rice-bran product known as MGN-3 (Biobran)

An interaction check asks whether these two react with each other — it does not ask whether Arabinoxylan is a good idea for someone in your situation. Here is what our Arabinoxylan record says about it on its own.

Arabinoxylan: dosing

There is no official or standardized dose of arabinoxylan, and amounts used in studies have varied widely depending on the product and the goal.The best approach is to follow the directions on the specific product label and to start low and increase slowly to limit gas and bloating.

From our Arabinoxylan monograph — the full record covers uses, side effects and every documented interaction.

Read the full Arabinoxylan monograph & all interactions
Medication

About Tolnaftate

What Is Tolnaftate Used For?

Brand name: Tinactin

Tolnaftate treats common fungal skin infections — specifically athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis). It also helps relieve the itching, cracking, burning, scaling, redness, and soreness that come with these infections.

Several products also help prevent athlete's foot from coming back with regular daily use. Note that tolnaftate is not effective on the scalp or nails — though some patch products are applied around the nail and cuticle area to address skin surrounding the nail.

Most-Reported Side Effects for Tolnaftate

From FAERS, the FDA’s public side-effect reporting system (1,403 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 88 reports
Nausea 86 reports
Dyspnea 80 reports
Diarrhea 73 reports
Anxiety 69 reports
See full Tolnaftate drug information
Keep checking

Other Drugs & Arabinoxylan

Browse every other medication we’ve checked against Arabinoxylan — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Arabinoxylan page.

No interaction 2,743 drugs checked — show the list

We also checked Arabinoxylan against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Arabinoxylan list.

See the full Arabinoxylan interactions page
See every supplement checked against Tolnaftate, ranked by severity
Evidence & sources

Arabinoxylan References

The 8 references that drive our Arabinoxylan monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Grasten S, Liukkonen K-H, Chrevatidis A, et al. Effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function in healthy humans. Nutrition Res 2003;23:1503-14. DOI
  2. Lu ZX, Walker KZ, Muir JG, Mascara T, O'Dea K. Arabinoxylan fiber, a byproduct of wheat flour processing, reduces the postprandial glucose response in normoglycemic subjects. Am J Clin Nutr 2000;71(5):1123-1128.
  3. Lu ZX, Walker KZ, Muir JG, O'Dea K. Arabinoxylan fibre improves metabolic control in people with Type II diabetes. Eur J Clin Nutr 2004;58(4):621-8. PubMed
  4. Garcia AL, Otto B, Reich SC, et al. Arabinoxylan consumption decreases postprandial serum glucose, serum insulin and plasma total ghrelin response in subjects with impaired glucose tolerance. Eur J Clin Nutr 2007;61(3):334-41. PubMed
  5. Garcia AL, Steiniger J, Reich SC, et al. Arabinoxylan fibre consumption improved glucose metabolism, but did not affect serum adipokines in subjects with impaired glucose tolerance. Horm Metab Res 2006;38(11):761-766. PubMed
  6. François IE, Lescroart O, Veraverbeke WS, et al. Effects of a wheat bran extract containing arabinoxylan oligosaccharides on gastrointestinal health parameters in healthy adult human volunteers: a double-blind, randomised, placebo-controlled, cross-over t
  7. Schioldan AG, Gregersen S, Hald S, et al. Effects of a diet rich in arabinoxylan and resistant starch compared with a diet rich in refined carbohydrates on postprandial metabolism and features of the metabolic syndrome. Eur J Nutr. 2018 Mar;57(2):795-807. PubMed
  8. Scarpellini E, Deloose E, Vos R, et al, The effect of arabinoxylooligosaccharides on gastric sensory-motor function and nutrient tolerance in man. Neurogastroenterol Motil. 2016 Aug;28(8):1194-203. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Arabinoxylan and Tolnaftate Together: Common Questions

Is it safe to take Arabinoxylan with Tolnaftate?
We do not list a known interaction between Arabinoxylan and Tolnaftate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Arabinoxylan and Tolnaftate combination checked?
Interactions in our licensed database are recorded against drug classes. Tolnaftate is filed under 2 classifications, and Arabinoxylan has documented interactions with 1 drug class — none of Tolnaftate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Arabinoxylan interact with any other medications?
Yes. Arabinoxylan has 86 documented drug interactions in our database — Tolnaftate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Tolnaftate interact with any supplements?
Yes. Tolnaftate has documented interactions with 20 supplements in our database — Arabinoxylan is not one of them. The Tolnaftate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Arabinoxylan monograph Uses, safety profile, and every drug interaction in one place Tolnaftate drug information The full plain-English guide to this medication Tolnaftate supplement interactions Every supplement checked against Tolnaftate, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 8 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Tolnaftate and Arabinoxylan?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.