Drug & supplement interaction

Babassu + Phenprocoumon

Phenprocoumon brand name: Liquamar.

Moderate Interaction
The bottom line Moderate

Babassu has a moderate interaction with Phenprocoumon. Evidence from animal research suggests that babassu has antithrombotic effects.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Babassu and Phenprocoumon

Here is the interaction we found between these two, with the evidence behind it.

Moderate

ANTICOAGULANT/ANTIPLATELET DRUGS

Why this applies to Phenprocoumon

Phenprocoumon falls under ANTICOAGULANT/ANTIPLATELET DRUGS — the group Babassu interacts with.

Evidence from animal research suggests that babassu has antithrombotic effects. Theoretically, babassu might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs. Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Phenprocoumon (Liquamar) is a strong blood thinner, similar to warfarin, and it has a narrow safety window where small changes can tip you toward bleeding. The concern here is that babassu may have its own mild blood-thinning, clot-fighting activity. If that effect is real in people, layering it on top of phenprocoumon could add up and raise your bleeding risk.

I want to be honest about how soft this evidence is: it comes only from lab and animal studies, not human trials, so it's theoretical at this point. Still, with a drug like this, I'd play it safe. Watch for warning signs like easy bruising, nosebleeds, bleeding gums, or dark stools, and please check with your pharmacist or doctor before adding babassu.

References
  1. Azevedo, A. P., Farias, J. C., Costa, G. C., Ferreira, S. C., Aragao-Filho, W. C., Sousa, P. R., Pinheiro, M. T., Maciel, M. C., Silva, L. A., Lopes, A. S., Barroqueiro, E. S., Borges, M. O., Guerra, R. N., and Nascimento, F. R. Anti-thrombotic effect of

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Babassu Also Interacts With Other Medications

Babassu has 126 moderate known drug interactions in our database — the Phenprocoumon one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Babassu

Covers the 2,830 medications we’ve checked against Babassu. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Phenprocoumon

This page covers Babassu only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Phenprocoumon page lists 219 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Danshen (major), Piracetam (major), St. John's Wort (major) and Aconite (moderate).

By severity: 4 major · 190 moderate · 25 minor.

From our pharmacist’s overview on the Phenprocoumon page

“Phenprocoumon (Liquamar) is a blood thinner in the coumarin family, a close cousin of warfarin, and small shifts in its blood level can tip you toward a clot or a bleed, so I treat this list with genuine care. Almost everything on it pushes the drug's effect further, layering extra bleeding risk on blood that is already thinned.”

Reviewed by 2 · Jul 18, 2026

Open the Phenprocoumon interaction page

How much people look this up

Where Babassu and Phenprocoumon Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Babassu
Steady interest

#812 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Phenprocoumon
Top half

#781 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Babassu

What is Babassu?

Babassu
  • Skin and hair care
  • Inflammation
  • Wound healing
  • Digestive complaints
  • General wellness

Babassu comes from a Brazilian palm tree, and its oil and mesocarp flour are used in foods, cosmetics, and traditional remedies. Early lab and animal studies suggest possible anti-inflammatory and wound-healing effects, but there is very little human research to confirm any health benefit. If you want to try it, talk with your pharmacist or doctor first.

Read the full Babassu monograph & all interactions
Keep checking

Other Drugs & Babassu

Browse every other medication we’ve checked against Babassu — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
126Moderate
0Minor
2,703No known interaction
Moderate

126 interactions

Showing 60 of 126 moderate interactions — see all 126 on the Babassu page.

No interaction 2,703 drugs checked — show the list
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Babassu and Phenprocoumon Together: Common Questions

Can you take Babassu with Phenprocoumon?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Babassu and Phenprocoumon interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.