Medication interaction hub

What Supplements Interact with Phenprocoumon?

Phenprocoumon brand name: Liquamar. Every interaction below applies to the brands too.

219 Interactions 4 Major 190 Moderate 25 Minor
Curated & coded by · Clinical Pharmacist · Updated September 23, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Phenprocoumon? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Phenprocoumon against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Phenprocoumon (Liquamar) is a blood thinner in the coumarin family, a close cousin of warfarin, and small shifts in its blood level can tip you toward a clot or a bleed, so I treat this list with genuine care. Almost everything on it pushes the drug's effect further, layering extra bleeding risk on blood that is already thinned. The entry that concerns me most works in reverse: St. John's wort speeds phenprocoumon's breakdown and can quietly leave you underprotected against clots, and that finding comes from solid human evidence.

A smaller group interferes with absorption instead, activated charcoal chief among them; it binds phenprocoumon in the gut, so the two need spacing far apart. The other two major-rated entries push bleeding risk. Most of the 190 moderate entries are theoretical additive bleeding effects, with 25 minor besides, but the four rated major are where I would start reading.

— , Clinical Pharmacist · July 18, 2026

Major 4 Moderate 190 Minor 25 No known interaction 1,233

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Phenprocoumon: Top Interactions at a Glance

The Phenprocoumon supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 219 interacting ingredients — plus 1,233 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Phenprocoumon Combinations Today

The Phenprocoumon + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Baikal Skullcap + Phenprocoumoni

Theoretically, Baikal skullcap might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.

Read the full interaction Moderate Likelihood Possible Lycopene + Phenprocoumoni

Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Read the full interaction Minor Likelihood Unlikely Magnesium + Phenprocoumoni

Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.

Read the full interaction Moderate Likelihood Possible Gamma-linolenic Acid (gla) + Phenprocoumoni

Theoretically, GLA might increase the risk of bleeding when taken with anticoagulant or antiplatelet rugs.

Read the full interaction Moderate Likelihood Possible Kinetin + Phenprocoumoni

In vitro research suggests that kinetin inhibits human platelet aggregation and activation.

Read the full interaction Moderate Likelihood Possible Pau D'arco + Phenprocoumoni

Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Read the full interaction
The complete list

Every Supplement Checked Against Phenprocoumon

All 1,452 ingredients in our database, ranked by severity — 219 with a Phenprocoumon interaction on file and 1,233 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Phenprocoumon?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Baikal Skullcap with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Baikal skullcap might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.

Full Baikal Skullcap + Phenprocoumon answer

Can you take Lycopene with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Full Lycopene + Phenprocoumon answer

Can you take Magnesium with Phenprocoumon?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.

Full Magnesium + Phenprocoumon answer

Can you take Gamma-linolenic Acid (gla) with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, GLA might increase the risk of bleeding when taken with anticoagulant or antiplatelet rugs.

Full Gamma-linolenic Acid (gla) + Phenprocoumon answer

Can you take Kinetin with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that kinetin inhibits human platelet aggregation and activation.

Full Kinetin + Phenprocoumon answer

Can you take N-acetyl Cysteine (nac) with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full N-acetyl Cysteine (nac) + Phenprocoumon answer

Can you take Nattokinase with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Nattokinase might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.

Full Nattokinase + Phenprocoumon answer

Can you take Niacin with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, niacin may have additive effects when used with anticoagulant or antiplatelet drugs.

Full Niacin + Phenprocoumon answer

Can you take Octacosanol with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, octacosanol might inhibit platelet aggregation; however, clinical research suggests that this effect may not be clinically si...

Full Octacosanol + Phenprocoumon answer

Can you take Onion with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of anticoagulant or antiplatelet drugs with onion might increase the risk of bleeding.

Full Onion + Phenprocoumon answer

Can you take Oolong Tea with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, oolong tea might increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Oolong Tea + Phenprocoumon answer

Can you take Oregano with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full Oregano + Phenprocoumon answer

Can you take Oregon Grape with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Oregon grape might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full Oregon Grape + Phenprocoumon answer

Can you take Palm Oil with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, palm oil might decrease the effectiveness of antiplatelet or anticoagulant drugs.

Full Palm Oil + Phenprocoumon answer

Can you take Pantethine with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.

Full Pantethine + Phenprocoumon answer

Can you take Parsley with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full Parsley + Phenprocoumon answer

Can you take Pau D'arco with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full Pau D'arco + Phenprocoumon answer

Can you take Peony with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

Full Peony + Phenprocoumon answer

Can you take Phellodendron with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, phellodendron might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.

Full Phellodendron + Phenprocoumon answer

Can you take Plum with Phenprocoumon?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, plum juice might have antiplatelet effects.

Full Plum + Phenprocoumon answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Phenprocoumon is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Phenprocoumon, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Phenprocoumon sits in 3 interaction categories. Open any one to see what the group means:

Anticoagulant/Antiplatelet Drugs 202 ingredients

Blood-thinning medications. Supplements with their own effects on clotting or platelets can add up with these drugs and raise bleeding risk.

202 of the supplement ingredients on this page reach Phenprocoumon through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Phenprocoumon through this category.

Phenprocoumon (Marcoumar, Others) 2 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

2 of the supplement ingredients on this page reach Phenprocoumon through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Phenprocoumon

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Phenprocoumon.

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Pharmacist Counseling Corner

Phenprocoumon & Supplements: Common Questions

What supplements interact with Phenprocoumon?
More than you might expect — 219 in total, though they are far from equal: 4 are rated major, 190 moderate, and 25 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: St. John's Wort, Activated Charcoal, Danshen.
Which Phenprocoumon supplement interactions are the most serious?
Focus on the major group: St. John's Wort, Activated Charcoal, Danshen and Piracetam. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Phenprocoumon?
Usually yes — most people on Phenprocoumon can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Liquamar have the same supplement interactions as Phenprocoumon?
Yes — Liquamar all contain Phenprocoumon, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Phenprocoumon and my other medications?
This page covers Phenprocoumon against supplements and herbal ingredients. Checking Phenprocoumon against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 23, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.