Drug & supplement interaction

Bamboo + Pemetrexed

Pemetrexed brand names: Alimta, Pemfexy.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Bamboo and Pemetrexed in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Bamboo and Pemetrexed

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Pemetrexed and Bamboo in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Bamboo safety at a glance

Bamboo overall Use caution Properly cooked shoots are widely eaten, but supplement safety is not well studied and raw shoots can be toxic.
Pregnancy Avoid There is not enough safety data on bamboo supplements, so avoid concentrated forms during pregnancy.
Breastfeeding Use caution Safety of bamboo supplements while breastfeeding is unknown; avoid concentrated extracts unless cleared by your doctor.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Pemetrexed and Bamboo? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Pemetrexed

Interactions in our licensed database are recorded against drug classes, not just single drug names. Pemetrexed is filed under a single classification — organic anion transporter 3 (oat3) substrates. Bamboo has documented interactions with 1 drug class — the most serious being antithyroid drugs (moderate) — and none of Pemetrexed’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Bamboo Does Interact With Other Medications

Bamboo has 5 moderate known drug interactions in our database — Pemetrexed isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Bamboo

Covers the 2,830 medications we’ve checked against Bamboo. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Bamboo and Pemetrexed May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Swelling Additional detail

    Bamboo

    “Bamboo shoots are a source of cyanide glycosides. However, the hydrogen cyanide produced by the plant is eliminated during boiling, fermentation, or superheated steam drying of the shoots. During the rescue of a male who jumped into a well which was used for bamboo shoot pickling, cyanide poisoning occurred in 8 individuals.”

    Bamboo · Natural Medicines adverse-effect record, reported in cardiac arrest.

    2 sources cited
    1. 96875. Satya S, Bal LM, Singhal P, Naik SN. Bamboo shoot processing: food quality and safety aspect (a review). Trends in Food Sci. Technol. 2010;21(4):181-9. DOI
    2. 96874. Sang-A-Gad P, Guharat S, Wananukul W. A mass cyanide poisoning from pickling bamboo shoots. Clin Toxicol (Phila). 2011 Nov;49(9):834-9. PubMed

    Pemetrexed

    Listed in the ADVERSE REACTIONS section of the FDA label for Pemetrexed. Read the label on DailyMed ›

  • A skin rash Additional detail

    Bamboo

    “Topically, bamboo shoots have been reported to cause contact dermatitis in a 44-year-old female.”

    Bamboo · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 33540. Kitajima T. Contact allergy caused by bamboo shoots. Contact Dermatitis 1986;15(2):100-102. PubMed

    Pemetrexed

    Listed in the ADVERSE REACTIONS section of the FDA label for Pemetrexed. Read the label on DailyMed ›

Effects for Pemetrexed come from the ADVERSE REACTIONS section of its FDA label; effects for Bamboo come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Everything else you take

See Every Supplement That Interacts With Pemetrexed

This page covers Bamboo only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Pemetrexed page lists 4 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: African Wild Potato (moderate), Banderol (moderate), Caffeic Acid (moderate) and Quercetin (moderate).

By severity: 4 moderate.

From our pharmacist’s overview on the Pemetrexed page

“Every supplement on file for pemetrexed (Alimta, Pemfexy) works the same way. Each can slow how the kidneys pull the drug out of the blood, which would let it linger and build to higher levels than intended.”

Reviewed by 2 · Jul 18, 2026

Open the Pemetrexed interaction page

One more smart check

Taking Bamboo as Part of a Dietary Supplement Product? Check It for Interactions

We hold 536 real supplement products containing Bamboo, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Bamboo. Even though Bamboo itself has no known interaction with Pemetrexed, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Bamboo and Pemetrexed Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Bamboo
Top half

#379 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Pemetrexed
Top half

#728 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Bamboo reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Bamboo and Pemetrexed records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Bamboo

What is Bamboo?

Bamboo
  • Source of silica for hair, skin, and nails
  • Bone and joint support
  • General nutrition (cooked shoots as food)
  • Antioxidant support
  • Traditional digestive remedy

Bamboo is a giant grass whose shoots are eaten as food and whose leaves and silica-rich extracts are sold as supplements, often for hair, skin, nail, and bone support. Solid human evidence for these benefits is limited, and raw shoots must be properly cooked because they contain natural compounds that can release cyanide. Talk to a pharmacist or doctor before using bamboo supplements, especially if you have thyroid problems or are pregnant.

Poaceae · Shoots, leaves, and leaf extract (and silica-rich extracts) · Food (cooked shoots), capsules, tea, leaf extract, powder

An interaction check asks whether these two react with each other — it does not ask whether Bamboo is a good idea for someone in your situation. Here is what our Bamboo record says about it on its own.

Bamboo: dosing

There is no well-established standardized dose for bamboo supplements. Products vary widely in their form (leaf extract, silica extract, powder) and in how much active material they contain.If you choose to use a bamboo supplement, follow the directions on the product label and do not exceed the recommended amount.

From our Bamboo monograph — the full record covers uses, side effects and every documented interaction.

Read the full Bamboo monograph & all interactions
Medication

About Pemetrexed Injection

What Is Pemetrexed Injection Used For?

Brand names: Alimta, Pemfexy

Pemetrexed Injection is used for non-squamous non-small cell lung cancer (NSCLC) in several situations: as an initial treatment (combined with pembrolizumab and platinum chemotherapy, or with cisplatin alone), as a maintenance treatment after platinum-based chemotherapy, or as a single agent when the cancer has come back after prior chemotherapy. It is not used for squamous cell non-small cell lung cancer.

Pemetrexed Injection is also used, in combination with cisplatin, for the initial treatment of malignant pleural mesothelioma — a cancer of the lining of the lungs — in patients whose disease cannot be surgically removed or who are not good candidates for surgery.

Most-Reported Side Effects for Pemetrexed

From FAERS, the FDA’s public side-effect reporting system (37,889 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Malignant neoplasm progression 3,095 reports
Anemia 2,134 reports
Nausea 1,906 reports
Diarrhea 1,824 reports
Pancytopenia 1,773 reports
See full Pemetrexed Injection drug information
Keep checking

Other Drugs & Bamboo

Browse every other medication we’ve checked against Bamboo — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
5Moderate
0Minor
2,824No known interaction
Moderate

5 interactions

No interaction 2,824 drugs checked — show the list
Evidence & sources

Bamboo References

The 4 references that drive our Bamboo monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Chandra AK, Ghosh D, Mukhopadhyay S, et al. Effect of bamboo shoot, Bambusa arundinacea (Retz.) Willd. on thyroid status under conditions of varying iodine intake in rats. Indian J Exp Biol 2004;42(8):781-786.
  2. Kitajima T. Contact allergy caused by bamboo shoots. Contact Dermatitis 1986;15(2):100-102. PubMed
  3. Sang-A-Gad P, Guharat S, Wananukul W. A mass cyanide poisoning from pickling bamboo shoots. Clin Toxicol (Phila). 2011 Nov;49(9):834-9. PubMed
  4. Satya S, Bal LM, Singhal P, Naik SN. Bamboo shoot processing: food quality and safety aspect (a review). Trends in Food Sci. Technol. 2010;21(4):181-9. DOI

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Bamboo and Pemetrexed Together: Common Questions

Is it safe to take Bamboo with Pemetrexed?
We do not list a known interaction between Bamboo and Pemetrexed. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Bamboo and Pemetrexed have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Bamboo and Pemetrexed combination checked?
Interactions in our licensed database are recorded against drug classes. Pemetrexed is filed under 1 classification, and Bamboo has documented interactions with 1 drug class — none of Pemetrexed's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Bamboo interact with any other medications?
Yes. Bamboo has 5 documented drug interactions in our database — Pemetrexed is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Pemetrexed interact with any supplements?
Yes. Pemetrexed has documented interactions with 4 supplements in our database — Bamboo is not one of them. The Pemetrexed interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Pemetrexed and Bamboo?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.