Drug & supplement interaction

Blood Irradiation Therapy + Dapsone

Dapsone brand names: Dapsone, Avlosulfon, Aczone.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 13, 2026

The bottom line No known interaction

We found no known interaction between Blood Irradiation Therapy and Dapsone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Blood Irradiation Therapy and Dapsone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Dapsone and Blood Irradiation Therapy in our sources. This does not guarantee that the combination is completely free of risk — research on Blood Irradiation Therapy alongside specific medications may be limited.

Blood Irradiation Therapy is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Blood Irradiation Therapy safety at a glance

Blood Irradiation... overall Use caution This is an invasive procedure with infection and other risks, and it is not a proven treatment for most conditions.

Pregnancy Avoid Safety during pregnancy has not been established, so it is best avoided.

Breastfeeding Avoid There is no reliable safety data during breastfeeding, so avoid it.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Dapsone and Blood Irradiation Therapy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

How we checked

Why No Interaction Is Listed for Dapsone

Interactions in our licensed database are recorded against drug classes, not just single drug names. Dapsone is filed under 7 classifications — including antibiotic drugs, topical drugs, photosensitizing drugs. Blood Irradiation Therapy has documented interactions with 3 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate), antidiabetes drugs (moderate) and immunosuppressants (moderate) — and none of Dapsone’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Blood Irradiation Therapy Does Interact With Other Medications

Blood Irradiation Therapy has 327 moderate known drug interactions in our database — Dapsone isn’t one of them. If you take anything else, check it against the full list below.

Moderate 327 No known interaction 2,503 (incl. Dapsone)

Taking anything else?

Check Another of Your Medications Against Blood Irradiation Therapy

Covers the 2,830 medications we’ve checked against Blood Irradiation Therapy. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Blood Irradiation Therapy and Dapsone May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so having Blood Irradiation Therapy while taking the medicine can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

Hives Worth acting on Additional detail
Blood Irradiation Therapy
“There is currently a limited amount of information on the adverse effects of blood irradiation therapy. Case reports suggest that it may cause hypotension, urticaria, hypoglycemia, nasal bleeding, rigor, and bronchospasm.”

Blood Irradiation Therapy · Natural Medicines adverse-effect record, reported in hypotension.
1 source cited

27858. Marochkov AV, Doronin VA, Kravtsov NN. [Complications in ultraviolet irradiation of the blood]. Anesteziol Reanimatol 1990;(4):55-6.
“One case report suggests that blood irradiation therapy may cause urticaria.”

Blood Irradiation Therapy · Natural Medicines adverse-effect record, reported in urticaria.
1 source cited

27858. Marochkov AV, Doronin VA, Kravtsov NN. [Complications in ultraviolet irradiation of the blood]. Anesteziol Reanimatol 1990;(4):55-6.
Dapsone

Listed in the ADVERSE REACTIONS section of the FDA label for Dapsone. Read the label on DailyMed ›

Reported for Blood Irradiation Therapy but not commonly for Dapsone: wheezing, low blood sugar, low blood pressure and joint pain.

Effects for Dapsone come from the ADVERSE REACTIONS section of its FDA label; effects for Blood Irradiation Therapy come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 10,640 voluntary FDA FAERS reports for Dapsone that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Everything else you take

See Every Supplement That Interacts With Dapsone

This page covers Blood Irradiation Therapy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Dapsone page lists 215 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Para-aminobenzoic Acid (paba) (major) and Siberian Cocklebur (major).

By severity: 7 major · 167 moderate · 41 minor.

From our pharmacist’s overview on the Dapsone page

“Dapsone treats serious conditions, from dermatitis herpetiformis to leprosy, and its supplement list is one I'd want a patient to read closely rather than skim. Most entries touch how the body handles dapsone through the CYP3A4 enzyme, so grapefruit can raise its blood level while St.”

Reviewed by 2 · Jul 18, 2026

Open the Dapsone interaction page

How much people look this up

Where Blood Irradiation Therapy and Dapsone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Blood Irradiation Therapy

Steady interest

#1,191 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Dapsone

Top 10%

#175 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Blood Irradiation Therapy reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Blood Irradiation Therapy and Dapsone records this page draws on were last updated July 10, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Treatment approach

About Blood Irradiation Therapy

What is Blood Irradiation Therapy?

Chronic infections
Immune support
Fatigue and general wellness
Inflammatory conditions
Circulatory complaints

Blood Irradiation Therapy is a medical procedure—not a dietary supplement or herb—in which blood is exposed to ultraviolet or laser light, either outside the body and re-infused or by an intravenous light device. It is not approved by the U.S. FDA for treating any disease, and high-quality evidence supporting modern claims is very limited. If you are considering it, talk with a qualified physician and treat any clinic marketing it for serious illness with strong caution.

Whole blood (drawn and re-infused, or treated within the body) · Ultraviolet blood irradiation (UBI), intravenous laser blood irradiation, photodynamic procedures performed in clinics

An interaction check asks whether these two react with each other — it does not ask whether Blood Irradiation Therapy is a good idea for someone in your situation. Here is what our Blood Irradiation Therapy record says about it on its own.

Blood Irradiation Therapy: dosing

There is no standardized, scientifically established dose or protocol for Blood Irradiation Therapy. Clinics vary widely in the light source used, the amount of blood treated, the length of exposure, and how many sessions are recommended.Because this is a procedure rather than a pill or supplement, there is no label dose to follow.

From our Blood Irradiation Therapy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Blood Irradiation Therapy monograph & all interactions

Medication

About Dapsone

What Is Dapsone Used For?

Brand names: Dapsone, Avlosulfon, Aczone

Dapsone tablets are used to treat dermatitis herpetiformis (a chronic, intensely itchy blistering skin condition) and leprosy (all forms, except where proven resistance to dapsone exists). For leprosy, dapsone tablets are typically used in combination with other anti-leprosy medicines.

Aczone Gel (dapsone gel, 7.5%) and dapsone gel are indicated for the topical treatment of acne vulgaris in patients 9 years of age and older. This topical form is applied to the skin and is not used for leprosy or dermatitis herpetiformis.

Most-Reported Side Effects for Dapsone

From FAERS, the FDA’s public side-effect reporting system (10,640 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Nausea 487 reports

Methaemoglobinaemia 481 reports

Fatigue 477 reports

Fever 468 reports

Diarrhea 424 reports

See full Dapsone drug information

Keep checking

Other Drugs & Blood Irradiation Therapy

Browse every other medication we’ve checked against Blood Irradiation Therapy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

327Moderate

0Minor

2,502No known interaction

327 Moderate 2,502 No interaction

Moderate

327 interactions

Showing 60 of 327 moderate interactions — see all 327 on the Blood Irradiation Therapy page.

No interaction 2,502 drugs checked — show the list

We also checked Blood Irradiation Therapy against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,502 medications checked with no known interaction — see the full Blood Irradiation Therapy list.

See the full Blood Irradiation Therapy interactions page

See every supplement checked against Dapsone, ranked by severity

Evidence & sources

Blood Irradiation Therapy References

The 21 references that drive our Blood Irradiation Therapy monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Nikitin AV, Kashin AV, Karpukhina EP. [Correction of antioxidant defense in patients with bronchial asthma by the method of intravascular laser irradiation]. Probl Tuberk 1993;(3):46-7.
Bobrov VA, Sirenko IuN, Sychev OS, Malinovskaia IE. [Effects of laser irradiation of blood on electrical ventricular instability in patients with progressive angina pectoris]. Kardiologiia 1993;33(2):19-21.
Malinovskaia IE, Sirenko IuN, Shchumakov VA, et al. [Holter monitoring in assessing the efficacy of quantum hemotherapy in patients with unstable stenocardia]. Ter Arkh 1991;63(8):45-8.
Kazemi Khoo N, Iravani A, Arjmand M, et al. A metabolomic study on the effect of intravascular laser blood irradiation on type 2 diabetic patients. Lasers Med Sci 2013;28(6):1527-32. PubMed
Marochkov AV, Doronin VA, Kravtsov NN. [Complications in ultraviolet irradiation of the blood]. Anesteziol Reanimatol 1990;(4):55-6.
Neimark AI, Muzalevskaia NI, Neimark BA. [Prospects for preoperative low-intensity laser therapy in preventing postoperative thrombohemorrhagic complications in adenomectomy]. Urologiia 2002;(5):4-5.
Avrutskii MI, Katkovskii DG, Musikhin LV, et al. [[The use of intravenous low-intensity laser irradiation of the blood in the total complex of anesthesiological protection of patients against surgical stress]. Anesteziol Reanimatol 1991;(2):3-6.
Chepik EB, Shamanova MG, Medvedeva EV, et al. Photochemotherapy in the treatment of acute pneumonias]. Vestn Ross Akad Med Nauk 1994;(9):48-51.
Kuvshinchikova VN, Shmelev EI, Mishin VI. [Effectiveness of extracorporeal ultraviolet blood irradiation in treatment of chronic obstructive bronchitis in pulmonary tuberculosis]. Probl Tuberk 1998;(3):48-50.
Kuvshinchikova VN, Selina LG, Shmelev EI. [Effectiveness of extracorporeal ultraviolet blood irradiation in patients with chronic obstructive bronchitis]. Probl Tuberk 1998;(1):42-4.
Zvereva KV, Gladkova ND, Grunina EA, Logunov PL. [The choice of the method for intravascular laser therapy in rheumatoid arthritis]. Ter Arkh 1994;66(1):29-32.
Vakhrushev IaM, Shkatova EI. [Therapeutic efficiency of a combined use of low-intensity laser radiation and actovegin in gastroduodenal ulcers with inhibited cicatrix formation]. Ter Arkh 2003;75(9):86-9.
Opanasiuk ND, Degtiareva II, Skopichenko SV, et al. [The use of the immunomodulating action of intravascular laser irradiation of the blood in treating peptic ulcer patients]. Lik Sprava 1992;(1):66-8.
Subbotina LA, Radchenko SN, Golovkina OL, Bubeev IuA. [Hemoaggregation dynamics in human-operator during percutaneous laser blood irradiation]. Aviakosm Ekolog Med 2009;43(3):56-60.
Ovcharova AP. [The quantum gravitational therapy of myocarditis]. Lik Sprava 1999;(3):95-7.
Tkachenko IuIa, Kovalenko NN, Kogosova LS, et al. [The clinico-immunological characteristics of bronchial asthma patients undergoing autologous ultraviolet blood irradiation]. Lik Sprava 1993;(8):59-62.
Gorskova VA, Evmenov VF, Zaitseva TS, et al. [Effects of surgical intervention and intravascular irradiation of blood with helium-neon laser on the state humoral autoimmunity in oncological patients]. Khirurgiia (Mosk) 1991;(9):92-8.
Xiao X, Chu X, Ni J. [Effect of intravascular laser irradiation of blood and traditional Chinese medical therapy on immune function in senile cerebral infarction patients of kidney deficiency type]. Zhongguo Zhong Xi Yi Jie He Za Zhi 2000;20(4):264-6.
Nazarov IP, Popov AA, Mal'tseva MA, et al. [State of neuroendocrine systems and immunity in patients with burns]. Anesteziol Reanimatol 1994;(1):5-8.
Neimark AI, Muzalevskaia NI. [Low-intensity laser radiation in preoperative preparation of patients with benign prostatic hyperplasia]. Urologiia 2000;(1):11-5.
Chernushenko EF, Dziublik AI, Naida IV, et al. [Effects of intravascular laser irradiation of blood on the immune status of patients with bronchial obstructive diseases of the lungs]. Klin Med (Mosk) 1991;69(12):51-3.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Related: nutrient depletion

Dapsone Is Linked to Lower Levels of 7 Nutrients

Natural Medicines records Dapsone as a medicine that can lower these. This is not an interaction with Blood Irradiation Therapy — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:

Read the full Dapsone nutrient depletion report ›

Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.

Pharmacist Counseling Corner

Having Blood Irradiation Therapy While Taking Dapsone: Common Questions

Is it safe to have Blood Irradiation Therapy while taking Dapsone?

We do not list a known interaction between Blood Irradiation Therapy and Dapsone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Do Blood Irradiation Therapy and Dapsone have any of the same side effects?

Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.

How was the Blood Irradiation Therapy and Dapsone combination checked?

Interactions in our licensed database are recorded against drug classes. Dapsone is filed under 7 classifications, and Blood Irradiation Therapy has documented interactions with 3 drug classes — none of Dapsone's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.

Does Blood Irradiation Therapy interact with any other medications?

Yes. Blood Irradiation Therapy has 327 documented drug interactions in our database — Dapsone is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Does Dapsone interact with any supplements?

Yes. Dapsone has documented interactions with 215 supplements in our database — Blood Irradiation Therapy is not one of them. The Dapsone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Blood Irradiation Therapy monograph Uses, safety profile, and every drug interaction in one place Dapsone drug information The full plain-English guide to this medication Dapsone supplement interactions Every supplement checked against Dapsone, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 21 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Dapsone and Blood Irradiation Therapy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.