Drug & supplement interaction

Blood Irradiation Therapy + Estropipate

Estropipate brand names: Ogen, Ortho EST.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Blood Irradiation Therapy and Estropipate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Blood Irradiation Therapy and Estropipate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Estropipate and Blood Irradiation Therapy in our sources. This does not guarantee that the combination is completely free of risk — research on Blood Irradiation Therapy alongside specific medications may be limited.

Blood Irradiation Therapy is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Blood Irradiation Therapy safety at a glance

Blood Irradiation... overall Use caution This is an invasive procedure with infection and other risks, and it is not a proven treatment for most conditions.
Pregnancy Avoid Safety during pregnancy has not been established, so it is best avoided.
Breastfeeding Avoid There is no reliable safety data during breastfeeding, so avoid it.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Estropipate and Blood Irradiation Therapy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Estropipate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Estropipate is filed under 2 classifications — estrogens, oral drugs. Blood Irradiation Therapy has documented interactions with 3 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate), antidiabetes drugs (moderate) and immunosuppressants (moderate) — and none of Estropipate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Blood Irradiation Therapy Does Interact With Other Medications

Blood Irradiation Therapy has 327 moderate known drug interactions in our database — Estropipate isn’t one of them. If you take anything else, check it against the full list below.

Moderate 327 No known interaction 2,503 (incl. Estropipate)
Taking anything else?

Check Another of Your Medications Against Blood Irradiation Therapy

Covers the 2,830 medications we’ve checked against Blood Irradiation Therapy. Pick one to open its full report.

What to actually watch for

What Blood Irradiation Therapy Itself Has Been Linked To

This is not an interaction — nothing below involves Estropipate. It is the side-effect record for Blood Irradiation Therapy on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Blood Irradiation Therapy, this list is the first place to look. 4 entries are worth acting on rather than waiting out — marked below.

  • Low blood sugar Worth acting on Additional detail

    “There is currently a limited amount of information on the adverse effects of blood irradiation therapy. Case reports suggest that it may cause hypotension, urticaria, hypoglycemia, nasal bleeding, rigor, and bronchospasm.”

    Blood Irradiation Therapy · Natural Medicines adverse-effect record, reported in hypotension.

    1 source cited
    1. 27858. Marochkov AV, Doronin VA, Kravtsov NN. [Complications in ultraviolet irradiation of the blood]. Anesteziol Reanimatol 1990;(4):55-6.

    “One case report suggests that blood irradiation therapy may cause hypoglycemia. Preliminary clinical research shows that intravascular blood irradiation therapy reduces blood glucose levels in some people.”

    Blood Irradiation Therapy · Natural Medicines adverse-effect record, reported in hypoglycemia.

    2 sources cited
    1. 27858. Marochkov AV, Doronin VA, Kravtsov NN. [Complications in ultraviolet irradiation of the blood]. Anesteziol Reanimatol 1990;(4):55-6.
    2. 27857. Kazemi Khoo N, Iravani A, Arjmand M, et al. A metabolomic study on the effect of intravascular laser blood irradiation on type 2 diabetic patients. Lasers Med Sci 2013;28(6):1527-32. PubMed
  • Wheezing Worth acting on Additional detail

    Recorded for Blood Irradiation Therapy in the same Natural Medicines adverse-effect record shown under Low blood sugar above.

  • Hives Worth acting on Additional detail

    “One case report suggests that blood irradiation therapy may cause urticaria.”

    Blood Irradiation Therapy · Natural Medicines adverse-effect record, reported in urticaria.

    1 source cited
    1. 27858. Marochkov AV, Doronin VA, Kravtsov NN. [Complications in ultraviolet irradiation of the blood]. Anesteziol Reanimatol 1990;(4):55-6.
  • Bleeding or bruising Worth acting on Additional detail

    “Case reports suggest that blood irradiation therapy may cause nasal bleeding.”

    Blood Irradiation Therapy · Natural Medicines adverse-effect record, reported in bleeding.

    1 source cited
    1. 27858. Marochkov AV, Doronin VA, Kravtsov NN. [Complications in ultraviolet irradiation of the blood]. Anesteziol Reanimatol 1990;(4):55-6.
  • Low blood pressure Additional detail

    “Case reports suggest that blood irradiation therapy may cause hypotension.”

    Blood Irradiation Therapy · Natural Medicines adverse-effect record, reported in hypotension.

    1 source cited
    1. 27858. Marochkov AV, Doronin VA, Kravtsov NN. [Complications in ultraviolet irradiation of the blood]. Anesteziol Reanimatol 1990;(4):55-6.
  • Joint pain Additional detail

    “Case reports suggest that blood irradiation therapy may cause rigor. Preliminary clinical research suggests that intravascular blood irradiation therapy may exacerbate the inflammatory process in some patients with rheumatoid arthritis.”

    Blood Irradiation Therapy · Natural Medicines adverse-effect record, reported in rheumatoid arthritis (ra).

    2 sources cited
    1. 27858. Marochkov AV, Doronin VA, Kravtsov NN. [Complications in ultraviolet irradiation of the blood]. Anesteziol Reanimatol 1990;(4):55-6.
    2. 27867. Zvereva KV, Gladkova ND, Grunina EA, Logunov PL. [The choice of the method for intravascular laser therapy in rheumatoid arthritis]. Ter Arkh 1994;66(1):29-32.

Everything above comes from the Natural Medicines adverse-effect record for Blood Irradiation Therapy — expand a row for the licensed statement it rests on. We haven’t matched Estropipate to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Estropipate.

From our Q&A

Questions About Blood Irradiation Therapy or Estropipate

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Blood Irradiation Therapy or Estropipate, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Estropipate

This page covers Blood Irradiation Therapy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Estropipate page lists 77 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), Aletris (moderate), Alfalfa (moderate) and Androstenediol (moderate).

By severity: 2 major · 61 moderate · 14 minor.

From our pharmacist’s overview on the Estropipate page

“Estropipate (Ogen, Ortho EST) is an estrogen taken for menopause symptoms, and the women who use it are drawn to hormone-touted herbs, which fill this list of 77 ingredients, so it deserves genuine care. Grapefruit is one of two major-rated entries; it blocks the enzyme that clears estrogen, so levels and side effects can climb.”

Reviewed by 2 · Jul 18, 2026

Open the Estropipate interaction page

How much people look this up

Where Blood Irradiation Therapy and Estropipate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Blood Irradiation Therapy
Steady interest

#1,181 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Estropipate
Steady interest

#1,934 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Blood Irradiation Therapy reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Blood Irradiation Therapy and Estropipate records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Treatment approach

About Blood Irradiation Therapy

What is Blood Irradiation Therapy?

  • Chronic infections
  • Immune support
  • Fatigue and general wellness
  • Inflammatory conditions
  • Circulatory complaints

Blood Irradiation Therapy is a medical procedure—not a dietary supplement or herb—in which blood is exposed to ultraviolet or laser light, either outside the body and re-infused or by an intravenous light device. It is not approved by the U.S. FDA for treating any disease, and high-quality evidence supporting modern claims is very limited. If you are considering it, talk with a qualified physician and treat any clinic marketing it for serious illness with strong caution.

Whole blood (drawn and re-infused, or treated within the body) · Ultraviolet blood irradiation (UBI), intravenous laser blood irradiation, photodynamic procedures performed in clinics

An interaction check asks whether these two react with each other — it does not ask whether Blood Irradiation Therapy is a good idea for someone in your situation. Here is what our Blood Irradiation Therapy record says about it on its own.

Blood Irradiation Therapy: dosing

There is no standardized, scientifically established dose or protocol for Blood Irradiation Therapy. Clinics vary widely in the light source used, the amount of blood treated, the length of exposure, and how many sessions are recommended.Because this is a procedure rather than a pill or supplement, there is no label dose to follow.

From our Blood Irradiation Therapy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Blood Irradiation Therapy monograph & all interactions
Medication

About Estrogen

What Is Estrogen Used For?

Brand names: Ogen, Ortho EST

Based on the available product information, this Estrogen product is intended for external use on the skin — specifically the face, neck, or body. It is applied as part of a daily skincare routine.

For any specific medical concerns, the label recommends consulting a healthcare provider before use.

See full Estrogen drug information
Keep checking

Other Drugs & Blood Irradiation Therapy

Browse every other medication we’ve checked against Blood Irradiation Therapy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
327Moderate
0Minor
2,502No known interaction
327 Moderate 2,502 No interaction
Moderate

327 interactions

Showing 60 of 327 moderate interactions — see all 327 on the Blood Irradiation Therapy page.

No interaction 2,502 drugs checked — show the list

We also checked Blood Irradiation Therapy against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,502 medications checked with no known interaction — see the full Blood Irradiation Therapy list.

See the full Blood Irradiation Therapy interactions page
See every supplement checked against Estropipate, ranked by severity
Evidence & sources

Blood Irradiation Therapy References

The 21 references that drive our Blood Irradiation Therapy monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Nikitin AV, Kashin AV, Karpukhina EP. [Correction of antioxidant defense in patients with bronchial asthma by the method of intravascular laser irradiation]. Probl Tuberk 1993;(3):46-7.
  2. Bobrov VA, Sirenko IuN, Sychev OS, Malinovskaia IE. [Effects of laser irradiation of blood on electrical ventricular instability in patients with progressive angina pectoris]. Kardiologiia 1993;33(2):19-21.
  3. Malinovskaia IE, Sirenko IuN, Shchumakov VA, et al. [Holter monitoring in assessing the efficacy of quantum hemotherapy in patients with unstable stenocardia]. Ter Arkh 1991;63(8):45-8.
  4. Kazemi Khoo N, Iravani A, Arjmand M, et al. A metabolomic study on the effect of intravascular laser blood irradiation on type 2 diabetic patients. Lasers Med Sci 2013;28(6):1527-32. PubMed
  5. Marochkov AV, Doronin VA, Kravtsov NN. [Complications in ultraviolet irradiation of the blood]. Anesteziol Reanimatol 1990;(4):55-6.
  6. Neimark AI, Muzalevskaia NI, Neimark BA. [Prospects for preoperative low-intensity laser therapy in preventing postoperative thrombohemorrhagic complications in adenomectomy]. Urologiia 2002;(5):4-5.
  7. Avrutskii MI, Katkovskii DG, Musikhin LV, et al. [[The use of intravenous low-intensity laser irradiation of the blood in the total complex of anesthesiological protection of patients against surgical stress]. Anesteziol Reanimatol 1991;(2):3-6.
  8. Chepik EB, Shamanova MG, Medvedeva EV, et al. Photochemotherapy in the treatment of acute pneumonias]. Vestn Ross Akad Med Nauk 1994;(9):48-51.
  9. Kuvshinchikova VN, Shmelev EI, Mishin VI. [Effectiveness of extracorporeal ultraviolet blood irradiation in treatment of chronic obstructive bronchitis in pulmonary tuberculosis]. Probl Tuberk 1998;(3):48-50.
  10. Kuvshinchikova VN, Selina LG, Shmelev EI. [Effectiveness of extracorporeal ultraviolet blood irradiation in patients with chronic obstructive bronchitis]. Probl Tuberk 1998;(1):42-4.
  11. Zvereva KV, Gladkova ND, Grunina EA, Logunov PL. [The choice of the method for intravascular laser therapy in rheumatoid arthritis]. Ter Arkh 1994;66(1):29-32.
  12. Vakhrushev IaM, Shkatova EI. [Therapeutic efficiency of a combined use of low-intensity laser radiation and actovegin in gastroduodenal ulcers with inhibited cicatrix formation]. Ter Arkh 2003;75(9):86-9.
  13. Opanasiuk ND, Degtiareva II, Skopichenko SV, et al. [The use of the immunomodulating action of intravascular laser irradiation of the blood in treating peptic ulcer patients]. Lik Sprava 1992;(1):66-8.
  14. Subbotina LA, Radchenko SN, Golovkina OL, Bubeev IuA. [Hemoaggregation dynamics in human-operator during percutaneous laser blood irradiation]. Aviakosm Ekolog Med 2009;43(3):56-60.
  15. Ovcharova AP. [The quantum gravitational therapy of myocarditis]. Lik Sprava 1999;(3):95-7.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Having Blood Irradiation Therapy While Taking Estropipate: Common Questions

Is it safe to have Blood Irradiation Therapy while taking Estropipate?
We do not list a known interaction between Blood Irradiation Therapy and Estropipate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Blood Irradiation Therapy and Estropipate combination checked?
Interactions in our licensed database are recorded against drug classes. Estropipate is filed under 2 classifications, and Blood Irradiation Therapy has documented interactions with 3 drug classes — none of Estropipate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Blood Irradiation Therapy interact with any other medications?
Yes. Blood Irradiation Therapy has 327 documented drug interactions in our database — Estropipate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Estropipate interact with any supplements?
Yes. Estropipate has documented interactions with 77 supplements in our database — Blood Irradiation Therapy is not one of them. The Estropipate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Blood Irradiation Therapy monograph Uses, safety profile, and every drug interaction in one place Estrogen drug information The full plain-English guide to this medication Estropipate supplement interactions Every supplement checked against Estropipate, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 21 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Estropipate and Blood Irradiation Therapy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.