Drug & supplement interaction

Brewer's Yeast + Docusate Sodium, Phenolphthalein

Docusate Sodium, Phenolphthalein brand names: Correctol, Modane Plus.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Brewer's Yeast and Docusate Sodium, Phenolphthalein in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Brewer's Yeast and Docusate Sodium, Phenolphthalein

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Docusate Sodium, Phenolphthalein and Brewer's Yeast in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Brewer's Yeast safety at a glance

Brewer's Yeast overall Use caution Generally well tolerated in food amounts, but it can cause gas and may not be safe for people with weakened immune systems or certain conditions.
Pregnancy Use caution Likely fine in normal food amounts, but the safety of concentrated supplements during pregnancy is not well studied, so check with your provider.
Breastfeeding Use caution Food amounts are likely fine, but there is not enough information on supplement doses, so use caution and ask your provider.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Docusate Sodium, Phenolphthalein and Brewer's Yeast? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Docusate Sodium, Phenolphthalein

Interactions in our licensed database are recorded against drug classes, not just single drug names. Docusate Sodium, Phenolphthalein is filed under 2 classifications — stimulant laxatives, oral drugs. Brewer's Yeast has documented interactions with 4 drug classes — the most serious being monoamine oxidase inhibitors (maois) (major), antidiabetes drugs (moderate) and lithium (moderate) — and none of Docusate Sodium, Phenolphthalein’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Brewer's Yeast Does Interact With Other Medications

Brewer's Yeast has 9 major, 87 moderate, 40 minor known drug interactions in our database — Docusate Sodium, Phenolphthalein isn’t one of them. If you take anything else, check it against the full list below.

Major 9 Moderate 87 Minor 40 No known interaction 2,694 (incl. Docusate Sodium, Phenolphthalein)
Taking anything else?

Check Another of Your Medications Against Brewer's Yeast

Covers the 2,830 medications we’ve checked against Brewer's Yeast. Pick one to open its full report.

What to actually watch for

What Brewer's Yeast Itself Has Been Linked To

This is not an interaction — nothing below involves Docusate Sodium, Phenolphthalein. It is the side-effect record for Brewer's Yeast on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Brewer's Yeast, this list is the first place to look. 2 entries are worth acting on rather than waiting out — marked below.

  • Chest pain / Shortness of breath / Hives / An allergic reaction Worth acting on Additional detail

    “Allergic reactions to brewer's yeast can occur in hypersensitive individuals. Symptoms include itching, urticaria, local or general exanthemas, and Quincke's edema (2). Rarely, anaphylaxis may occur. In one case, a 33-year-old male experienced dyspnea, chest tightness, and throat tightness shortly after ingesting a few sips of craft beer brewed using brewer's yeast.”

    Brewer's Yeast · Natural Medicines adverse-effect record, reported in pruritus.

    2 sources cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    2. 111107. Mourey F, Decherf A, Jeanne JF, et al. Saccharomyces cerevisiae I-3856 in irritable bowel syndrome with predominant constipation. World J Gastroenterol 2022;28(22):2509-2522.
  • A severe allergic reaction Worth acting on Additional detail

    “Orally, brewer's yeast seems to be well tolerated in most patients when used short-term.

    Most Common Adverse Effects:

    Orally: Flatulence, migraine.

    Serious Adverse Effects (Rare):

    Orally: There is concern that brewer's yeast may cause fungemia in some people. It may also cause anaphylaxis in sensitive individuals.”

    Brewer's Yeast · Natural Medicines adverse-effect record, reported in flatulence.

  • Migraine Additional detail

    “Orally, brewer's yeast can cause migraine-like headaches in sensitive individuals (2).”

    Brewer's Yeast · Natural Medicines adverse-effect record, reported in migraine headache.

    1 source cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  • Bloating or gas Additional detail

    “Orally, brewer's yeast can cause intestinal discomfort and flatulence in hypersensitive individuals (2). Anal irritation and abdominal pain have been reported rarely.”

    Brewer's Yeast · Natural Medicines adverse-effect record, reported in flatulence.

    2 sources cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    2. 105170. Gayathri R, Aruna T, Malar S, Shilpa B, Dhanasekar KR. Efficacy of Saccharomyces cerevisiae CNCM I-3856 as an add-on therapy for irritable bowel syndrome. Int J Colorectal Dis. 2020;35(1):139-145. PubMed
  • Itching / Swelling Additional detail

    Recorded for Brewer's Yeast in the same Natural Medicines adverse-effect record shown under Chest pain / Shortness of breath / Hives / An allergic reaction above.

  • Stomach pain Additional detail

    Recorded for Brewer's Yeast in the same Natural Medicines adverse-effect record shown under Bloating or gas above.

Showing the 10 most notable of 11 recorded effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

Everything above comes from the Natural Medicines adverse-effect record for Brewer's Yeast — expand a row for the licensed statement it rests on. We haven’t matched Docusate Sodium, Phenolphthalein to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Docusate Sodium, Phenolphthalein.

From our Q&A

Questions About Brewer's Yeast or Docusate Sodium, Phenolphthalein

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Brewer's Yeast or Docusate Sodium, Phenolphthalein, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Docusate Sodium, Phenolphthalein

This page covers Brewer's Yeast only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Docusate Sodium, Phenolphthalein page lists 46 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Jalap (major), Oleander (major), Alder Buckthorn (moderate) and Aloe (moderate).

By severity: 3 major · 34 moderate · 9 minor.

From our pharmacist’s overview on the Docusate Sodium, Phenolphthalein page

“Correctol and Modane Plus pair docusate, a stool softener, with phenolphthalein, a stimulant laxative, and the pairings below deserve real caution. Of the 46 supplements and herbs on this list, 29 are plant laxatives that work the same way phenolphthalein does, so doubling up can drain fluid and potassium fast.”

Reviewed by 2 · Jul 18, 2026

Open the Docusate Sodium, Phenolphthalein interaction page

One more smart check

Taking Brewer's Yeast as Part of a Dietary Supplement Product? Check It for Interactions

We hold 126 real supplement products containing Brewer's Yeast, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Brewer's Yeast. Even though Brewer's Yeast itself has no known interaction with Docusate Sodium, Phenolphthalein, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Brewer's Yeast and Docusate Sodium, Phenolphthalein Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Brewer's Yeast
Top half

#581 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Docusate Sodium, Phenolphthalein
Top 5%

#82 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Brewer's Yeast reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Brewer's Yeast and Docusate Sodium, Phenolphthalein records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Brewer's Yeast

What is Brewer's Yeast?

Brewer's Yeast
  • Source of B vitamins
  • Diarrhea (certain types)
  • Cold and flu support
  • Digestive health
  • Acne and skin health
  • Blood sugar support

Brewer's yeast is a nutrient-rich fungus that provides B vitamins, protein, and minerals, and a related yeast product (S. boulardii) is used for some types of diarrhea. Most other health claims have limited or weak evidence. It is generally well tolerated as a food or supplement, but talk to your pharmacist or doctor before using it regularly, especially if you have a weakened immune system.

Saccharomyces cerevisiae · Saccharomycetaceae · Whole dried yeast cells (and their fermentation products) · Tablets, capsules, powder, flakes, liquid

An interaction check asks whether these two react with each other — it does not ask whether Brewer's Yeast is a good idea for someone in your situation. Here is what our Brewer's Yeast record says about it on its own.

Brewer's Yeast: dosing

There is no single official or proven dose for brewer's yeast. Products vary widely in their form (tablets, powder, flakes) and in how much yeast they contain.The best approach is to follow the directions on the product label and start with a lower amount to see how your stomach handles it. They can help you decide whether it is appropriate and whether a different, better-studied product (such as a specific probiotic) might be a better fit.

From our Brewer's Yeast monograph — the full record covers uses, side effects and every documented interaction.

Read the full Brewer's Yeast monograph & all interactions
Medication

About Bisacodyl

What Is Bisacodyl Used For?

Brand names: Correctol, Modane Plus

Bisacodyl is used for the temporary relief of occasional constipation and irregularity. Oral tablets (including Dulcolax Stimulant Laxative and Fleet tablets) generally produce a bowel movement within 6 to 12 hours.

Rectal suppositories (such as Dulcolax Laxative, Conlax, Avedana Gentle Laxative, and others) typically work within 15 minutes to 1 hour. The Fleet Enema (rectal) is also used for relief of fecal impaction (a severe blockage of stool) and for removal of residue after barium administration (a procedure used in certain imaging tests), and usually works within 5 to 20 minutes.

See full Bisacodyl drug information
Keep checking

Other Drugs & Brewer's Yeast

Browse every other medication we’ve checked against Brewer's Yeast — both the ones with a known interaction and the ones without. Select any drug for the full detail.

9Major
87Moderate
40Minor
2,693No known interaction
9 Major 87 Moderate 40 Minor 2,693 No interaction
Major

9 interactions

Moderate

87 interactions

Showing 60 of 87 moderate interactions — see all 87 on the Brewer's Yeast page.

Minor

40 interactions

No interaction 2,693 drugs checked — show the list

We also checked Brewer's Yeast against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,693 medications checked with no known interaction — see the full Brewer's Yeast list.

See the full Brewer's Yeast interactions page
See every supplement checked against Docusate Sodium, Phenolphthalein, ranked by severity
Evidence & sources

Brewer's Yeast References

The 6 references that drive our Brewer's Yeast monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Lewis SJ, Freedman AR. Review article: the use of biotherapeutic agents in the prevention and treatment of gastrointestinal disease. Aliment Pharmacol Ther 1998;12:807-22. PubMed
  3. Bahijiri, S. M., Mira, S. A., Mufti, A. M., and Ajabnoor, M. A. The effects of inorganic chromium and brewer's yeast supplementation on glucose tolerance, serum lipids and drug dosage in individuals with type 2 diabetes. Saudi.Med.J. 2000;21(9):831-837. DOI
  4. Schrauzer, G. N. and de, Vroey E. Effects of nutritional lithium supplementation on mood. A placebo-controlled study with former drug users. Biol.Trace Elem.Res. 1994;40(1):89-101. PubMed
  5. Gayathri R, Aruna T, Malar S, Shilpa B, Dhanasekar KR. Efficacy of Saccharomyces cerevisiae CNCM I-3856 as an add-on therapy for irritable bowel syndrome. Int J Colorectal Dis. 2020;35(1):139-145. PubMed
  6. Mourey F, Decherf A, Jeanne JF, et al. Saccharomyces cerevisiae I-3856 in irritable bowel syndrome with predominant constipation. World J Gastroenterol 2022;28(22):2509-2522.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Brewer's Yeast and Docusate Sodium, Phenolphthalein Together: Common Questions

Is it safe to take Brewer's Yeast with Docusate Sodium, Phenolphthalein?
We do not list a known interaction between Brewer's Yeast and Docusate Sodium, Phenolphthalein. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Brewer's Yeast and Docusate Sodium, Phenolphthalein combination checked?
Interactions in our licensed database are recorded against drug classes. Docusate Sodium, Phenolphthalein is filed under 2 classifications, and Brewer's Yeast has documented interactions with 4 drug classes — none of Docusate Sodium, Phenolphthalein's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Brewer's Yeast interact with any other medications?
Yes. Brewer's Yeast has 136 documented drug interactions in our database — Docusate Sodium, Phenolphthalein is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Docusate Sodium, Phenolphthalein interact with any supplements?
Yes. Docusate Sodium, Phenolphthalein has documented interactions with 46 supplements in our database — Brewer's Yeast is not one of them. The Docusate Sodium, Phenolphthalein interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Brewer's Yeast monograph Uses, safety profile, and every drug interaction in one place Bisacodyl drug information The full plain-English guide to this medication Docusate Sodium, Phenolphthalein supplement interactions Every supplement checked against Docusate Sodium, Phenolphthalein, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 6 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Docusate Sodium, Phenolphthalein and Brewer's Yeast?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.