Drug & supplement interaction

California Poppy + Dinutuximab

Dinutuximab brand name: Unituxin.

No Known Interaction
The bottom line No known interaction

We found no known interaction between California Poppy and Dinutuximab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

California Poppy and Dinutuximab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Dinutuximab and California Poppy in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

California Poppy safety at a glance

California Poppy overall Use caution Generally considered mild for short-term use, but human safety data are limited.
Pregnancy Avoid Not enough safety data; best avoided during pregnancy.
Breastfeeding Avoid Not enough safety data; best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Dinutuximab and California Poppy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
Keep it in perspective

California Poppy Does Interact With Other Medications

California Poppy has 248 moderate known drug interactions in our database — Dinutuximab isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against California Poppy

Covers the 2,830 medications we’ve checked against California Poppy. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests California Poppy and Dinutuximab May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Nausea Additional detail

    California Poppy

    “Orally, when used in combination with hawthorn and magnesium, California poppy has been reported to cause nausea. It is not clear if this effect is from California poppy, the other ingredients, or the combination.”

    California Poppy · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 12583. Hanus M, Lafon J, Mathieu M. Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate

    Dinutuximab

    Listed in the ADVERSE REACTIONS section of the FDA label for Dinutuximab. Read the label on DailyMed ›

Reported for California Poppy but not commonly for Dinutuximab: joint or muscle stiffness and tiredness.

Effects for Dinutuximab come from the ADVERSE REACTIONS section of its FDA label; effects for California Poppy come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 805 voluntary FDA FAERS reports for Dinutuximab that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

One more smart check

Taking California Poppy as Part of a Dietary Supplement Product? Check It for Interactions

We hold 345 real supplement products containing California Poppy, each one broken down to its full ingredient list — and combination products often carry several ingredients besides California Poppy. Even though California Poppy itself has no known interaction with Dinutuximab, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where California Poppy and Dinutuximab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement California Poppy
Top 25%

#300 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Dinutuximab
Top half

#1,414 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every California Poppy reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The California Poppy and Dinutuximab records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About California Poppy

What is California Poppy?

California Poppy
  • Anxiety and stress
  • Trouble sleeping (insomnia)
  • Mild aches and pains
  • Restlessness or nervous tension
  • Bedwetting in children (traditional use)

California poppy is a traditional herbal remedy used mainly for anxiety and sleep problems, often combined with other calming herbs. Human research is very limited, so its true benefits are not well proven. It is generally considered mild, but should be avoided during pregnancy and breastfeeding and used with caution by anyone taking sedating medicines.

Eschscholzia californica · Papaveraceae · Above-ground parts (flowers, leaves, stems) and roots · Tea, tincture, liquid extract, capsules, dried herb

An interaction check asks whether these two react with each other — it does not ask whether California Poppy is a good idea for someone in your situation. Here is what our California Poppy record says about it on its own.

California Poppy: dosing

There is no official, standardized dose for California poppy. Products vary widely in strength, and it is often part of herbal blends. The best approach is to follow the directions on the product label and not exceed the recommended amount.It is commonly taken in the evening when used for sleep, but timing and amount should be guided by the product and your own response.

From our California Poppy monograph — the full record covers uses, side effects and every documented interaction.

Read the full California Poppy monograph & all interactions
Medication

About Dinutuximab Injection

What Is Dinutuximab Injection Used For?

Brand name: Unituxin

Unituxin (dinutuximab) is used to treat high-risk neuroblastoma in pediatric patients. It is used as part of a combination regimen — alongside GM-CSF, IL-2, and 13-cis-retinoic acid — for children who have already responded at least partially to prior first-line treatment.

Unituxin is not used as a stand-alone treatment. It is given after patients have completed induction chemotherapy, surgery, high-dose consolidation chemotherapy with stem cell transplant, and radiation therapy.

Most-Reported Side Effects for Dinutuximab

From FAERS, the FDA’s public side-effect reporting system (805 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fever 167 reports
Neuroblastoma recurrent 83 reports
Abdominal pain 76 reports
Aspartate aminotransferase increased 63 reports
Alanine aminotransferase increased 61 reports
See full Dinutuximab Injection drug information
Keep checking

Other Drugs & California Poppy

Browse every other medication we’ve checked against California Poppy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
248Moderate
0Minor
2,581No known interaction
Moderate

248 interactions

Showing 60 of 248 moderate interactions — see all 248 on the California Poppy page.

No interaction 2,581 drugs checked — show the list
Evidence & sources

California Poppy References

The 3 references that drive our California Poppy monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Hanus M, Lafon J, Mathieu M. Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate
  2. Paul LD, Springer D, Staack RF, et al. Cytochrome P450 isoenzymes involved in rat liver microsomal metabolism of californine and protopine. Eur J Pharmacol 2004;485:69-79. PubMed
  3. Paul LD, Maurer HH. Studies on the metabolism and toxicological detection of the Eschscholtzia californica alkaloids californine and protopine in urine using gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2003;789:43-5

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking California Poppy and Dinutuximab Together: Common Questions

Is it safe to take California Poppy with Dinutuximab?
We do not list a known interaction between California Poppy and Dinutuximab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do California Poppy and Dinutuximab have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does California Poppy interact with any other medications?
Yes. California Poppy has 248 documented drug interactions in our database — Dinutuximab is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Dinutuximab and California Poppy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.