Carob + Fluvastatin
Fluvastatin brand names: Lescol, Lescol XL.
Carob has a minor interaction with Fluvastatin. Theoretically, carob might also impair the absorption of oral drugs.
Read the full interaction reportCarob and Fluvastatin
Here is the interaction we found between these two, with the evidence behind it.
ORAL DRUGS
Why this applies to Fluvastatin
Fluvastatin falls under ORAL DRUGS — the group Carob interacts with.
Laboratory research shows that carob, when consumed as part of the diet or used as a thickening agent in infant formula, reduces the absorption of certain minerals. Take carob 30-60 minutes after oral medications.
Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
Here's the gist for your cholesterol pill. Carob is rich in fiber and tannins, and those compounds can grab onto things in your gut and slow down how well they get absorbed. The concern with fluvastatin is the same idea: if you take a big serving of carob or carob gum right alongside your dose, less of the medicine might make it into your bloodstream. Over time, that could mean your LDL ('bad cholesterol') isn't lowered as much as expected.
I'll be honest though, this is a theoretical concern based on lab work, not a proven problem in people, and it's rated minor. The easy fix is timing. If you enjoy carob regularly, take your fluvastatin first and have the carob 30 to 60 minutes later. An occasional carob treat as food is unlikely to matter. Check with your pharmacist if you're unsure.
- Bosscher, D., Caillie-Bertrand, M., and Deelstra, H. Effect of thickening agents, based on soluble dietary fiber, on the availability of calcium, iron, and zinc from infant formulas. Nutrition 2001;17(7-8):614-618. PubMed
- Harmuth-Hoene, A. E. and Schelenz, R. Effect of dietary fiber on mineral absorption in growing rats. J Nutr 1980;110(9):1774-1784. PubMed
- Bosscher D, Van Caillie-Bertrand M, Van Cauwenbergh R, Deelstra H. Availabilities of calcium, iron, and zinc from dairy infant formulas is affected by soluble dietary fibers and modified starch fractions. Nutrition. 2003;19(7-8):641-5. PubMed
What These Ratings Mean
Every interaction above is graded three ways — here’s the key to each label.
Clinically significant. Avoid the combination, or use only under close professional supervision.
Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.
Generally not serious. Be aware of it and mention it to your pharmacist.
- LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
- ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
- UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
- AHigh-quality meta-analysis (quantitative systematic review).
- BCase-control study.
- CConsensus.
- DAnecdotal evidence.
These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.
Carob Also Interacts With Other Medications
Carob has 2,021 minor known drug interactions in our database — the Fluvastatin one above is one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Carob
We haven’t checked that one against Carob yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Carob. Pick one to open its full report.
See Every Supplement That Interacts With Fluvastatin
This page covers Carob only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Fluvastatin page lists 128 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Apple (major), Beer (major), Grapefruit (major) and Siberian Cocklebur (major).
By severity: 7 major · 97 moderate · 24 minor.
Taking Carob as Part of a Dietary Supplement Product? Check It for Interactions
We hold 161 real supplement products containing Carob, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Carob. Your product may carry other ingredients that interact with Fluvastatin too, on top of Carob — and those would not show on this page. Find your product and we’ll check every ingredient on its label:
Where Carob and Fluvastatin Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#777 of 1,452 supplements looked up here in the last 7 days
#928 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
About Carob
What is Carob?
- Diarrhea (especially in children)
- Cocoa/chocolate substitute
- Digestive upset
- Acid reflux/heartburn
- Source of dietary fiber
Carob is a Mediterranean tree whose pods are widely used as a caffeine-free, naturally sweet cocoa alternative and as a thickener (carob gum). It is mostly eaten as a food and is generally well tolerated, and carob pod preparations have some traditional and limited research use for diarrhea, but evidence for most medicinal claims is limited. Check with your pharmacist or doctor before using it as a treatment, especially for infants or children.
About Fluvastatin
What Is Fluvastatin Used For?
Brand names: Lescol, Lescol XL
Fluvastatin capsules are used alongside diet to lower total cholesterol, LDL cholesterol, triglycerides, and apolipoprotein B, and to raise HDL cholesterol in adults with primary hypercholesterolemia (high cholesterol) or mixed dyslipidemia (abnormal cholesterol and triglyceride levels). Fluvastatin capsules are also used in boys and girls aged 10–16 who have heterozygous familial hypercholesterolemia (an inherited form of high cholesterol) when diet alone has not worked. In adults with clinically evident coronary heart disease (CHD), fluvastatin capsules may reduce the risk of needing a coronary revascularization procedure (a procedure to restore blood flow, such as angioplasty) and can slow the progression of coronary atherosclerosis (plaque buildup in heart arteries).
Fluvastatin sodium extended-release tablets and Lescol XL (extended-release tablet) share similar uses: reducing LDL cholesterol in adults with primary hyperlipidemia, reducing LDL in adults and children aged 10 and older with heterozygous familial hypercholesterolemia who require the highest available dose, and reducing cardiovascular risk in adults with established coronary heart disease. Fluvastatin is always used together with a cholesterol-lowering diet, not as a replacement for one.
Other Drugs & Carob
Browse every other medication we’ve checked against Carob — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
2,021 interactions
- Diclofenac Sodium ›
- Diltiazem ›
- Theophylline ›
- Nifedipine ›
- Ibuprofen ›
- Salbutamol Sulfate ›
- Isosorbide Mononitrate ›
- Metronidazole ›
- Phendimetrazine Tartrate ›
- Phentermine ›
- Diphenhydramine ›
- Aspirin ›
- Hydrocortisone ›
- Methylphenidate ›
- Naproxen ›
- Nitroglycerin ›
- Pancrelipase (prescription Drug) ›
- Doxycycline ›
- Erythromycin ›
- Estradiol ›
- Lactulose ›
- Minocycline ›
- Propranolol ›
- Tetracycline ›
- Levothyroxine ›
- Potassium Chloride (prescription Drug) ›
- Ranitidine ›
- Amoxicillin ›
- Guaifenesin ›
- Hydrochlorothiazide ›
- Immune Globulin ›
- Norethindrone ›
- Verapamil ›
- Dicyclomine ›
- Epinephrine ›
- Fenofibrate ›
- Levonorgestrel ›
- Phenylpropanolamine ›
- Polyethylene Glycol 3350 ›
- Prednisone ›
- Quinidine ›
- Cyclosporine ›
- Dexamethasone ›
- Flurazepam ›
- Glyburide ›
- Glycopyrrolate ›
- Methyltestosterone ›
- Triazolam ›
- Zopiclone ›
- Bismuth Subsalicylate (otc Drug) ›
- Bupropion ›
- Chloroquine ›
- Ciprofloxacin ›
- Colchicine ›
- Dyphylline ›
- Fentanyl ›
- Flurbiprofen ›
- Isotretinoin ›
- Mesalamine ›
- Nicotine ›
Showing 60 of 2,021 minor interactions — see all 2,021 on the Carob page.
No interaction 808 drugs checked — show the list
We also checked Carob against these medications and found no known interaction in our sources. Open any page to confirm.
- Testosterone ›
- Tirzepatide ›
- Bendamustine ›
- Pegunigalsidase Alfa-iwxj ›
- Daptomycin ›
- Hexobarbitone ›
- Factor 7a ›
- Bentoquatam ›
- Tenecteplase ›
- Azelaic Acid ›
- Triptorelin ›
- Rocuronium ›
- Mitomycin C ›
- Halothane ›
- Caspofungin ›
- Insulin Degludec, Liraglutide ›
- Progesterone ›
- Rituximab ›
- Fam-trastuzumab, Deruxtecan-nxki ›
- Fish Oil Triglycerides ›
- Ciclesonide ›
- Etanercept ›
- Succinylcholine ›
- Flutemetamol F-18 ›
- Temsirolimus ›
- Mivacurium ›
- Paliperidone Palmitate ›
- Insulin Human, Sodium Chloride ›
- Satralizumab ›
- Rotigotine ›
- Docetaxel ›
- Etonogestrel, Ethinyl Estradiol ›
- Glofitamab-gxbm ›
- Sulfacetamide ›
- Nesiritide ›
- Anakinra ›
- Ferric Derisomaltose ›
- Adalimumab ›
- Bupivacaine, Meloxicam ›
- Afamelanotide Acetate ›
- Cemiplimab-rwlc ›
- Brodalumab ›
- Alglucosidase Alpha ›
- Amisulpride ›
- Enfortumab Vedotin-ejfv ›
- Sodium Pertechnetate ›
- Rapacuronium ›
- Abaloparatide ›
- Abametapir ›
- Abarelix ›
- Abatacept ›
- Aclidinium Bromide ›
- Adalimumab-adaz ›
- Adalimumab-adbm ›
- Adalimumab-afzb ›
- Adalimumab-atto ›
- Adalimumab-fkjp ›
- Adenosine (prescription Drug) ›
- Adenosine Phosphate (prescription Drug) ›
- Ado-trastuzumab Emtansine ›
Showing the 60 most looked-up of 808 medications checked with no known interaction — see the full Carob list.
Sources & How We Checked
Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference for vitamins, herbs and supplements — the basis for our interaction data.
- MedlinePlus, U.S. National Library of Medicine — NIH consumer drug information, used for the medication overviews.
- NIH Dietary Supplement Label Database (DSLD) — Official supplement product labels.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Fluvastatin Is Linked to Lower Levels of One Nutrient
Natural Medicines records Fluvastatin as a medicine that can lower these. This is not an interaction with Carob — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Fluvastatin nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Carob and Fluvastatin Together: Common Questions
Can you take Carob with Fluvastatin?
How serious is the Carob and Fluvastatin interaction?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.