Drug & supplement interaction

Chicory + Losartan Potassium

Losartan Potassium brand name: Cozaar.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Chicory and Losartan Potassium in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Chicory and Losartan Potassium

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Losartan Potassium and Chicory in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Chicory safety at a glance

Chicory overall Use caution Generally well tolerated in food amounts, but may cause gas and can trigger allergies in sensitive people.
Pregnancy Possibly Unsafe When used orally in excessive amounts. Chicory may induce menstruation or miscarriage. Read the full pregnancy detail
Breastfeeding Use caution There is not enough reliable safety information, so it is best to avoid medicinal amounts while breastfeeding.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Losartan Potassium and Chicory? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Losartan Potassium

Interactions in our licensed database are recorded against drug classes, not just single drug names. Losartan Potassium is filed under 7 classifications — including angiotensin receptor blockers (arbs), cytochrome p450 2c9 (cyp2c9) substrates, antihypertensive drugs. Chicory has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Losartan Potassium’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Chicory Does Interact With Other Medications

Chicory has 86 moderate known drug interactions in our database — Losartan Potassium isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Losartan Potassium)
Taking anything else?

Check Another of Your Medications Against Chicory

Covers the 2,830 medications we’ve checked against Chicory. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Chicory and Losartan Potassium May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. 3 of them are worth acting on rather than waiting out — marked below.

  • Shortness of breath / A severe allergic reaction Worth acting on reported in 5.2% of FDA reports for Losartan Potassium Additional detail

    Chicory

    “Occupational exposure to chicory may cause asthma and rhinoconjunctivitis. Dyspnea and anaphylaxis have also been reported in a patient with regular occupational exposure to chicory. This patient also experienced contact dermatitis and generalized pruritus.”

    Chicory · Natural Medicines adverse-effect record, reported in asthma.

    3 sources cited
    1. 41617. Nemery, B. and Demedts, M. Occupational asthma in a chicory grower. Lancet 3-25-1989;1(8639):672-673. PubMed
    2. 93648. Pirson F, Detry B, Pilette C. Occupational rhinoconjunctivitis and asthma caused by chicory and oral allergy syndrome associated with bet v 1-related protein. J Investig Allergol Clin Immunol 2009;19(4):306-10.
    3. 93649. Willi R, Pfab F, Huss-Marp J, et al. Contact anaphylaxis and protein contact dermatitis in a cook handling chicory leaves. Contact Dermatitis 2009;60(4):226-7. PubMed

    “Occupational exposure to chicory may cause allergic reactions. Dyspnea and anaphylaxis have also been reported in a patient with regular occupational exposure to chicory. This patient also experienced contact dermatitis and generalized pruritus.”

    Chicory · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 93649. Willi R, Pfab F, Huss-Marp J, et al. Contact anaphylaxis and protein contact dermatitis in a cook handling chicory leaves. Contact Dermatitis 2009;60(4):226-7. PubMed

    Losartan Potassium

    Listed in the ADVERSE REACTIONS section of the FDA label for Losartan Potassium, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

  • An allergic reaction Worth acting on Additional detail

    Chicory

    “Occupational exposure to chicory may cause skin rash, contact dermatitis, or generalized pruritus. The sesquiterpene lactones of the plant may be the allergens. Chicory may cause an allergic reaction in individuals sensitive to the Asterceae/Compositae family. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many other herbs.”

    Chicory · Natural Medicines adverse-effect record, reported in dermatitis.

    3 sources cited
    1. 41609. Friis, B., Hjorth, N., Vail, J. T., Jr., and Mitchell, J. C. Occupational contact dermatitis from Cichorium (chicory, endive) and Lactuca (lettuce). Contact Dermatitis 1975;1(5):311-313.
    2. 93649. Willi R, Pfab F, Huss-Marp J, et al. Contact anaphylaxis and protein contact dermatitis in a cook handling chicory leaves. Contact Dermatitis 2009;60(4):226-7. PubMed
    3. 25416. Cadot, P., Kochuyt, A. M., van Ree, R., and Ceuppens, J. L. Oral allergy syndrome to chicory associated with birch pollen allergy. Int.Arch.Allergy Immunol. 2003;131(1):19-24. PubMed

    Losartan Potassium

    Listed in the ADVERSE REACTIONS section of the FDA label for Losartan Potassium. Read the label on DailyMed ›

  • Itching / A skin rash Additional detail

    Chicory

    Recorded for Chicory in the same Natural Medicines adverse-effect record shown under Shortness of breath / A severe allergic reaction above.

    Losartan Potassium

    Listed in the ADVERSE REACTIONS section of the FDA label for Losartan Potassium. Read the label on DailyMed ›

  • Stomach pain Additional detail

    Chicory

    “Orally, chicory seems to be well tolerated.

    Most Common Adverse Effects:

    Orally: Abdominal pain, belching, bloating, and flatulence.”

    Chicory · Natural Medicines adverse-effect record, reported in flatulence.

    Losartan Potassium

    Listed in the ADVERSE REACTIONS section of the FDA label for Losartan Potassium. Read the label on DailyMed ›

Reported for Chicory but not commonly for Losartan Potassium: bloating or gas and wheezing.

Effects for Losartan Potassium come from the ADVERSE REACTIONS section of its FDA label; effects for Chicory come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 89,498 voluntary FDA FAERS reports for Losartan Potassium that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Chicory in Pregnancy & Breastfeeding

Pregnancy Possibly Unsafe

When used orally in excessive amounts. Chicory may induce menstruation or miscarriage.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Losartan Potassium Is Prescribed For, and What Chicory Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Losartan Potassium is a prescription medicine with approved uses on its FDA label. Chicory is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Losartan Potassium is prescribed for: Losartan tablets — available as branded Cozaar and several generic products — are used to treat high blood pressure (hypertension) in adults and children 6 years and older. Lowering blood pressure reduces the risk of strokes and heart attacks. Losartan tablets are also used to reduce the risk of stroke in people with high blood pressure who also have left ventricular hypertrophy (an enlarged left side of the heart). Note: evidence suggests this stroke-risk benefit may not apply to Black patients.

Read the rest of what Losartan Potassium is prescribed for

Losartan tablets are additionally approved to protect the kidneys in people with type 2 diabetes, high blood pressure, and signs of kidney damage (diabetic nephropathy). Arbli, the oral suspension form, shares these same approved uses.

Chicory has been studied for:

  • Hypertension studied, not established Chicory has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Chicory for hypertension

    Although there has been interest in using oral chicory for hypertension, there is insufficient reliable information about the clinical effects of chicory for this purpose.

  • Diabetes studied, not established Chicory has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Chicory for diabetes

    Although there has been interest in using oral chicory for diabetes, there is insufficient reliable information about the clinical effects of chicory for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Losartan Potassium on your own; if you are taking Chicory for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Chicory or Losartan Potassium

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Chicory or Losartan Potassium, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Losartan Potassium

This page covers Chicory only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Losartan Potassium page lists 253 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Grapefruit (major) and St. John's Wort (major).

By severity: 6 major · 205 moderate · 42 minor.

From our pharmacist’s overview on the Losartan Potassium page

“Losartan potassium (Cozaar) treats high blood pressure, and this is a list to respect, because six of its 253 supplement interactions carry a major rating. Most entries do one of two things.”

Reviewed by 2 · Jul 18, 2026

Open the Losartan Potassium interaction page

One more smart check

Taking Chicory as Part of a Dietary Supplement Product? Check It for Interactions

We hold 458 real supplement products containing Chicory, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Chicory. Even though Chicory itself has no known interaction with Losartan Potassium, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Chicory and Losartan Potassium Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Chicory
Top half

#397 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Losartan Potassium
Top 10

#6 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Chicory reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Chicory and Losartan Potassium records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Chicory

What is Chicory?

Chicory
  • Constipation and digestive health
  • Source of prebiotic fiber (inulin)
  • Coffee substitute
  • Liver and gallbladder support
  • Appetite and blood sugar (traditional)

Chicory is best known as a caffeine-free coffee substitute and as a source of inulin, a soluble prebiotic fiber that may support digestion and regularity. Strong human evidence for most other traditional uses (like liver, gallbladder, or skin conditions) is limited. It is generally well tolerated, but the inulin can cause gas and bloating, and people allergic to ragweed or related plants should be cautious.

Cichorium intybus · Asteraceae · Root and leaves (the root is the most common medicinal part) · Roasted root (coffee substitute), inulin fiber powder, capsules, tea, liquid extract

An interaction check asks whether these two react with each other — it does not ask whether Chicory is a good idea for someone in your situation. Here is what our Chicory record says about it on its own.

Chicory: dosing

There is no official standardized dose for chicory. The right amount depends on the form—roasted root for coffee, inulin fiber powder, capsules, or tea—and on the product's concentration.For inulin fiber, it is generally wise to start with a small amount and increase slowly to reduce gas and bloating, and to drink plenty of water.

From our Chicory monograph — the full record covers uses, side effects and every documented interaction.

Read the full Chicory monograph & all interactions
Medication

About Losartan

What Is Losartan Used For?

Brand name: Cozaar

Losartan tablets — available as branded Cozaar and several generic products — are used to treat high blood pressure (hypertension) in adults and children 6 years and older. Lowering blood pressure reduces the risk of strokes and heart attacks. Losartan tablets are also used to reduce the risk of stroke in people with high blood pressure who also have left ventricular hypertrophy (an enlarged left side of the heart). Note: evidence suggests this stroke-risk benefit may not apply to Black patients.

Losartan tablets are additionally approved to protect the kidneys in people with type 2 diabetes, high blood pressure, and signs of kidney damage (diabetic nephropathy). Arbli, the oral suspension form, shares these same approved uses.

Most-Reported Side Effects for Losartan Potassium

From FAERS, the FDA’s public side-effect reporting system (89,498 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 6,464 reports
Nausea 5,301 reports
Diarrhea 5,184 reports
Dyspnea 4,689 reports
Dizziness 4,429 reports
See full Losartan drug information
Keep checking

Other Drugs & Chicory

Browse every other medication we’ve checked against Chicory — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Chicory page.

No interaction 2,743 drugs checked — show the list

We also checked Chicory against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Chicory list.

See the full Chicory interactions page
See every supplement checked against Losartan Potassium, ranked by severity
Evidence & sources

Chicory References

The 13 references that drive our Chicory monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Stone-Dorshow T, Levitt MD. Gaseous response to ingestion of a poorly absorbed fructo-oligosaccharide sweetener. Am J Clin Nutr 1987;46:61-5. PubMed
  3. Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
  4. Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
  5. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  6. Cadot, P., Kochuyt, A. M., van Ree, R., and Ceuppens, J. L. Oral allergy syndrome to chicory associated with birch pollen allergy. Int.Arch.Allergy Immunol. 2003;131(1):19-24. PubMed
  7. Friis, B., Hjorth, N., Vail, J. T., Jr., and Mitchell, J. C. Occupational contact dermatitis from Cichorium (chicory, endive) and Lactuca (lettuce). Contact Dermatitis 1975;1(5):311-313.
  8. Nemery, B. and Demedts, M. Occupational asthma in a chicory grower. Lancet 3-25-1989;1(8639):672-673. PubMed
  9. Pirson F, Detry B, Pilette C. Occupational rhinoconjunctivitis and asthma caused by chicory and oral allergy syndrome associated with bet v 1-related protein. J Investig Allergol Clin Immunol 2009;19(4):306-10.
  10. Willi R, Pfab F, Huss-Marp J, et al. Contact anaphylaxis and protein contact dermatitis in a cook handling chicory leaves. Contact Dermatitis 2009;60(4):226-7. PubMed
  11. Street RA, Sidana J, Prinsloo G. Cichorium intybus: traditional uses, phytochemistry, pharmacology, and toxicology. Evid Based Complement Alternat Med 2013;2013:579319.
  12. Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc 2010;110(6):865-8. PubMed
  13. Devi Kt R, Sivalingam N. Cichorium intybus attenuates Streptozotocin-induced pancreatic ß-cell damage by inhibiting NF-?B activation and oxidative stress. J Appl Biomed 2020;18(2-3):70-9. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Chicory and Losartan Potassium Together: Common Questions

Is it safe to take Chicory with Losartan Potassium?
We do not list a known interaction between Chicory and Losartan Potassium. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Chicory and Losartan Potassium have any of the same side effects?
Yes — our sources link each of them separately to 6 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Are Chicory and Losartan Potassium used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Chicory in each. That is a conversation for your prescriber, especially if Losartan Potassium is being adjusted to a target.
How was the Chicory and Losartan Potassium combination checked?
Interactions in our licensed database are recorded against drug classes. Losartan Potassium is filed under 7 classifications, and Chicory has documented interactions with 1 drug class — none of Losartan Potassium's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Chicory interact with any other medications?
Yes. Chicory has 86 documented drug interactions in our database — Losartan Potassium is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Losartan Potassium interact with any supplements?
Yes. Losartan Potassium has documented interactions with 253 supplements in our database — Chicory is not one of them. The Losartan Potassium interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Chicory monograph Uses, safety profile, and every drug interaction in one place Losartan drug information The full plain-English guide to this medication Losartan Potassium supplement interactions Every supplement checked against Losartan Potassium, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 13 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Losartan Potassium and Chicory?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.