Coenzyme Q10 - Tricor (Fenofibrate) Interaction
Herbal: Coenzyme Q10
Also Known As: CoQ10
Drug: Fenofibrate
Brand names:
Tricor, Fenofibrate, Lipidil Micro, Lipidil Supra, Antara, Lofibra, Triglide, Lipidil EZ
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 08, 2025
Interaction Details
There were no interactions found between Fenofibrate and Coenzyme Q10. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Pharmacist Analysis
Although CoQ10 is considered relatively safe for most individuals, it does have some reported interactions that are important to be aware of.
This includes:
- Antihypertensives: Clinical research has shown that CoQ10 can significantly lower blood pressure but conflicting results have been reported.
- Warfarin: Research is conflicting but concomitant use of CoQ10 and warfarin might reduce the anticoagulant effects of warfarin.
- Alkylating Agents: Antioxidants such as CoQ10 might also protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy.
Outside of the interactions I've listed above, CoQ10 is generally considered safe to supplement with in most situations.
In fact, some individuals taking certain medications (e.g., 'Statins') may be recommended to take it.
If you have any questions about CoQ10 supplements, be sure to speak to your healthcare professional. We are always happy to answer questions on the matter as well!
- Dr. Brian Staiger, PharmDCoenzyme Q10 Overview
Fenofibrate Overview
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Fenofibrate is used with a low-fat diet, exercise, and sometimes with other medications to reduce the amounts of fatty substances such as cholesterol and triglycerides in the blood and to increase the amount of HDL (high-density lipoprotein; a type of fatty substance that decreases the risk of heart disease) in the blood. Build-up of cholesterol and fats along the walls of the arteries (a process known as atherosclerosis) decreases the blood flow and, therefore, the oxygen supply to the heart, brain, and other parts of the body. This increases the risk of heart disease, angina (chest pain), strokes, and heart attacks. Although fenofibrate decreases the levels of fatty substances in the blood, it has not been shown to decrease the risk of heart attacks or strokes. Fenofibrate is in a class of medications called antilipemic agents. It works by speeding the natural processes that remove cholesterol from the body.
Coenzyme Q10 - More Interactions
Coenzyme Q10 interacts with 195 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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