Drug & supplement interaction

Galbanum + diphenhydramine, calamine

diphenhydramine, calamine brand names: Caladryl cream, Caladryl lotion.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Galbanum and diphenhydramine, calamine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Galbanum and diphenhydramine, calamine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between diphenhydramine, calamine and Galbanum in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Galbanum safety at a glance

Galbanum overall Use caution Limited safety data exist, and essential oils can irritate skin or cause reactions if used incorrectly.
Pregnancy Avoid Not enough safety information is available, and some Ferula species are traditionally avoided in pregnancy.
Breastfeeding Avoid There is no reliable safety data, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining diphenhydramine, calamine and Galbanum? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for diphenhydramine, calamine

Interactions in our licensed database are recorded against drug classes, not just single drug names. diphenhydramine, calamine is filed under 2 classifications — cytochrome p450 2d6 (cyp2d6) inhibitors, topical drugs. Galbanum has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of diphenhydramine, calamine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Galbanum Does Interact With Other Medications

Galbanum has 86 moderate known drug interactions in our database — diphenhydramine, calamine isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. diphenhydramine, calamine)
Taking anything else?

Check Another of Your Medications Against Galbanum

Covers the 2,830 medications we’ve checked against Galbanum. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With diphenhydramine, calamine

This page covers Galbanum only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the diphenhydramine, calamine page lists 6 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Fever Bark (moderate), Iboga (moderate), Turpentine Oil (moderate) and Yohimbe (moderate).

By severity: 5 moderate · 1 minor.

From our pharmacist’s overview on the diphenhydramine, calamine page

“Yohimbe is the entry I would read first. Diphenhydramine, the itch-relieving antihistamine in Caladryl cream and lotion, blocks a liver enzyme called CYP2D6, and yohimbine, the active compound in yohimbe bark, needs that enzyme to leave the body, so its levels and side effects can climb.”

Reviewed by 2 · Jul 18, 2026

Open the diphenhydramine, calamine interaction page

One more smart check

Taking Galbanum as Part of a Dietary Supplement Product? Check It for Interactions

We hold 14 real supplement products containing Galbanum, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Galbanum. Even though Galbanum itself has no known interaction with diphenhydramine, calamine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Galbanum and diphenhydramine, calamine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Galbanum
Steady interest

#1,066 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication diphenhydramine, calamine
Top 10%

#242 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Galbanum reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Galbanum and diphenhydramine, calamine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Galbanum

What is Galbanum?

  • Aromatherapy and fragrance
  • Digestive complaints
  • Coughs and chest congestion
  • Skin and wound care (traditional)
  • Antimicrobial (traditional)

Galbanum is an aromatic gum resin from a Ferula plant, used mostly in perfumes, incense, and traditional remedies. There is very little solid human research to support any medical use, so it is best thought of as a fragrance and folk remedy rather than a proven treatment. If you want to use it for health reasons, talk with your pharmacist or doctor first.

Ferula gummosa · Apiaceae · Oleo-gum-resin and essential oil from the stems and roots · Essential oil, resin, incense, perfume ingredient, tincture

An interaction check asks whether these two react with each other — it does not ask whether Galbanum is a good idea for someone in your situation. Here is what our Galbanum record says about it on its own.

Galbanum: dosing

There is no established or standardized medicinal dose for galbanum. It has not been studied enough in humans to set safe, effective amounts.If you choose to use a galbanum product, follow the directions on the label exactly. Essential oils should be diluted properly and are generally meant for aromatherapy or topical use, not for swallowing.

From our Galbanum monograph — the full record covers uses, side effects and every documented interaction.

Read the full Galbanum monograph & all interactions
Keep checking

Other Drugs & Galbanum

Browse every other medication we’ve checked against Galbanum — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Galbanum page.

No interaction 2,743 drugs checked — show the list

We also checked Galbanum against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Galbanum list.

See the full Galbanum interactions page
See every supplement checked against diphenhydramine, calamine, ranked by severity
Evidence & sources

Galbanum References

The 1 references that drive our Galbanum monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Jalili-Nik M, Soukhtanloo M, Javanshir S, et al. Effects of ethanolic extract of Ferula gummosa oleo-resin in a rat model of streptozotocin-induced diabetes. Res Pharm Sci 2019;14(2):138-145. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Galbanum and diphenhydramine, calamine Together: Common Questions

Is it safe to take Galbanum with diphenhydramine, calamine?
We do not list a known interaction between Galbanum and diphenhydramine, calamine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Galbanum and diphenhydramine, calamine combination checked?
Interactions in our licensed database are recorded against drug classes. diphenhydramine, calamine is filed under 2 classifications, and Galbanum has documented interactions with 1 drug class — none of diphenhydramine, calamine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Galbanum interact with any other medications?
Yes. Galbanum has 86 documented drug interactions in our database — diphenhydramine, calamine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does diphenhydramine, calamine interact with any supplements?
Yes. diphenhydramine, calamine has documented interactions with 6 supplements in our database — Galbanum is not one of them. The diphenhydramine, calamine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Galbanum monograph Uses, safety profile, and every drug interaction in one place diphenhydramine, calamine supplement interactions Every supplement checked against diphenhydramine, calamine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About diphenhydramine, calamine and Galbanum?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.