Drug & supplement interaction

Galbanum + Glyburide

Glyburide brand names: Diabeta, Micronase, Glynase, Glycron, Micronized, and others.

Moderate Interaction
The bottom line Moderate

Galbanum has a moderate interaction with Glyburide. Theoretically, taking galbanum with antidiabetes drugs might increase the risk of hypoglycemia.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Galbanum and Glyburide

Here is the interaction we found between these two, with the evidence behind it.

Moderate

ANTIDIABETES DRUGS

Why this applies to Glyburide

Glyburide falls under ANTIDIABETES DRUGS — the group Galbanum interacts with.

Theoretically, taking galbanum with antidiabetes drugs might increase the risk of hypoglycemia.
In an animal diabetic model, galbanum resin reduces levels of fasting blood glucose at doses of 100 mg/kg, but not 400 mg/kg. This has not been shown in human research.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the gist: glyburide already lowers your blood sugar by nudging your pancreas to release more insulin. In one animal study, galbanum resin also brought fasting blood sugar down a bit. So the theoretical worry is that stacking the two could push your sugar too low.

If that happened, you might feel shaky, sweaty, dizzy, confused, or unusually hungry, the classic signs of low blood sugar. That said, I want to be honest about the evidence: this is based only on lab and animal work, with nothing shown in people, and the effect didn't even hold at higher doses. The small amounts in perfume or incense are very unlikely to matter. If you're thinking about a galbanum supplement, check in with your pharmacist or doctor first and keep an eye on your readings.

References
  1. Jalili-Nik M, Soukhtanloo M, Javanshir S, et al. Effects of ethanolic extract of Ferula gummosa oleo-resin in a rat model of streptozotocin-induced diabetes. Res Pharm Sci 2019;14(2):138-145. PubMed

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Galbanum Also Interacts With Other Medications

Galbanum has 85 moderate known drug interactions in our database — the Glyburide one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Galbanum

Covers the 2,830 medications we’ve checked against Galbanum. Pick one to open its full report.

From our Q&A

Questions About Galbanum or Glyburide

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Galbanum or Glyburide, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Glyburide

This page covers Galbanum only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Glyburide page lists 331 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Apple (major), Beer (major), Grapefruit (major) and Siberian Cocklebur (major).

By severity: 7 major · 279 moderate · 45 minor.

Open the Glyburide interaction page

One more smart check

Taking Galbanum as Part of a Dietary Supplement Product? Check It for Interactions

We hold 14 real supplement products containing Galbanum, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Galbanum. Your product may carry other ingredients that interact with Glyburide too, on top of Galbanum — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Galbanum and Glyburide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Galbanum
Steady interest

#1,146 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Glyburide
Top half

#785 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Galbanum

What is Galbanum?

  • Aromatherapy and fragrance
  • Digestive complaints
  • Coughs and chest congestion
  • Skin and wound care (traditional)
  • Antimicrobial (traditional)

Galbanum is an aromatic gum resin from a Ferula plant, used mostly in perfumes, incense, and traditional remedies. There is very little solid human research to support any medical use, so it is best thought of as a fragrance and folk remedy rather than a proven treatment. If you want to use it for health reasons, talk with your pharmacist or doctor first.

Read the full Galbanum monograph & all interactions
Medication

About Glyburide

What Is Glyburide Used For?

Brand names: Diabeta, Micronase, Glynase, Glycron, Micronized, Glynase PresTab, Albert Glyburide

Glyburide tablets are used alongside diet and exercise to help control blood sugar in adults with type 2 diabetes. It is not for type 1 diabetes or diabetic ketoacidosis (a serious complication where the body produces dangerous levels of acids called ketones).

Glyburide may be used alone or combined with metformin when metformin alone is not enough. It can also be used to help transition patients who are moving from insulin or other diabetes pills to a new regimen, under a doctor's guidance.

See full Glyburide drug information
Keep checking

Other Drugs & Galbanum

Browse every other medication we’ve checked against Galbanum — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
85Moderate
0Minor
2,744No known interaction
Moderate

85 interactions

Showing 60 of 85 moderate interactions — see all 85 on the Galbanum page.

No interaction 2,744 drugs checked — show the list
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Galbanum and Glyburide Together: Common Questions

Can you take Galbanum with Glyburide?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Galbanum and Glyburide interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.