Ginkgo + Rucaparib Camsylate
Rucaparib Camsylate brand name: Rubraca.
Ginkgo has a moderate interaction with Rucaparib Camsylate. Theoretically, taking ginkgo with P-glycoprotein substrates might increase the levels and adverse effects of these substrates.
Read the full interaction reportGinkgo and Rucaparib Camsylate
Here is the interaction we found between these two, with the evidence behind it.
P-GLYCOPROTEIN SUBSTRATES
Why this applies to Rucaparib Camsylate
Rucaparib Camsylate falls under P-GLYCOPROTEIN SUBSTRATES — the group Ginkgo interacts with.
A small clinical study in healthy volunteers shows that using ginkgo leaf extract 120 mg orally three times daily for 14 days can increase levels of the P-glycoprotein substrate, talinolol, by 36% in healthy male individuals. However, single doses of ginkgo do not have the same effect.
Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
Here's the gist for Rubraca (rucaparib). Your body uses a kind of cellular bouncer called P-glycoprotein to push certain drugs back out and keep their levels in check. Ginkgo may slow that bouncer down a bit. Since rucaparib is carried by this same system, taking ginkgo regularly could let a little more rucaparib build up in your body.
If that happens, you might notice more of rucaparib's usual side effects, like nausea, fatigue, low blood counts, or changes in lab tests. Keep in mind this is mostly theoretical, based on a small study using a different drug, and one-time ginkgo doses didn't cause it. Still, with a cancer medicine like this, please check with your oncology team or pharmacist before adding ginkgo.
- Fan, L., Tao, G. Y., Wang, G., Chen, Y., Zhang, W., He, Y. J., Li, Q., Lei, H. P., Jiang, F., Hu, D. L., Huang, Y. F., and Zhou, H. H. Effects of Ginkgo biloba extract ingestion on the pharmacokinetics of talinolol in healthy Chinese volunteers. Ann Phar PubMed
What These Ratings Mean
Every interaction above is graded three ways — here’s the key to each label.
Clinically significant. Avoid the combination, or use only under close professional supervision.
Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.
Generally not serious. Be aware of it and mention it to your pharmacist.
- LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
- ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
- UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
- AHigh-quality meta-analysis (quantitative systematic review).
- BCase-control study.
- CConsensus.
- DAnecdotal evidence.
These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.
Ginkgo Also Interacts With Other Medications
Ginkgo has 1 major, 1,264 moderate known drug interactions in our database — the Rucaparib Camsylate one above is one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Ginkgo
We haven’t checked that one against Ginkgo yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Ginkgo. Pick one to open its full report.
Questions About Ginkgo or Rucaparib Camsylate
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Ginkgo or Rucaparib Camsylate, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
- Can I Take Ginkgo With Apixaban (Eliquis) and Atorvastatin? ›
- Does Lisinopril Interact With Ginkgo Biloba? ›
- Supplements for Leg Circulation Safe With Citalopram and Lisinopril ›
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Rucaparib Camsylate
This page covers Ginkgo only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Rucaparib Camsylate page lists 105 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), St. John's Wort (major), 1,3-dmaa (moderate), Acacia Rigidula (moderate) and Active Hexose Correlated Compound (ahcc) (moderate).
By severity: 2 major · 78 moderate · 25 minor.
Taking Ginkgo as Part of a Dietary Supplement Product? Check It for Interactions
We hold 4,399 real supplement products containing Ginkgo, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Ginkgo. Your product may carry other ingredients that interact with Rucaparib Camsylate too, on top of Ginkgo — and those would not show on this page. Find your product and we’ll check every ingredient on its label:
Where Ginkgo and Rucaparib Camsylate Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#60 of 1,452 supplements looked up here in the last 7 days
#825 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
About Ginkgo
What is Ginkgo?
- Memory and cognitive support
- Age-related mental decline
- Circulation problems
- Tinnitus (ringing in the ears)
- Dizziness or vertigo
Ginkgo is one of the world's most popular herbal supplements, mostly taken to support memory and circulation. The evidence for these uses is mixed and generally weak, and it is not proven to prevent memory loss or dementia. It is usually well tolerated in healthy adults, but it can thin the blood, so talk to your pharmacist or doctor before using it.
About Rucaparib
What Is Rucaparib Used For?
Brand name: Rubraca
Rubraca (rucaparib) is used for two types of cancer in adults who carry a harmful BRCA gene mutation (either inherited or found in the tumor). First, it is used as maintenance treatment — meaning ongoing treatment to keep cancer from coming back — in people with recurrent epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer who responded (fully or partially) to platinum-based chemotherapy.
Second, Rubraca treats metastatic castration-resistant prostate cancer (advanced prostate cancer that has stopped responding to hormone-lowering treatment) in adults who have already received androgen receptor-directed therapy. Patients must be tested with an FDA-approved companion diagnostic to confirm the BRCA mutation before starting Rubraca for prostate cancer.
Other Drugs & Ginkgo
Browse every other medication we’ve checked against Ginkgo — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
1 interaction
1,264 interactions
- Diclofenac Sodium ›
- Diltiazem ›
- Theophylline ›
- Nifedipine ›
- Ibuprofen ›
- Metronidazole ›
- Diphenhydramine ›
- Aspirin ›
- Hydrocortisone ›
- Insulin (rdna) ›
- Methylphenidate ›
- Naproxen ›
- Doxycycline ›
- Erythromycin ›
- Estradiol ›
- Minocycline ›
- Propranolol ›
- Tetracycline ›
- Lidocaine ›
- Ranitidine ›
- Amoxicillin ›
- Norethindrone ›
- Testosterone ›
- Verapamil ›
- Levonorgestrel ›
- Prednisone ›
- Quinidine ›
- Cyclosporine ›
- Dexamethasone ›
- Glyburide ›
- Insulin (pork) ›
- Triazolam ›
- Zopiclone ›
- Bupropion ›
- Chloroquine ›
- Ciprofloxacin ›
- Colchicine ›
- Fentanyl ›
- Flurbiprofen ›
- Oxybutynin ›
- Oxycodone ›
- Penicillin V Potassium ›
- Phenytoin ›
- Prednisolone ›
- Tacrolimus ›
- Temazepam ›
- Triamcinolone ›
- Amphotericin B ›
- Ampicillin ›
- Apomorphine ›
- Budesonide ›
- Carbamazepine ›
- Ceftazidime ›
- Clindamycin ›
- Dextromethorphan ›
- Diclofenac Potassium ›
- Dipyridamole ›
- Doxorubicin ›
- Fluticasone ›
- Formoterol ›
Showing 60 of 1,264 moderate interactions — see all 1,264 on the Ginkgo page.
No interaction 1,564 drugs checked — show the list
We also checked Ginkgo against these medications and found no known interaction in our sources. Open any page to confirm.
- Levothyroxine ›
- Rosuvastatin ›
- Escitalopram ›
- Docusate ›
- Hydroxyurea ›
- Methamphetamine ›
- Sumatriptan ›
- Lisdexamfetamine ›
- Lisinopril ›
- Pregabalin ›
- Azithromycin ›
- Dextroamphetamine ›
- Isotretinoin ›
- Methylene Blue ›
- Levothyroxine, Liothyronine ›
- Cyclopentolate ›
- Candesartan Cilexetil ›
- Mannitol ›
- Roxithromycin ›
- Acetaminophen, Dextromethorphan, Doxylamine ›
- Pegunigalsidase Alfa-iwxj ›
- Daptomycin ›
- Hexobarbitone ›
- Levothyroxine Sodium ›
- Spironolactone ›
- Ezetimibe ›
- Thyroid Hormone ›
- Factor 7a ›
- Mitomycin ›
- Minoxidil ›
- Azelaic Acid ›
- Lenvatinib ›
- Phenylephrine ›
- Hethylphenidate Hcl ›
- Vancomycin ›
- Triptorelin ›
- Hydroxychloroquine ›
- Bentoquatam ›
- Dirithromycin ›
- Pizotifen ›
- Procainamide ›
- Dextrothyroxine ›
- Tocainide ›
- Rocuronium ›
- Lomustine ›
- Hydrochlorothiazide ›
- Flecainide ›
- Telmisartan ›
- Amphetamine Aspartate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate ›
- Mitomycin C ›
- Digitoxin ›
- Hydrochlorothiazide, Lisinopril ›
- Chenodiol ›
- Succimer ›
- Halothane ›
- Gestodene ›
- Desflurane ›
- Salbutamol Sulfate ›
- Niacin (prescription Drug) ›
- Caspofungin ›
Showing the 60 most looked-up of 1,564 medications checked with no known interaction — see the full Ginkgo list.
Sources & How We Checked
Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference for vitamins, herbs and supplements — the basis for our interaction data.
- MedlinePlus, U.S. National Library of Medicine — NIH consumer drug information, used for the medication overviews.
- NIH Dietary Supplement Label Database (DSLD) — Official supplement product labels.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Taking Ginkgo and Rucaparib Camsylate Together: Common Questions
Can you take Ginkgo with Rucaparib Camsylate?
How serious is the Ginkgo and Rucaparib Camsylate interaction?
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