Drug & supplement interaction

Goldenrod + Elbasvir, Grazoprevir

Elbasvir, Grazoprevir brand name: Zepatier.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Goldenrod and Elbasvir, Grazoprevir in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Goldenrod and Elbasvir, Grazoprevir

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Elbasvir, Grazoprevir and Goldenrod in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Goldenrod safety at a glance

Goldenrod overall Use caution Often well tolerated short-term, but human safety data are limited and allergy is possible.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Not enough safety information, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Elbasvir, Grazoprevir and Goldenrod? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Elbasvir, Grazoprevir

Interactions in our licensed database are recorded against drug classes, not just single drug names. Elbasvir, Grazoprevir is filed under 4 classifications — including organic anion transporter 3 (oat3) substrates, organic anion transporter 1 (oat1) substrates, cytochrome p450 3a4 (cyp3a4) substrates. Goldenrod has documented interactions with 1 drug class — the most serious being diuretic drugs (moderate) — and none of Elbasvir, Grazoprevir’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Goldenrod Does Interact With Other Medications

Goldenrod has 75 moderate known drug interactions in our database — Elbasvir, Grazoprevir isn’t one of them. If you take anything else, check it against the full list below.

Moderate 75 No known interaction 2,755 (incl. Elbasvir, Grazoprevir)
Taking anything else?

Check Another of Your Medications Against Goldenrod

Covers the 2,830 medications we’ve checked against Goldenrod. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Goldenrod and Elbasvir, Grazoprevir May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • A skin rash Additional detail

    Goldenrod

    “Topically, goldenrod has been reported to cause allergic contact dermatitis. Environmental exposure to goldenrod has been reported to cause an allergic reaction involving rhinoconjunctivitis and bronchial asthma in one case report.”

    Goldenrod · Natural Medicines adverse-effect record, reported in asthma.

    1 source cited
    1. 52558. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI

    Elbasvir, Grazoprevir

    Listed in the ADVERSE REACTIONS section of the FDA label for Elbasvir, Grazoprevir. Read the label on DailyMed ›

Reported for Goldenrod but not commonly for Elbasvir, Grazoprevir: an allergic reaction and wheezing.

Effects for Elbasvir, Grazoprevir come from the ADVERSE REACTIONS section of its FDA label; effects for Goldenrod come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 4,243 voluntary FDA FAERS reports for Elbasvir, Grazoprevir that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Everything else you take

See Every Supplement That Interacts With Elbasvir, Grazoprevir

This page covers Goldenrod only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Elbasvir, Grazoprevir page lists 140 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 96 moderate · 41 minor.

From our pharmacist’s overview on the Elbasvir, Grazoprevir page

“Zepatier (elbasvir and grazoprevir) is a fixed-course hepatitis C cure, and success depends on holding steady drug levels through every week of treatment, so this list deserves genuine care. Three of the 140 ingredients on file rate major.”

Reviewed by 2 · Jul 18, 2026

Open the Elbasvir, Grazoprevir interaction page

One more smart check

Taking Goldenrod as Part of a Dietary Supplement Product? Check It for Interactions

We hold 83 real supplement products containing Goldenrod, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Goldenrod. Even though Goldenrod itself has no known interaction with Elbasvir, Grazoprevir, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Goldenrod and Elbasvir, Grazoprevir Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Goldenrod
Top half

#443 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Elbasvir, Grazoprevir
Steady interest

#2,630 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Goldenrod reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Goldenrod and Elbasvir, Grazoprevir records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Goldenrod

What is Goldenrod?

  • Urinary tract health
  • Mild bladder or kidney support
  • Inflammation
  • Sore throat and mouth rinse
  • Wound care (traditional)

Goldenrod is a flowering plant traditionally used as an herbal diuretic and for urinary tract health. Human evidence is limited, and while it is generally well tolerated, people with certain allergies, kidney problems, or who are pregnant or breastfeeding should be cautious. Talk with a pharmacist or doctor before using it.

Solidago virgaurea · Asteraceae · Aerial parts (flowers, leaves, and stems) · Tea, tincture, liquid extract, capsules, dried herb

An interaction check asks whether these two react with each other — it does not ask whether Goldenrod is a good idea for someone in your situation. Here is what our Goldenrod record says about it on its own.

Goldenrod: dosing

There is no well-established standardized dose for goldenrod, and the right amount can vary widely depending on the product, the species used, and the form (tea, tincture, or capsule).Because of this, the best approach is to follow the directions on the product label and not exceed the recommended amount.

From our Goldenrod monograph — the full record covers uses, side effects and every documented interaction.

Read the full Goldenrod monograph & all interactions
Medication

About Elbasvir and Grazoprevir

What Is Elbasvir and Grazoprevir Used For?

Brand name: Zepatier

Zepatier is used to treat chronic hepatitis C virus (HCV) genotype 1 or genotype 4 infection in adults and children 12 years of age and older (or weighing at least 30 kg). It works against both the most common strain of HCV (genotype 1) and genotype 4.

Depending on the specific genotype, prior treatment history, and certain viral characteristics, Zepatier may be prescribed alone or combined with another antiviral medicine called ribavirin. Your prescriber will determine the right regimen and duration for your situation.

See full Elbasvir and Grazoprevir drug information
Keep checking

Other Drugs & Goldenrod

Browse every other medication we’ve checked against Goldenrod — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
75Moderate
0Minor
2,754No known interaction
75 Moderate 2,754 No interaction
Moderate

75 interactions

Showing 60 of 75 moderate interactions — see all 75 on the Goldenrod page.

No interaction 2,754 drugs checked — show the list

We also checked Goldenrod against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,754 medications checked with no known interaction — see the full Goldenrod list.

See the full Goldenrod interactions page
See every supplement checked against Elbasvir, Grazoprevir, ranked by severity
Evidence & sources

Goldenrod References

The 6 references that drive our Goldenrod monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  2. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
  3. Chodera, A., Dabrowska, K., Sloderbach, A., Skrzypczak, L., and Budzianowski, J. [Effect of flavonoid fractions of Solidago virgaurea L on diuresis and levels of electrolytes]. Acta Pol.Pharm 1991;48(5-6):35-37.
  4. Chodera, A., Dabrowska, K., Bobkiewicz-Kozlowska, T., Tkaczyk, J., Skrzypczak, L., and Budzianowski, J. [Effect of leiocarposide on experimental urinary calculi in rats]. Acta Pol.Pharm 1988;45(2):181-186.
  5. Chodera, A., Dabrowska, K., Skrzypczak, L., and Budzianowski, J. [Further studies on the diuretic effect of leiocarposide]. Acta Pol.Pharm 1986;43(5):499-503.
  6. Chodera, A., Dabrowska, K., Senczuk, M., Wasik-Olejnik, A., Skrzypczak, L., Budzianowski, J., and Ellnain-Wojtaszek, M. [Diuretic effect of the glycoside from a plant of the Solidago L. genus]. Acta Pol.Pharm 1985;42(2):199-204.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Goldenrod and Elbasvir, Grazoprevir Together: Common Questions

Is it safe to take Goldenrod with Elbasvir, Grazoprevir?
We do not list a known interaction between Goldenrod and Elbasvir, Grazoprevir. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Goldenrod and Elbasvir, Grazoprevir have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Goldenrod and Elbasvir, Grazoprevir combination checked?
Interactions in our licensed database are recorded against drug classes. Elbasvir, Grazoprevir is filed under 4 classifications, and Goldenrod has documented interactions with 1 drug class — none of Elbasvir, Grazoprevir's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Goldenrod interact with any other medications?
Yes. Goldenrod has 75 documented drug interactions in our database — Elbasvir, Grazoprevir is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Elbasvir, Grazoprevir interact with any supplements?
Yes. Elbasvir, Grazoprevir has documented interactions with 140 supplements in our database — Goldenrod is not one of them. The Elbasvir, Grazoprevir interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Goldenrod monograph Uses, safety profile, and every drug interaction in one place Elbasvir and Grazoprevir drug information The full plain-English guide to this medication Elbasvir, Grazoprevir supplement interactions Every supplement checked against Elbasvir, Grazoprevir, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 6 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Elbasvir, Grazoprevir and Goldenrod?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.