Drug & supplement interaction

Humann Superbeets Heart Chews + Treprostinil

Minor Interaction
Medically reviewed by · Updated November 2023
The bottom line Minor

Humann Superbeets Heart Chews has a minor interaction with Treprostinil. Each serving of HumanN SuperBeets includes 500mg of beetroot powder (2 chews).

Read the full interaction report
SeverityMinor
LikelihoodPossible
EvidenceA
What do Severity, Likelihood & Evidence mean?
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Interaction report

Humann Superbeets Heart Chews and Treprostinil

Here is the interaction we found between these two, with the evidence behind it.

Minor

Antihypertensive Drugs

Why this applies to Treprostinil

Treprostinil falls under Antihypertensive Drugs — the group Humann Superbeets Heart Chews interacts with.

Each serving of HumanN SuperBeets includes 500mg of beetroot powder (2 chews). Beetroot is rich in nitrates, which have the potential to widen blood vessels (vasodilation) and, in turn, possibly lower blood pressure. While there is a theoretical concern about the nitrate content in beets causing a blood pressure drop, research consistently indicates that any impact is generally minor and short-lived. However, it's crucial to be aware that blood pressure medications alone can cause dizziness and lightheadedness. Combining them with beet supplements might heighten the risk of experiencing these side effects due to the temporary vasodilation caused by the nitrates in beet.
Severity Minor Likelihood Possible Evidence A

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the thing to keep in mind: Treprostinil (Orenitram) is itself a powerful vasodilator. It works by relaxing and widening blood vessels in the lungs and body, which is why headache, flushing, jaw pain, diarrhea, and low blood pressure with dizziness are such common side effects. The beetroot nitrates in SuperBeets gently widen blood vessels too, so stacking the two could nudge those blood-pressure-lowering effects a little further.

The good news is that the beet effect is usually small and short-lived, so this is rated a minor interaction. Still, if you already feel lightheaded, flushed, or dizzy on your dose, adding the chews might make those moments more noticeable. I wouldn't start or stop anything on your own. Just run it by your doctor or pharmacist first, since pulmonary hypertension treatment is carefully balanced.

Contact Dr. Brian directly if you have additional questions on this interaction

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Humann Superbeets Heart Chews Also Interacts With Other Medications

Humann Superbeets Heart Chews has 893 minor known drug interactions in our database — the Treprostinil one above is one of them. If you take anything else, check it against the full list below.

Minor 893 No known interaction 1,937 (incl. Treprostinil)
Taking anything else?

Check Another of Your Medications Against Humann Superbeets Heart Chews

Covers the 2,830 medications we’ve checked against Humann Superbeets Heart Chews. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Treprostinil

This page covers Humann Superbeets Heart Chews only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Treprostinil page lists 291 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Danshen (major) and Piracetam (major).

By severity: 6 major · 258 moderate · 27 minor.

Open the Treprostinil interaction page

How much people look this up

Where Humann Superbeets Heart Chews and Treprostinil Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Humann Superbeets Heart Chews
Steady interest

#1,022 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Treprostinil
Steady interest

#1,613 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Humann Superbeets Heart Chews

What is Humann Superbeets Heart Chews?

Humann Superbeets Heart Chews
  • Heart and cardiovascular support
  • Healthy blood pressure support
  • Nitric oxide and blood flow support
  • Antioxidant support
  • Energy and circulation

SuperBeets Heart Chews are a beetroot- and grape-seed-based supplement marketed to support healthy blood flow, blood pressure, and nitric oxide production. Some research on dietary nitrate from beets and on grape seed extract suggests modest cardiovascular benefits, but evidence for this specific product is limited. It is generally well tolerated, but talk with your pharmacist or doctor before using it, especially if you have heart problems or take blood pressure medicine.

Read the full Humann Superbeets Heart Chews monograph & all interactions
Medication

About Treprostinil

What Is Treprostinil Used For?

Treprostinil treats pulmonary arterial hypertension (PAH; WHO Group 1) — high blood pressure in the arteries of the lungs. Depending on the product and route, it is used to improve exercise ability, delay disease progression, or reduce symptoms tied to physical activity. Remodulin and treprostinil injection products are also indicated for patients who need to transition away from another PAH medicine called epoprostenol.

Tyvaso, Tyvaso DPI, and Yutrepia (inhaled forms) are additionally approved to treat pulmonary hypertension associated with interstitial lung disease (PH-ILD; WHO Group 3) — lung-pressure problems caused by scarring or inflammation in the lung tissue itself. Orenitram (extended-release oral tablet) is specifically indicated to delay disease progression and improve exercise capacity in PAH.

See full Treprostinil drug information
Keep checking

Other Drugs & Humann Superbeets Heart Chews

Browse every other medication we’ve checked against Humann Superbeets Heart Chews — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
893Minor
1,936No known interaction
893 Minor 1,936 No interaction
Minor

893 interactions

Showing 60 of 893 minor interactions — see all 893 on the Humann Superbeets Heart Chews page.

No interaction 1,936 drugs checked — show the list

We also checked Humann Superbeets Heart Chews against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 1,936 medications checked with no known interaction — see the full Humann Superbeets Heart Chews list.

See the full Humann Superbeets Heart Chews interactions page
See every supplement checked against Treprostinil, ranked by severity
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Humann Superbeets Heart Chews monograph › Uses, safety, and every drug interaction in one place Treprostinil supplement interactions › Every supplement checked against Treprostinil, ranked by severity Treprostinil drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Humann Superbeets Heart Chews and Treprostinil Together: Common Questions

Can you take Humann Superbeets Heart Chews with Treprostinil?
There is only a minor interaction, which is usually not serious. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Humann Superbeets Heart Chews and Treprostinil interaction?
We rate it Minor. This interaction is generally not clinically significant, but it remains worth noting and discussing with your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Treprostinil and Humann Superbeets Heart Chews?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.