Drug & supplement interaction

Indigo Pulchra + Dofetilide

Dofetilide brand name: Tikosyn.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Indigo Pulchra and Dofetilide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Indigo Pulchra and Dofetilide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Dofetilide and Indigo Pulchra in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Indigo Pulchra safety at a glance

Indigo Pulchra overall Not established We cannot verify what this product is, so its safety is unknown.
Pregnancy Avoid With no safety data, avoid use during pregnancy.
Breastfeeding Avoid With no safety data, avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Dofetilide and Indigo Pulchra? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Dofetilide

Interactions in our licensed database are recorded against drug classes, not just single drug names. Dofetilide is filed under 3 classifications — qt interval-prolonging drugs, cytochrome p450 3a4 (cyp3a4) substrates, oral drugs. Indigo Pulchra has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Dofetilide’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Indigo Pulchra Does Interact With Other Medications

Indigo Pulchra has 86 moderate known drug interactions in our database — Dofetilide isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Dofetilide)
Taking anything else?

Check Another of Your Medications Against Indigo Pulchra

Covers the 2,830 medications we’ve checked against Indigo Pulchra. Pick one to open its full report.

What to actually watch for

What Dofetilide’s Own FDA Label Lists

This is not an interaction — none of it involves Indigo Pulchra. These are the most notable effects listed in the ADVERSE REACTIONS section of Dofetilide’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • An irregular heartbeat Worth acting on mentioned in 14.5% of FDA reports for Dofetilide
  • A stroke or mini-stroke Worth acting on
  • A slow heartbeat Worth acting on
  • Heart failure Worth acting on
  • Fainting Worth acting on
  • Shortness of breath Worth acting on mentioned in 5.9% of FDA reports for Dofetilide
  • Chest pain Worth acting on
  • Raised blood pressure Worth acting on
  • A severe allergic reaction Worth acting on
  • Liver problems Worth acting on

Showing the 10 most notable of 28 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Dofetilide. Read the label on DailyMed › Where a percentage is shown, it is the share of 10,450 voluntary FDA FAERS reports for Dofetilide that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Indigo Pulchra’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Indigo Pulchra side to compare — that is a limit of the record, not a statement that Indigo Pulchra has no side effects.

From our Q&A

Questions About Indigo Pulchra or Dofetilide

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Indigo Pulchra or Dofetilide, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Dofetilide

This page covers Indigo Pulchra only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Dofetilide page lists 146 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 8 major · 98 moderate · 40 minor.

From our pharmacist’s overview on the Dofetilide page

“Dofetilide (Tikosyn) controls abnormal heart rhythms, and it is dosed so precisely that most people start it in the hospital under ECG monitoring. Supplements deserve matching care.”

Reviewed by 2 · Jul 18, 2026

Open the Dofetilide interaction page

One more smart check

Taking Indigo Pulchra as Part of a Dietary Supplement Product? Check It for Interactions

We hold 9 real supplement products containing Indigo Pulchra, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Indigo Pulchra. Even though Indigo Pulchra itself has no known interaction with Dofetilide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Indigo Pulchra and Dofetilide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Indigo Pulchra
Top half

#717 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Dofetilide
Top 25%

#620 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Indigo Pulchra reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Indigo Pulchra and Dofetilide records this page draws on were last updated June 20, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Indigo Pulchra

What is Indigo Pulchra?

Indigo Pulchra is not a plant or supplement that we can find in any reliable scientific or herbal reference. Because we cannot confirm what it is, what it contains, or whether it is safe, we cannot responsibly describe its uses or dosing. If you have a product with this name, talk to a pharmacist before using it.

An interaction check asks whether these two react with each other — it does not ask whether Indigo Pulchra is a good idea for someone in your situation. Here is what our Indigo Pulchra record says about it on its own.

Indigo Pulchra: dosing

There is no established or recommended dose for Indigo Pulchra because it is not a recognized supplement. We cannot suggest any amount as safe.

From our Indigo Pulchra monograph — the full record covers uses, side effects and every documented interaction.

Read the full Indigo Pulchra monograph & all interactions
Medication

About Dofetilide

What Is Dofetilide Used For?

Brand name: Tikosyn

Dofetilide capsules are used in two main ways for people with atrial fibrillation (AF) or atrial flutter (AFl) — abnormal, often rapid heart rhythms. First, they can help convert these abnormal rhythms back to a normal heart rhythm. Second, once a normal rhythm has been restored, dofetilide can help maintain it and delay the time before the abnormal rhythm comes back.

Because dofetilide can cause dangerous heart rhythm problems of its own, it is reserved for patients whose atrial fibrillation or atrial flutter causes significant symptoms. It has not been shown to be effective for paroxysmal atrial fibrillation (short, self-terminating episodes). The brand Tikosyn carries the same two approved uses.

Most-Reported Side Effects for Dofetilide

From FAERS, the FDA’s public side-effect reporting system (10,450 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Atrial fibrillation 1,066 reports
Dyspnea 612 reports
Dizziness 559 reports
Fatigue 531 reports
Electrocardiogram qt prolonged 446 reports
See full Dofetilide drug information
Keep checking

Other Drugs & Indigo Pulchra

Browse every other medication we’ve checked against Indigo Pulchra — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Indigo Pulchra page.

No interaction 2,743 drugs checked — show the list

We also checked Indigo Pulchra against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Indigo Pulchra list.

See the full Indigo Pulchra interactions page
See every supplement checked against Dofetilide, ranked by severity
Evidence & sources

Indigo Pulchra References

The 2 references that drive our Indigo Pulchra monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Tanko Y, Abdelaziz MM, Adelaiye AB, Fatihu MY, Musa KY. Effects of Hydromethanolic leaves extract of Indigofera pulchra on blood glucose levels of normoglycemic and alloxan-induced diabetic Wistar rats. International Journal of Applied Research in Natural
  2. Tanko Y, Mabrouk MA, Adelaiye AB, Fatihu MY, and Musa KY. Anti-diabetic and some haematological effects of ethylacetate and n-butanol fractions of Indigofera pulchra extract on alloxan-induced diabetic Wistar rats. J Endocrinol Diabetes. 2011; 2(1): 1-7.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Indigo Pulchra and Dofetilide Together: Common Questions

Is it safe to take Indigo Pulchra with Dofetilide?
We do not list a known interaction between Indigo Pulchra and Dofetilide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Indigo Pulchra and Dofetilide combination checked?
Interactions in our licensed database are recorded against drug classes. Dofetilide is filed under 3 classifications, and Indigo Pulchra has documented interactions with 1 drug class — none of Dofetilide's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Indigo Pulchra interact with any other medications?
Yes. Indigo Pulchra has 86 documented drug interactions in our database — Dofetilide is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Dofetilide interact with any supplements?
Yes. Dofetilide has documented interactions with 146 supplements in our database — Indigo Pulchra is not one of them. The Dofetilide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Indigo Pulchra monograph Uses, safety profile, and every drug interaction in one place Dofetilide drug information The full plain-English guide to this medication Dofetilide supplement interactions Every supplement checked against Dofetilide, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Dofetilide and Indigo Pulchra?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.