Drug & supplement interaction

Kiwi + Lenacapavir

Lenacapavir brand name: Sunlenca.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 20, 2026

The bottom line No known interaction

We found no known interaction between Kiwi and Lenacapavir in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Kiwi and Lenacapavir

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Lenacapavir and Kiwi in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Kiwi safety at a glance

Kiwi overall Generally safe Kiwi is safe for most people when eaten as a normal food.

Pregnancy Likely Safe When used in food amounts. There is insufficient reliable information available about the safety of kiwi when used orally in medicinal amounts; avoid use. Read the full pregnancy detail

Breastfeeding Likely Safe When used in food amounts. There is insufficient reliable information available about the safety of kiwi when used orally in medicinal amounts; avoid use. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Lenacapavir and Kiwi? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

How we checked

Why No Interaction Is Listed for Lenacapavir

Interactions in our licensed database are recorded against drug classes, not just single drug names. Lenacapavir is filed under 2 classifications — cytochrome p450 3a4 (cyp3a4) substrates, oral drugs. Kiwi has documented interactions with 2 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate) and antihypertensive drugs (moderate) — and none of Lenacapavir’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Kiwi Does Interact With Other Medications

Kiwi has 289 moderate known drug interactions in our database — Lenacapavir isn’t one of them. If you take anything else, check it against the full list below.

Moderate 289 No known interaction 2,541 (incl. Lenacapavir)

Taking anything else?

Check Another of Your Medications Against Kiwi

Covers the 2,830 medications we’ve checked against Kiwi. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Kiwi and Lenacapavir May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

Nausea Additional detail
Kiwi
“Orally, kiwi fruit is generally well tolerated. Eating kiwi fruit or drinking the juice can lead to hypersensitivity reactions of the lips, mouth, tongue, and throat, including dysphagia, urticaria, dermatitis, angioedema, and vomiting immediately following ingestion in some patients (6,963,57465,57496,57491,57497,57635,57636,109591).”

Kiwi · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).
6 sources cited

6. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.

963. Diez-Gomez ML, Quirce S, Aragoneses E, Cuevas M. Asthma caused by Ficus benjamina latex: evidence of cross-reactivity with fig fruit and papain. Ann Allergy Asthma Immunol 1998;80:24-30.

57465. Ishida, T., Murai, K., Yasuda, T., Satou, T., Sejima, T., and Kitamura, K. [Oral allergy syndrome in patients with Japanese cedar pollinosis]. Nippon Jibiinkoka Gakkai Kaiho 2000;103(3):199-205. PubMed

57496. Lucas, J. S., Grimshaw, K. E., Collins, K., Warner, J. O., and Hourihane, J. O. Kiwi fruit is a significant allergen and is associated with differing patterns of reactivity in children and adults. Clin.Exp.Allergy 2004;34(7):1115-1121. PubMed

57491. Lucas, J. S., Lewis, S. A., and Hourihane, J. O. Kiwi fruit allergy: a review. Pediatr.Allergy Immunol. 2003;14(6):420-428. PubMed

57497. Hemmer, W., Focke, M., Gotz, M., and Jarisch, R. Sensitization to Ficus benjamina: relationship to natural rubber latex allergy and identification of foods implicated in the Ficus-fruit syndrome. Clin.Exp.Allergy 2004;34(8):1251-1258.
“Eating kiwi fruit or drinking the juice can lead to hypersensitivity reactions of the lips, mouth, tongue, and throat, including dysphagia, urticaria, dermatitis, angioedema, and vomiting immediately following ingestion in some patients (6,963,57465,57496,57491,57497,57635,57636,109591,109592). Other reported symptoms of kiwi allergy include nausea, diarrhea, and acute pancreatitis.”

Kiwi · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).
6 sources cited

6. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.

963. Diez-Gomez ML, Quirce S, Aragoneses E, Cuevas M. Asthma caused by Ficus benjamina latex: evidence of cross-reactivity with fig fruit and papain. Ann Allergy Asthma Immunol 1998;80:24-30.

57465. Ishida, T., Murai, K., Yasuda, T., Satou, T., Sejima, T., and Kitamura, K. [Oral allergy syndrome in patients with Japanese cedar pollinosis]. Nippon Jibiinkoka Gakkai Kaiho 2000;103(3):199-205. PubMed

57496. Lucas, J. S., Grimshaw, K. E., Collins, K., Warner, J. O., and Hourihane, J. O. Kiwi fruit is a significant allergen and is associated with differing patterns of reactivity in children and adults. Clin.Exp.Allergy 2004;34(7):1115-1121. PubMed

57491. Lucas, J. S., Lewis, S. A., and Hourihane, J. O. Kiwi fruit allergy: a review. Pediatr.Allergy Immunol. 2003;14(6):420-428. PubMed

57497. Hemmer, W., Focke, M., Gotz, M., and Jarisch, R. Sensitization to Ficus benjamina: relationship to natural rubber latex allergy and identification of foods implicated in the Ficus-fruit syndrome. Clin.Exp.Allergy 2004;34(8):1251-1258.
Lenacapavir

Listed in the ADVERSE REACTIONS section of the FDA label for Lenacapavir. Read the label on DailyMed ›

Reported for Kiwi but not commonly for Lenacapavir: a severe allergic reaction, pancreatitis, an allergic reaction and a skin rash.

Effects for Lenacapavir come from the ADVERSE REACTIONS section of its FDA label; effects for Kiwi come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Kiwi in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When used in food amounts. There is insufficient reliable information available about the safety of kiwi when used orally in medicinal amounts; avoid use.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Lenacapavir

This page covers Kiwi only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lenacapavir page lists 138 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 94 moderate · 41 minor.

From our pharmacist’s overview on the Lenacapavir page

“Lenacapavir (Sunlenca) treats HIV that has resisted other regimens, so keeping its blood level steady is not optional, and its list of 138 interacting supplements deserves genuine care. Nearly all of them, 121 ingredients, can shift how the body handles lenacapavir through the CYP3A4 enzyme, either pushing its level up along with side…”

Reviewed by 2 · Jul 18, 2026

Open the Lenacapavir interaction page

One more smart check

Taking Kiwi as Part of a Dietary Supplement Product? Check It for Interactions

We hold 361 real supplement products containing Kiwi, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Kiwi. Even though Kiwi itself has no known interaction with Lenacapavir, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Kiwi and Lenacapavir Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Kiwi

Top half

#407 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Lenacapavir

Top half

#1,332 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Kiwi reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Kiwi and Lenacapavir records this page draws on were last updated July 10, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Kiwi

What is Kiwi?

Constipation and digestive health
Vitamin C and antioxidant support
Sleep support
Immune support
Heart and cholesterol health

Kiwi is a nutritious fruit that is rich in vitamin C, fiber, and antioxidants, and it is generally safe to eat as a food. The strongest evidence is for helping with constipation and overall digestive regularity, while other uses like better sleep or immune support are far less proven. People with a known kiwi or latex allergy should avoid it.

Actinidia deliciosa · Actinidiaceae · Fruit (and seeds) · Fresh fruit, dried fruit, juice, extracts, capsules, powders

An interaction check asks whether these two react with each other — it does not ask whether Kiwi is a good idea for someone in your situation. Here is what our Kiwi record says about it on its own.

Kiwi: dosing

There is no official or standardized dose of kiwi for any health condition. In studies on digestion and sleep, people often ate about one to two kiwifruit per day, but this is not a formal medical recommendation.For kiwi supplements, juices, or powders, follow the directions on the product label, since the amount of active ingredients varies widely between products. Simply enjoying kiwi as a fruit is a safe and easy way to get its nutrients.

From our Kiwi monograph — the full record covers uses, side effects and every documented interaction.

Read the full Kiwi monograph & all interactions

Medication

About Lenacapavir Oral

What Is Lenacapavir Oral Used For?

Brand name: Sunlenca

Sunlenca tablets are used in two situations: to treat HIV-1 infection in adults whose virus has become resistant to multiple antiretroviral drugs and whose current regimen is failing — always in combination with other antiretrovirals — and as a short oral loading dose to start the BIXLENVO complete HIV-1 treatment regimen in adults who are already virologically suppressed (virus undetectable) and switching from a stable antiretroviral regimen.

Yeztugo tablets are used as part of HIV-1 pre-exposure prophylaxis (PrEP) — helping HIV-negative people reduce their risk of getting HIV-1. The oral tablet form is used during initiation of Yeztugo, and also as a temporary oral bridge if a scheduled injection must be delayed more than two weeks.

Most-Reported Side Effects for Lenacapavir

From FAERS, the FDA’s public side-effect reporting system (462 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Injection site discharge 141 reports

Injection site pain 137 reports

Injection site nodule 111 reports

Injection site erythema 40 reports

Injection site mass 36 reports

See full Lenacapavir Oral drug information

Keep checking

Other Drugs & Kiwi

Browse every other medication we’ve checked against Kiwi — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

289Moderate

0Minor

2,540No known interaction

289 Moderate 2,540 No interaction

Moderate

289 interactions

Showing 60 of 289 moderate interactions — see all 289 on the Kiwi page.

No interaction 2,540 drugs checked — show the list

We also checked Kiwi against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,540 medications checked with no known interaction — see the full Kiwi list.

See the full Kiwi interactions page

See every supplement checked against Lenacapavir, ranked by severity

Evidence & sources

Kiwi References

The 32 references that drive our Kiwi monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
Diez-Gomez ML, Quirce S, Aragoneses E, Cuevas M. Asthma caused by Ficus benjamina latex: evidence of cross-reactivity with fig fruit and papain. Ann Allergy Asthma Immunol 1998;80:24-30.
Forastiere F, Pistelli R, Sestini P, et al. Consumption of fresh fruit rich in vitamin C and wheezing symptoms in children. Thorax 2000;55:283-8. DOI
Carey IM, Strachan DP, Cook DG. Effects of changes in fresh fruit consumption on ventilatory function in healthy British adults. Am J Respir Crit Care Med 1998;158:728-33. PubMed
Schwartz J, Weiss ST. Relationship between dietary vitamin C intake and pulmonary function in the First National Health and Nutrition Examination Survey (NHANES I). Am J Clin Nutr 1994;59:110-4. PubMed
Butland BK, Fehily AM, Elwood PC. Diet, lung function, and lung function decline in a cohort of 2512 middle aged men. Thorax 2000;55:102-8. PubMed
Troisi RJ, Willett WC, Weiss ST, et al. A prospective study of diet and adult-onset asthma. Am J Respir Crit Care Med 1995;151:1401-8. PubMed
Blanco C, Diaz-Perales A, Collada C, et al. Class I chitinases as potential panallergens involved in the latex-fruit syndrome. J Allergy Clin Immunol 1999;103(3 Pt 1):507-13. PubMed
Diaz-Perales A, Collada C, Blanco C, et al. Cross-reactions in the latex-fruit syndrome: A relevant role of chitinases but not of complex asparagine-linked glycans. J Allergy Clin Immunol 1999;104:681-7. PubMed
Rance, F. and Dutau, G. Labial food challenge in children with food allergy. Pediatr Allergy Immunol. 1997;8(1):41-44. PubMed
Kim, K. T. and Hussain, H. Prevalence of food allergy in 137 latex-allergic patients. Allergy Asthma Proc 1999;20(2):95-97. PubMed
Ishida, T., Murai, K., Yasuda, T., Satou, T., Sejima, T., and Kitamura, K. [Oral allergy syndrome in patients with Japanese cedar pollinosis]. Nippon Jibiinkoka Gakkai Kaiho 2000;103(3):199-205. PubMed
Lucas, J. S., Lewis, S. A., and Hourihane, J. O. Kiwi fruit allergy: a review. Pediatr.Allergy Immunol. 2003;14(6):420-428. PubMed
Eriksson, N. E., Moller, C., Werner, S., Magnusson, J., Bengtsson, U., and Zolubas, M. Self-reported food hypersensitivity in Sweden, Denmark, Estonia, Lithuania, and Russia. J Investig.Allergol.Clin Immunol. 2004;14(1):70-79.
Lucas, J. S., Grimshaw, K. E., Collins, K., Warner, J. O., and Hourihane, J. O. Kiwi fruit is a significant allergen and is associated with differing patterns of reactivity in children and adults. Clin.Exp.Allergy 2004;34(7):1115-1121. PubMed
Hemmer, W., Focke, M., Gotz, M., and Jarisch, R. Sensitization to Ficus benjamina: relationship to natural rubber latex allergy and identification of foods implicated in the Ficus-fruit syndrome. Clin.Exp.Allergy 2004;34(8):1251-1258.
Duttaroy, A. K. and Jorgensen, A. Effects of kiwi fruit consumption on platelet aggregation and plasma lipids in healthy human volunteers. Platelets. 2004;15(5):287-292. PubMed
Chan, A. O., Leung, G., Tong, T., and Wong, N. Y. Increasing dietary fiber intake in terms of kiwifruit improves constipation in Chinese patients. World J Gastroenterol. 9-21-2007;13(35):4771-4775. PubMed
Chang, C. C., Lin, Y. T., Lu, Y. T., Liu, Y. S., and Liu, J. F. Kiwifruit improves bowel function in patients with irritable bowel syndrome with constipation. Asia Pac.J Clin.Nutr. 2010;19(4):451-457.
Brevik, A., Gaivao, I., Medin, T., Jorgenesen, A., Piasek, A., Elilasson, J., Karlsen, A., Blomhoff, R., Veggan, T., Duttaroy, A. K., and Collins, A. R. Supplementation of a western diet with golden kiwifruits (Actinidia chinensis var.'Hort 16A':) effect
Veraldi, S. and Schianchi-Veraldi, R. Contact urticaria from kiwi fruit. Contact Dermatitis 1990;22(4):244. PubMed
Garcia, B. E., de la Cuesta, C. G., Santos, F., Feliu, X., and Cordoba, H. A rare case of food allergy: monosensitivity to kiwi (Actinidia chinensis). Allergol.Immunopathol.(Madr.) 1989;17(4):217-218.
Falliers, C. J. Anaphylaxis to Kiwi fruit and related "exoti"" items. J.Asthma 1983;20(3):193-196.
Shimizu, T. and Morikawa, A. Anaphylaxis to kiwi fruit in a 12-year-old boy. J.Asthma 1995;32(2):159-160. PubMed
Novembre, E., Bernardini, R., Bertini, G., Massai, G., and Vierucci, A. Skin-prick-test-induced anaphylaxis. Allergy 1995;50(6):511-513. PubMed
Castillo, R., Delgado, J., Quiralte, J., Blanco, C., and Carrillo, T. Food hypersensitivity among adult patients: epidemiological and clinical aspects. Allergol.Immunopathol.(Madr.) 1996;24(3):93-97.
Rademaker, M. Allergic contact dermatitis from kiwi fruit vine (actinidia chinensis). Contact Dermatitis 1996;34(3):221-222. PubMed
Gastaminza, G., Bernaola, G., and Camino, M. E. Acute pancreatitis caused by allergy to kiwi fruit. Allergy 1998;53(11):1104-1105. PubMed
Svendsen, M., Klemsdal, T. O., Heggen, E., Holme, I., Pedersen, T. R., Seljeflot, I., Blomhoff, R., and Tonstad, S. Effect of Dietary Intake of Kiwi Fruit on 24-Hour Ambulatory Blood Pressure (Abstract 16175). Circulation 2011;
Eady SL, Wallace AJ, Hedderley DI, Bentley-Hewitt KL, Butts CA. The effects on immune function and digestive health of consuming the skin and flesh of Zespri SunGold Kiwifruit (Actinidia Chinensis var. Chinensis 'Zesy002') in healthy and IBS-constipated i
Gabrielli S, Clarke AE, Morris J, et al. Fruit-induced anaphylaxis: clinical presentation and management. J Allergy Clin Immunol Pract 2021;9(7):2825-30. PubMed
Ukleja-Sokolowska N, Zacniewski R, Lis K, Zbikowska-Gotz M, Kuzminski A, Bartuzi Z. Exercise induced anaphylaxis in kiwi allergic patient: case report. Allergy Asthma Clin Immunol 2021;17(1):91. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Kiwi and Lenacapavir Together: Common Questions

Is it safe to take Kiwi with Lenacapavir?

We do not list a known interaction between Kiwi and Lenacapavir. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Do Kiwi and Lenacapavir have any of the same side effects?

Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.

How was the Kiwi and Lenacapavir combination checked?

Interactions in our licensed database are recorded against drug classes. Lenacapavir is filed under 2 classifications, and Kiwi has documented interactions with 2 drug classes — none of Lenacapavir's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.

Does Kiwi interact with any other medications?

Yes. Kiwi has 289 documented drug interactions in our database — Lenacapavir is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Does Lenacapavir interact with any supplements?

Yes. Lenacapavir has documented interactions with 138 supplements in our database — Kiwi is not one of them. The Lenacapavir interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Kiwi monograph Uses, safety profile, and every drug interaction in one place Lenacapavir Oral drug information The full plain-English guide to this medication Lenacapavir supplement interactions Every supplement checked against Lenacapavir, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 32 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Lenacapavir and Kiwi?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.