Drug & supplement interaction

Lemongrass + Metformin

Metformin brand names: Glucophage, Metformin.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Lemongrass and Metformin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Lemongrass and Metformin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Metformin and Lemongrass in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lemongrass safety at a glance

Lemongrass overall Use caution Likely safe in food amounts, but concentrated extracts and the essential oil have less safety data.
Pregnancy Likely Unsafe When used orally. Lemongrass seems to have uterine and menstrual flow stimulating effects; avoid using. Read the full pregnancy detail
Breastfeeding Use caution Not enough reliable data; avoid medicinal amounts and stick to occasional food use.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Metformin and Lemongrass? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Metformin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Metformin is filed under 5 classifications — including organic cation transporter 2 (oct2) substrates, antidiabetes drugs, oral drugs. Lemongrass has documented interactions with 3 drug classes — the most serious being cytochrome p450 3a4 (cyp3a4) substrates (moderate), glucuronidated drugs (moderate) and pentobarbital (nembutal) (moderate) — and none of Metformin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Lemongrass Does Interact With Other Medications

Lemongrass has 708 moderate known drug interactions in our database — Metformin isn’t one of them. If you take anything else, check it against the full list below.

Moderate 708 No known interaction 2,122 (incl. Metformin)
Taking anything else?

Check Another of Your Medications Against Lemongrass

Covers the 2,830 medications we’ve checked against Lemongrass. Pick one to open its full report.

What to actually watch for

What Metformin’s Own FDA Label Lists

This is not an interaction — none of it involves Lemongrass. These are the most notable effects listed in the ADVERSE REACTIONS section of Metformin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 5 of them are worth acting on rather than waiting out — marked below.

  • Low blood sugar Worth acting on
  • High blood sugar Worth acting on
  • Chest pain Worth acting on
  • Shortness of breath Worth acting on
  • Liver problems Worth acting on
  • A change in taste
  • Chills
  • Flushing
  • Bloating or gas
  • Sweating

Showing the 10 most notable of 19 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Metformin. Read the label on DailyMed › Lemongrass’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Lemongrass side to compare — that is a limit of the record, not a statement that Lemongrass has no side effects.

Special populations

Lemongrass in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally. Lemongrass seems to have uterine and menstrual flow stimulating effects; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Metformin Is Prescribed For, and What Lemongrass Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Metformin is a prescription medicine with approved uses on its FDA label. Lemongrass is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Metformin is prescribed for: Metformin is used to improve blood sugar (glucose) control in people with type 2 diabetes mellitus. It is always used together with diet and exercise, not instead of them. Metformin hydrochloride tablets and oral solution are approved for adults and children 10 years and older. Metformin hydrochloride extended-release tablets — including brands such as Fortamet, Glumetza, and Metformin Hydrochloride Extended Release — are approved for adults only.

Lemongrass has been studied for:

  • Diabetes studied, not established Lemongrass has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Lemongrass for diabetes

    Although there has been interest in using oral lemongrass for diabetes, there is insufficient reliable information about the clinical effects of lemongrass for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Metformin on your own; if you are taking Lemongrass for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Lemongrass or Metformin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Lemongrass or Metformin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Metformin

This page covers Lemongrass only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Metformin page lists 258 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Siberian Cocklebur (major), Acai (moderate), African Wild Potato (moderate) and Agaricus Mushroom (moderate).

By severity: 2 major · 217 moderate · 39 minor.

From our pharmacist’s overview on the Metformin page

“Siberian cocklebur is the ingredient I most want anyone taking metformin (Glucophage) to know about. It has caused severe low blood sugar in people, documented in humans, and it should not be combined with any glucose-lowering medication.”

Reviewed by 2 · Jul 18, 2026

Open the Metformin interaction page

One more smart check

Taking Lemongrass as Part of a Dietary Supplement Product? Check It for Interactions

We hold 417 real supplement products containing Lemongrass, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Lemongrass. Even though Lemongrass itself has no known interaction with Metformin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Lemongrass and Metformin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lemongrass
Top 25%

#332 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Metformin
Top 1%

#29 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lemongrass reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Lemongrass and Metformin records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Lemongrass

What is Lemongrass?

Lemongrass
  • Digestive upset
  • Anxiety and stress
  • Antimicrobial/antifungal
  • Insect repellent
  • Flavoring in food and drinks

Lemongrass is a fragrant tropical grass widely used as a cooking herb, a tea, and an aromatherapy oil. It is generally considered safe in the small amounts used in food, but most of its claimed health benefits come from laboratory or animal studies rather than strong human research. Talk with your pharmacist or doctor before using concentrated supplements or the essential oil, especially if you are pregnant or breastfeeding.

Cymbopogon citratus · Poaceae · Leaves, stalks, and essential oil · Tea, fresh or dried herb, capsules, essential oil, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Lemongrass is a good idea for someone in your situation. Here is what our Lemongrass record says about it on its own.

Lemongrass: dosing

There is no official standardized dose for lemongrass. The amount used depends on the form, such as tea, capsule, or essential oil.For tea, people commonly steep a small amount of dried or fresh leaves in hot water. For supplements, follow the directions on the product label, since strength varies from brand to brand.

From our Lemongrass monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lemongrass monograph & all interactions
Medication

About Metformin

What Is Metformin Used For?

Brand names: Glucophage, Metformin

Metformin is used to improve blood sugar (glucose) control in people with type 2 diabetes mellitus. It is always used together with diet and exercise, not instead of them.

Metformin hydrochloride tablets and oral solution are approved for adults and children 10 years and older. Metformin hydrochloride extended-release tablets — including brands such as Fortamet, Glumetza, and Metformin Hydrochloride Extended Release — are approved for adults only.

See full Metformin drug information
Keep checking

Other Drugs & Lemongrass

Browse every other medication we’ve checked against Lemongrass — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
708Moderate
0Minor
2,121No known interaction
708 Moderate 2,121 No interaction
Moderate

708 interactions

Showing 60 of 708 moderate interactions — see all 708 on the Lemongrass page.

No interaction 2,121 drugs checked — show the list

We also checked Lemongrass against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,121 medications checked with no known interaction — see the full Lemongrass list.

See the full Lemongrass interactions page
See every supplement checked against Metformin, ranked by severity
Evidence & sources

Lemongrass References

The 2 references that drive our Lemongrass monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Li CC, Yu HF, Chang CH, Liu YT, Yao HT. Effects of lemongrass oil and citral on hepatic drug-metabolizing enzymes, oxidative stress, and acetaminophen toxicity in rats. J Food Drug Anal 2018;26(1):432-8. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lemongrass and Metformin Together: Common Questions

Is it safe to take Lemongrass with Metformin?
We do not list a known interaction between Lemongrass and Metformin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Lemongrass and Metformin used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Lemongrass in each. That is a conversation for your prescriber, especially if Metformin is being adjusted to a target.
How was the Lemongrass and Metformin combination checked?
Interactions in our licensed database are recorded against drug classes. Metformin is filed under 5 classifications, and Lemongrass has documented interactions with 3 drug classes — none of Metformin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Lemongrass interact with any other medications?
Yes. Lemongrass has 708 documented drug interactions in our database — Metformin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Metformin interact with any supplements?
Yes. Metformin has documented interactions with 258 supplements in our database — Lemongrass is not one of them. The Metformin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Lemongrass monograph Uses, safety profile, and every drug interaction in one place Metformin drug information The full plain-English guide to this medication Metformin supplement interactions Every supplement checked against Metformin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Metformin and Lemongrass?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.