Drug & supplement interaction

Limosilactobacillus Fermentum + tislelizumab-jsgr

tislelizumab-jsgr brand name: Tevimbra.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Limosilactobacillus Fermentum and tislelizumab-jsgr in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Limosilactobacillus Fermentum and tislelizumab-jsgr

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between tislelizumab-jsgr and Limosilactobacillus Fermentum in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Limosilactobacillus Fermentum safety at a glance

Limosilactobacillu... overall Use caution Generally well tolerated in healthy people, but evidence and quality vary by product and strain.
Pregnancy Use caution Some strains have been studied in pregnancy, but safety is not firmly established, so check with your doctor first.
Breastfeeding Possibly Safe When used orally and appropriately. Limosilactobacillus fermentum CECT5716 has been used with apparent safety when breastfeeding for up to 16 weeks. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining tislelizumab-jsgr and Limosilactobacillus Fermentum? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for tislelizumab-jsgr

Interactions in our licensed database are recorded against drug classes, not just single drug names. tislelizumab-jsgr is filed under 2 classifications — nephrotoxic drugs, hepatotoxic drugs. Limosilactobacillus Fermentum has documented interactions with 1 drug class — the most serious being antibiotic drugs (moderate) — and none of tislelizumab-jsgr’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Limosilactobacillus Fermentum Does Interact With Other Medications

Limosilactobacillus Fermentum has 182 moderate known drug interactions in our database — tislelizumab-jsgr isn’t one of them. If you take anything else, check it against the full list below.

Moderate 182 No known interaction 2,648 (incl. tislelizumab-jsgr)
Taking anything else?

Check Another of Your Medications Against Limosilactobacillus Fermentum

Covers the 2,830 medications we’ve checked against Limosilactobacillus Fermentum. Pick one to open its full report.

What to actually watch for

What Limosilactobacillus Fermentum Itself Has Been Linked To

This is not an interaction — nothing below involves tislelizumab-jsgr. It is the side-effect record for Limosilactobacillus Fermentum on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Limosilactobacillus Fermentum, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • A higher chance of infection Worth acting on Additional detail

    “Since Limosilactobacillus fermentum preparations contain live and active microorganisms, there is some concern that they might cause pathogenic infection in some patients. Some lactobacilli species have been isolated in cases of bacteremia, sepsis, splenic abscess, endocarditis, necrotizing fasciitis, pancreatic necrosis, and meningoencephalitis.”

    Limosilactobacillus Fermentum · Natural Medicines adverse-effect record, reported in sepsis.

    6 sources cited
    1. 107543. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
    2. 110917. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
    3. 110918. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
    4. 110920. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
    5. 110921. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
    6. 112565. Achuthanandan S, Dhaliwal A, Lu T, Sharma K. Brain abscess due to Lactobacillus fermentum in an uncontrolled diabetic. Cureus 2022;14(6):e26360. PubMed
  • Stomach upset Additional detail

    Recorded for Limosilactobacillus Fermentum in the same Natural Medicines adverse-effect record shown under A higher chance of infection above.

Everything above comes from the Natural Medicines adverse-effect record for Limosilactobacillus Fermentum — expand a row for the licensed statement it rests on. We haven’t matched tislelizumab-jsgr to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for tislelizumab-jsgr.

Special populations

Limosilactobacillus Fermentum in Pregnancy & Breastfeeding

Lactation Possibly Safe

When used orally and appropriately. Limosilactobacillus fermentum CECT5716 has been used with apparent safety when breastfeeding for up to 16 weeks.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With tislelizumab-jsgr

This page covers Limosilactobacillus Fermentum only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the tislelizumab-jsgr page lists 42 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Asarabacca (major), Beer (major), Siberian Cocklebur (major), Wine (major) and Aristolochia (moderate).

By severity: 4 major · 37 moderate · 1 minor.

From our pharmacist’s overview on the tislelizumab-jsgr page

“Alcohol, even ordinary beer and wine, sits at the top of my concerns for anyone receiving tislelizumab-jsgr (Tevimbra), an immunotherapy for certain cancers of the esophagus and stomach. Drugs in this class can provoke immune attacks on the liver, and 38 of the 42 supplement ingredients on this page add liver stress of their own, so ne…”

Reviewed by 2 · Jul 18, 2026

Open the tislelizumab-jsgr interaction page

How much people look this up

Where Limosilactobacillus Fermentum and tislelizumab-jsgr Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Limosilactobacillus Fermentum
Top half

#489 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication tislelizumab-jsgr
Top half

#920 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Limosilactobacillus Fermentum reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Limosilactobacillus Fermentum and tislelizumab-jsgr records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Limosilactobacillus Fermentum

What is Limosilactobacillus Fermentum?

  • Digestive health
  • Immune support
  • Vaginal and urinary health
  • Cholesterol support
  • Oral health

Limosilactobacillus fermentum (formerly Lactobacillus fermentum) is a probiotic bacterium found in fermented foods and the human body, used to support gut, immune, and women's health. Early research is promising for some uses but most evidence is preliminary, and effects can differ by strain. It is generally well tolerated in healthy people, but talk to your pharmacist or doctor before starting, especially if your immune system is weak.

Limosilactobacillus fermentum · Lactobacillaceae · Whole live bacteria (probiotic strain) · Capsules, tablets, powders, fermented foods, and combination probiotic products

An interaction check asks whether these two react with each other — it does not ask whether Limosilactobacillus Fermentum is a good idea for someone in your situation. Here is what our Limosilactobacillus Fermentum record says about it on its own.

Limosilactobacillus Fermentum: dosing

There is no official standardized dose for Limosilactobacillus fermentum. Probiotic amounts are usually measured in colony-forming units (CFU), and the right amount depends on the strain and the product.The best approach is to follow the directions on the product label. Do not assume more is better.

From our Limosilactobacillus Fermentum monograph — the full record covers uses, side effects and every documented interaction.

Read the full Limosilactobacillus Fermentum monograph & all interactions
Medication

About tislelizumab-jsgr

Most-Reported Side Effects for tislelizumab-jsgr

From FAERS, the FDA’s public side-effect reporting system (177 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Disease progression 64 reports
Malignant neoplasm progression 22 reports
Anemia 21 reports
Lymphadenopathy 19 reports
Thrombocytopenia 19 reports
Keep checking

Other Drugs & Limosilactobacillus Fermentum

Browse every other medication we’ve checked against Limosilactobacillus Fermentum — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
182Moderate
0Minor
2,647No known interaction
182 Moderate 2,647 No interaction
Moderate

182 interactions

Showing 60 of 182 moderate interactions — see all 182 on the Limosilactobacillus Fermentum page.

No interaction 2,647 drugs checked — show the list

We also checked Limosilactobacillus Fermentum against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,647 medications checked with no known interaction — see the full Limosilactobacillus Fermentum list.

See the full Limosilactobacillus Fermentum interactions page
See every supplement checked against tislelizumab-jsgr, ranked by severity
Evidence & sources

Limosilactobacillus Fermentum References

The 12 references that drive our Limosilactobacillus Fermentum monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  3. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  4. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  5. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  6. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  7. Achuthanandan S, Dhaliwal A, Lu T, Sharma K. Brain abscess due to Lactobacillus fermentum in an uncontrolled diabetic. Cureus 2022;14(6):e26360. PubMed
  8. Pastor-Villaescusa B, Hurtado JA, Gil-Campos M, et al. Effects of Lactobacillus fermentum CECT5716 Lc40 on infant growth and health: a randomised clinical trial in nursing women. Benef Microbes 2020;11(3):235-244. PubMed
  9. Jiménez-Gutiérrez JM, Peláez-Luna M, Campos-Murguía A. A rare case of emphysematous gastritis caused by Lactobacillus fermentum in a patient with diabetes. Rev Esp Enferm Dig 2021;113(9):670-671. PubMed
  10. Greig JR, Eltringham IJ, Birthistle K. Primary peritonitis due to Lactobacillus fermentum. J Infect 1998;36(2):242-3. PubMed
  11. Woo PC, Lau SK, Lin AW, Curreem SO, Fung AM, Yuen KY. Surgical site abscess caused by Lactobacillus fermentum identified by 16S ribosomal RNA gene sequencing. Diagn Microbiol Infect Dis 2007;58(2):251-4. PubMed
  12. Gallemore GH, Mohon RT, Ferguson DA. Lactobacillus fermentum endocarditis involving a native mitral valve. J Tenn Med Assoc 1995;88(8):306-8.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Limosilactobacillus Fermentum and tislelizumab-jsgr Together: Common Questions

Is it safe to take Limosilactobacillus Fermentum with tislelizumab-jsgr?
We do not list a known interaction between Limosilactobacillus Fermentum and tislelizumab-jsgr. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Limosilactobacillus Fermentum and tislelizumab-jsgr combination checked?
Interactions in our licensed database are recorded against drug classes. tislelizumab-jsgr is filed under 2 classifications, and Limosilactobacillus Fermentum has documented interactions with 1 drug class — none of tislelizumab-jsgr's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Limosilactobacillus Fermentum interact with any other medications?
Yes. Limosilactobacillus Fermentum has 182 documented drug interactions in our database — tislelizumab-jsgr is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does tislelizumab-jsgr interact with any supplements?
Yes. tislelizumab-jsgr has documented interactions with 42 supplements in our database — Limosilactobacillus Fermentum is not one of them. The tislelizumab-jsgr interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Limosilactobacillus Fermentum monograph Uses, safety profile, and every drug interaction in one place tislelizumab-jsgr supplement interactions Every supplement checked against tislelizumab-jsgr, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 12 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.