Drug & supplement interaction

Mullein + Propranolol

Propranolol brand names: Inderal LA, Inderal, Angilol, Syprol, Inderal Injection, and others.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Mullein and Propranolol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Mullein and Propranolol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Propranolol and Mullein in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Mullein safety at a glance

Mullein overall Use caution Generally well tolerated for short-term use, but human safety data are limited.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid There is not enough data to consider it safe while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Propranolol and Mullein? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Propranolol

Interactions in our licensed database are recorded against drug classes, not just single drug names. Propranolol is filed under 9 classifications — including beta-blockers, cytochrome p450 2c19 (cyp2c19) substrates, antihypertensive drugs. Mullein has documented interactions with 1 drug class — the most serious being anticoagulant/antiplatelet drugs (minor) — and none of Propranolol’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Mullein Does Interact With Other Medications

Mullein has 122 minor known drug interactions in our database — Propranolol isn’t one of them. If you take anything else, check it against the full list below.

Minor 122 No known interaction 2,708 (incl. Propranolol)
Taking anything else?

Check Another of Your Medications Against Mullein

Covers the 2,830 medications we’ve checked against Mullein. Pick one to open its full report.

What to actually watch for

What Mullein Itself Has Been Linked To

This is not an interaction — nothing below involves Propranolol. It is the side-effect record for Mullein on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Mullein, this list is the first place to look.

  • A skin rash Additional detail

    “Two case reports have described dermatitis, with positive patch tests, after topical exposure to the whole plant, or by occupational inhalation of plant dust. In the case of topical exposure, the patient also had positive patch tests to other plants.”

    Mullein · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 92839. Castro AI, Carmona JB, Gonzales FG, Nestar OB. Occupational airborne dermatitis from gordolobo (Verbascum densiflorum). Contact Dermatitis 2006;55(5):301.
    2. 97316. Flores Echaiz C, Al Ali A, Cao AQ, Sasseville D. Simultaneous contact dermatitis caused by Asteraceae and Verbascum thapsus. Contact Dermatitis 2017;76(5):316-8.

Everything above comes from the Natural Medicines adverse-effect record for Mullein — expand a row for the licensed statement it rests on. We haven’t matched Propranolol to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Propranolol.

From our Q&A

Questions About Mullein or Propranolol

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Mullein or Propranolol, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Propranolol

This page covers Mullein only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Propranolol page lists 236 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Indian Snakeroot (major) and Tyramine (major).

By severity: 5 major · 194 moderate · 37 minor.

From our pharmacist’s overview on the Propranolol page

“Propranolol (Inderal) slows the heart and lowers blood pressure, which is exactly why its 236-ingredient interaction list deserves genuine care. Five entries rate major, and those are the ones to understand first.”

Reviewed by 2 · Jul 18, 2026

Open the Propranolol interaction page

One more smart check

Taking Mullein as Part of a Dietary Supplement Product? Check It for Interactions

We hold 780 real supplement products containing Mullein, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Mullein. Even though Mullein itself has no known interaction with Propranolol, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Mullein and Propranolol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Mullein
Top 25%

#184 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Propranolol
Top 1%

#11 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Mullein reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Mullein and Propranolol records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Mullein

What is Mullein?

Mullein
  • Cough and chest congestion
  • Sore throat
  • Bronchitis and respiratory irritation
  • Earache (traditional ear oil)
  • Mild inflammation

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality human studies are lacking, so its benefits are not well proven, but it is generally considered low-risk for short-term use in healthy adults. Talk to your pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have a medical condition.

Verbascum thapsus · Scrophulariaceae · Leaves and flowers (sometimes roots) · Tea (infusion), tincture, capsules, syrups, lozenges, and ear oil drops

An interaction check asks whether these two react with each other — it does not ask whether Mullein is a good idea for someone in your situation. Here is what our Mullein record says about it on its own.

Mullein: dosing

There is no official or standardized dose for mullein. The amount used varies widely between products and traditional recipes, such as teas, tinctures, capsules, and syrups.The safest approach is to follow the directions on the product label and not exceed the recommended amount. A well-made tea is typically prepared by steeping the dried leaves or flowers in hot water and straining well to remove the irritating plant hairs.

From our Mullein monograph — the full record covers uses, side effects and every documented interaction.

Read the full Mullein monograph & all interactions
Medication

About Propranolol (Cardiovascular)

What Is Propranolol (Cardiovascular) Used For?

Brand names: Inderal LA, Inderal, Angilol, Syprol, Inderal Injection, Half-Inderal LA, Bedranol SR, Half Beta Prograne, Beta Prograne, Lopranol LA, Slo-Pro, InnoPran XL

This intravenous (IV) form of propranolol is used in hospital or clinical settings to treat dangerous heart rhythm problems. It is generally reserved for life-threatening arrhythmias (abnormal heart rhythms) or those that occur during anesthesia.

Specific conditions it treats include fast heart rates coming from the upper chambers of the heart (supraventricular tachycardia), certain arrhythmias caused by digitalis toxicity, dangerous ventricular rhythms that haven't responded to other treatments, and fast heart rates caused by excess adrenaline-like substances during surgery.

See full Propranolol (Cardiovascular) drug information
Keep checking

Other Drugs & Mullein

Browse every other medication we’ve checked against Mullein — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
122Minor
2,707No known interaction
122 Minor 2,707 No interaction
Minor

122 interactions

Showing 60 of 122 minor interactions — see all 122 on the Mullein page.

No interaction 2,707 drugs checked — show the list

We also checked Mullein against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,707 medications checked with no known interaction — see the full Mullein list.

See the full Mullein interactions page
See every supplement checked against Propranolol, ranked by severity
Evidence & sources

Mullein References

The 2 references that drive our Mullein monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Castro AI, Carmona JB, Gonzales FG, Nestar OB. Occupational airborne dermatitis from gordolobo (Verbascum densiflorum). Contact Dermatitis 2006;55(5):301.
  2. Flores Echaiz C, Al Ali A, Cao AQ, Sasseville D. Simultaneous contact dermatitis caused by Asteraceae and Verbascum thapsus. Contact Dermatitis 2017;76(5):316-8.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Mullein and Propranolol Together: Common Questions

Is it safe to take Mullein with Propranolol?
We do not list a known interaction between Mullein and Propranolol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Mullein and Propranolol combination checked?
Interactions in our licensed database are recorded against drug classes. Propranolol is filed under 9 classifications, and Mullein has documented interactions with 1 drug class — none of Propranolol's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Mullein interact with any other medications?
Yes. Mullein has 122 documented drug interactions in our database — Propranolol is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Propranolol interact with any supplements?
Yes. Propranolol has documented interactions with 236 supplements in our database — Mullein is not one of them. The Propranolol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Mullein monograph Uses, safety profile, and every drug interaction in one place Propranolol (Cardiovascular) drug information The full plain-English guide to this medication Propranolol supplement interactions Every supplement checked against Propranolol, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Propranolol and Mullein?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.