Oregano - Doxycycline Hyclate Interaction

Interaction Details

Pharmacist Analysis

Oregano (and oregano oil) supplements are generally considered safe and there is no indication that there is an interaction between the drug highlighted in this interaction monograph and oregano.

However, as with all supplements, it is important to talk to your doctor before starting anything new, so you can be appropriately monitored.

In terms of drug interactions that have been reported with oregano, below are some examples.

Anticoagulant; Antiplatelet Drugs

Anticoagulants and antiplatelet drugs work by slowing down or preventing blood clotting. While they are essential medications for individuals with certain conditions, they come with an increased risk of bleeding.

Some studies have reported that oregano oil may also increase the risk of bleeding, as it contains compounds that have antithrombin activity and can inhibit platelet aggregation.

Therefore, taking oregano oil along with anticoagulants or antiplatelet drugs may increase the risk of bleeding, bruising, and other adverse effects.

Anti-Diabetic Drugs

Several studies suggest that oregano supplements may help lower blood glucose (i.e., sugar) levels. In vitro and animal research has shown that oregano extracts might stimulate glucose uptake and reduce blood glucose levels.

Therefore, based on the available evidence, combining oregano oil with antidiabetic drugs could potentially cause blood sugar levels to drop too low, leading to hypoglycemia.

However, it is important to note that studies reporting that oregano can reduce blood glucose levels have not reported it causing hypoglycemia.

References

• Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. PubMed
• Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. PubMed
• Antithrombin activity of some constituents from Origanum vulgare. PubMed
• Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. PubMed

Doxycycline Hyclate Overview

• Doxycycline is used to treat a variety of infections caused by certain types of bacteria. Doxycycline is also used to treat or prevent anthrax (a serious infection that may be spread on purpose as part of a bioterror attack) in people who may have been exposed to anthrax in the air and to treat plague and tuleramia (serious infections that may be spread on purpose as part of a bioterror attack). It is also used to prevent malaria. Doxycycline is also used along with other medications to treat acne and rosacea (a skin disease that causes redness, flushing, and pimples on the face). Doxycycline (Oracea) is used only to treat pimples and bumps caused by rosacea. Doxycycline is in a class of medications called tetracycline antibiotics. It works to treat infections by preventing the growth and spread of bacteria. It works to treat acne by killing the bacteria that infects pores and decreasing a certain natural oily substance that causes acne. It works to treat rosacea by decreasing the inflammation that causes this condition.

• Antibiotics such as doxycycline will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

Oregano - More Interactions

Oregano interacts with 205 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.