Drug & supplement interaction

Red Raspberry + Tirofiban

Tirofiban brand name: Aggrastat.

Moderate Interaction
The bottom line Moderate

Red Raspberry has a moderate interaction with Tirofiban. Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Red Raspberry and Tirofiban

Here is the interaction we found between these two, with the evidence behind it.

Moderate

ANTICOAGULANT/ANTIPLATELET DRUGS

Why this applies to Tirofiban

Tirofiban falls under ANTICOAGULANT/ANTIPLATELET DRUGS — the group Red Raspberry interacts with.

Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
In vitro research suggests that red raspberry leaf extract has antiplatelet activity and enhances the in vitro effects of the antiplatelet medication cangrelor. This interaction has not been reported in humans.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the gist for Tirofiban (Aggrastat). This is a strong IV blood thinner (an antiplatelet drug) given in the hospital during heart procedures, so it's already keeping your platelets from clumping. In lab dish studies, red raspberry leaf seemed to have its own mild antiplatelet action, meaning it might add to that blood-thinning effect and, in theory, raise the chance of bleeding or bruising.

The key word is theoretical. This has only been seen in test-tube research, never reported in actual people, so I wouldn't lose sleep over it. Still, since Tirofiban is a serious hospital medication, let your care team know about any raspberry leaf tea or supplements you take so they can keep an eye on you.

References
  1. Dudzinska D, Bednarska K, Boncler M, Luzak B, Watala C. The influence of Rubus idaeus and Rubus caesius leaf extracts on platelet aggregation in whole blood. Cross-talk of platelets and neutrophils. Platelets. 2016;27(5):433-9.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Red Raspberry Also Interacts With Other Medications

Red Raspberry has 134 moderate known drug interactions in our database — the Tirofiban one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Red Raspberry

Covers the 2,830 medications we’ve checked against Red Raspberry. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Tirofiban

This page covers Red Raspberry only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tirofiban page lists 202 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Danshen (major), Piracetam (major), Aconite (moderate), Allspice (moderate) and Aloe (moderate).

By severity: 2 major · 183 moderate · 17 minor.

From our pharmacist’s overview on the Tirofiban page

“Danshen, an herb taken for heart and circulation problems, tops my concerns for anyone receiving tirofiban (Aggrastat). Tirofiban is an intravenous antiplatelet drug used during heart attacks and cardiac procedures to keep platelets from clumping, so a supplement that also thins the blood compounds the one danger that matters here, ser…”

Reviewed by 2 · Jul 18, 2026

Open the Tirofiban interaction page

One more smart check

Taking Red Raspberry as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1,303 real supplement products containing Red Raspberry, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Red Raspberry. Your product may carry other ingredients that interact with Tirofiban too, on top of Red Raspberry — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Red Raspberry and Tirofiban Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Red Raspberry
Top 25%

#170 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tirofiban
Steady interest

#2,622 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Red Raspberry

What is Red Raspberry?

  • Pregnancy and labor support
  • Menstrual cramps
  • Digestive upset and diarrhea
  • Sore throat and mouth rinse
  • Antioxidant support

Red raspberry leaf is a traditional herbal remedy most often used as a tea in late pregnancy and for menstrual discomfort, but solid scientific evidence for these uses is limited. It is generally considered well tolerated by most adults, but pregnant people should talk with their doctor or midwife before using it.

Read the full Red Raspberry monograph & all interactions
Medication

About Tirofiban

What Is Tirofiban Used For?

Brand name: Aggrastat

Tirofiban hydrochloride injection — available as Aggrastat and under the generic names Tirofiban and Tirofiban Hydrochloride — is used intravenously in people with non-ST elevation acute coronary syndrome (NSTE-ACS), a type of unstable heart condition where blood flow to the heart is dangerously reduced.

The goal is to lower the combined risk of death, heart attack (myocardial infarction), or persistent ischemia (insufficient blood flow to the heart) that may require a repeat cardiac procedure.

See full Tirofiban drug information
Keep checking

Other Drugs & Red Raspberry

Browse every other medication we’ve checked against Red Raspberry — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
134Moderate
0Minor
2,695No known interaction
Moderate

134 interactions

Showing 60 of 134 moderate interactions — see all 134 on the Red Raspberry page.

No interaction 2,695 drugs checked — show the list
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Red Raspberry and Tirofiban Together: Common Questions

Can you take Red Raspberry with Tirofiban?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Red Raspberry and Tirofiban interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Tirofiban and Red Raspberry?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.