Drug & supplement interaction

Red Raspberry + Clopidogrel

Clopidogrel brand name: Plavix.

Moderate Interaction
Medically reviewed by · Updated October 2026
The bottom line Moderate

Red Raspberry has a moderate interaction with Clopidogrel. Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Red Raspberry and Clopidogrel

Here is the interaction we found between these two, with the evidence behind it.

Moderate

ANTICOAGULANT/ANTIPLATELET DRUGS

Why this applies to Clopidogrel

Clopidogrel falls under ANTICOAGULANT/ANTIPLATELET DRUGS — the group Red Raspberry interacts with.

Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
In vitro research suggests that red raspberry leaf extract has antiplatelet activity and enhances the in vitro effects of the antiplatelet medication cangrelor. This interaction has not been reported in humans.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the short version: clopidogrel (Plavix) is a blood thinner that keeps your platelets from sticking together and forming clots. Red raspberry leaf, in early lab studies, seems to have a mild platelet-blocking effect of its own. The worry is that stacking the two could nudge your bleeding risk a little higher, which might show up as easier bruising, nosebleeds, bleeding gums, or cuts that take longer to stop.

That said, this is theoretical. The concern comes only from test-tube research, not from real people, so we genuinely don't know if it matters in everyday life. An occasional cup of raspberry tea is unlikely to cause trouble. Still, since clopidogrel already affects clotting, I'd mention any regular raspberry leaf supplement use to your pharmacist or doctor first.

Contact Dr. Brian directly if you have additional questions on this interaction
References
  1. Dudzinska D, Bednarska K, Boncler M, Luzak B, Watala C. The influence of Rubus idaeus and Rubus caesius leaf extracts on platelet aggregation in whole blood. Cross-talk of platelets and neutrophils. Platelets. 2016;27(5):433-9.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Red Raspberry Also Interacts With Other Medications

Red Raspberry has 134 moderate known drug interactions in our database — the Clopidogrel one above is one of them. If you take anything else, check it against the full list below.

Moderate 134 No known interaction 2,696 (incl. Clopidogrel)
Taking anything else?

Check Another of Your Medications Against Red Raspberry

Covers the 2,830 medications we’ve checked against Red Raspberry. Pick one to open its full report.

From our Q&A

Questions About Red Raspberry or Clopidogrel

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Red Raspberry or Clopidogrel, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Clopidogrel

This page covers Red Raspberry only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Clopidogrel page lists 309 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Danshen (major), Grapefruit (major), Piracetam (major) and St. John's Wort (major).

By severity: 5 major · 258 moderate · 46 minor.

From our pharmacist’s overview on the Clopidogrel page

“Clopidogrel (Plavix) keeps platelets from sticking together after a stent, heart attack, or stroke, which makes this a list to take carefully. Of the 309 supplements and herbs on file, 202 carry blood-thinning or antiplatelet activity of their own and can stack bleeding risk on top of the drug's, while most of the rest change how the l…”

Reviewed by 2 · Jul 18, 2026

Open the Clopidogrel interaction page

One more smart check

Taking Red Raspberry as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1,303 real supplement products containing Red Raspberry, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Red Raspberry. Your product may carry other ingredients that interact with Clopidogrel too, on top of Red Raspberry — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Red Raspberry and Clopidogrel Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Red Raspberry
Top 25%

#163 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Clopidogrel
Top 1%

#23 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Red Raspberry

What is Red Raspberry?

  • Pregnancy and labor support
  • Menstrual cramps
  • Digestive upset and diarrhea
  • Sore throat and mouth rinse
  • Antioxidant support

Red raspberry leaf is a traditional herbal remedy most often used as a tea in late pregnancy and for menstrual discomfort, but solid scientific evidence for these uses is limited. It is generally considered well tolerated by most adults, but pregnant people should talk with their doctor or midwife before using it.

Read the full Red Raspberry monograph & all interactions
Medication

About Clopidogrel

What Is Clopidogrel Used For?

Brand name: Plavix

Clopidogrel is used to lower the risk of heart attack and stroke in people whose arteries are already affected by disease.

Its supported uses are acute coronary syndrome (including unstable angina, non-ST-elevation heart attack and ST-elevation heart attack), a recent heart attack, a recent stroke, and established peripheral arterial disease (narrowed arteries, usually in the legs). For acute coronary syndrome, some product labels say it should be used together with aspirin.

See full Clopidogrel drug information
Keep checking

Other Drugs & Red Raspberry

Browse every other medication we’ve checked against Red Raspberry — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
134Moderate
0Minor
2,695No known interaction
134 Moderate 2,695 No interaction
Moderate

134 interactions

Showing 60 of 134 moderate interactions — see all 134 on the Red Raspberry page.

No interaction 2,695 drugs checked — show the list

We also checked Red Raspberry against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,695 medications checked with no known interaction — see the full Red Raspberry list.

See the full Red Raspberry interactions page
See every supplement checked against Clopidogrel, ranked by severity
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Red Raspberry monograph › Uses, safety, and every drug interaction in one place Clopidogrel supplement interactions › Every supplement checked against Clopidogrel, ranked by severity Clopidogrel drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Red Raspberry and Clopidogrel Together: Common Questions

Can you take Red Raspberry with Clopidogrel?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Red Raspberry and Clopidogrel interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Clopidogrel and Red Raspberry?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.