Drug & supplement interaction

Swallowroot + Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate

Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate brand name: Plenvu.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated June 2026 · Pair last verified Oct 4, 2026

The bottom line No known interaction

We found no known interaction between Swallowroot and Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Swallowroot and Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate and Swallowroot in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Swallowroot safety at a glance

Swallowroot overall Not established Human safety data are limited, so use cautiously and under professional guidance.

Pregnancy Avoid Not enough safety information exists, so it is best avoided during pregnancy.

Breastfeeding Avoid Safety while breastfeeding is unknown, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate and Swallowroot? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

How we checked

Why No Interaction Is Listed for Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate is filed under a single classification — oral drugs. Swallowroot has documented interactions with 1 drug class — the most serious being anticoagulant/antiplatelet drugs (moderate) — and none of Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Swallowroot Does Interact With Other Medications

Swallowroot has 122 moderate known drug interactions in our database — Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate isn’t one of them. If you take anything else, check it against the full list below.

Moderate 122 No known interaction 2,708 (incl. Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate)

Taking anything else?

Check Another of Your Medications Against Swallowroot

Covers the 2,830 medications we’ve checked against Swallowroot. Pick one to open its full report.

What to actually watch for

What Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate’s Own FDA Label Lists

This is not an interaction — none of it involves Swallowroot. These are the most notable effects listed in the ADVERSE REACTIONS section of Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

Dehydration Worth acting on
Bleeding in the gut Worth acting on
Low potassium Worth acting on
Fainting Worth acting on
An irregular heartbeat Worth acting on
Seizures Worth acting on
Chest pain Worth acting on
Kidney problems Worth acting on
Raised blood pressure Worth acting on
Shortness of breath Worth acting on

Showing the 10 most notable of 33 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate. Read the label on DailyMed › Swallowroot’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Swallowroot side to compare — that is a limit of the record, not a statement that Swallowroot has no side effects.

Everything else you take

See Every Supplement That Interacts With Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate

This page covers Swallowroot only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate page

“Plenvu, the bowel prep combining polyethylene glycol 3350, ascorbic acid, and electrolyte salts to clear the colon before a colonoscopy, carries 17 supplement interactions, and all of them play out in the gut itself. This is a list worth reading carefully rather than skimming.”

Reviewed by 2 · Jul 18, 2026

Open the Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate interaction page

How much people look this up

Where Swallowroot and Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Swallowroot

Top half

#629 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate

Steady interest

#1,858 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Swallowroot reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Swallowroot and Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate records this page draws on were last updated June 22, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Swallowroot

What is Swallowroot?

Digestive complaints
General tonic and appetite stimulant
Blood purifier in folk medicine
Antimicrobial and food preservative
Cooling drink in hot weather

Swallowroot (Decalepis hamiltonii) is a root used in South Indian folk medicine and as a food flavoring, often pickled or made into a cooling drink. Modern scientific evidence for its health benefits in people is very limited, resting mostly on laboratory and animal studies, so its effectiveness is not proven. If you are considering it, talk with your pharmacist or doctor first, especially during pregnancy or breastfeeding.

Decalepis hamiltonii · Apocynaceae · Roots and root tubers · Dried root, root powder, pickles, syrups, and traditional decoctions

An interaction check asks whether these two react with each other — it does not ask whether Swallowroot is a good idea for someone in your situation. Here is what our Swallowroot record says about it on its own.

Swallowroot: dosing

There is no established standardized dose for Swallowroot. Traditional use varies widely depending on whether it is taken as a pickle, a drink, or a powder.If you choose to use a commercial product, follow the directions on the label and do not exceed them.

From our Swallowroot monograph — the full record covers uses, side effects and every documented interaction.

Read the full Swallowroot monograph & all interactions

Medication

About Polyethylene glycol-electrolyte solution (PEG-ES)

What Is Polyethylene glycol-electrolyte solution (PEG-ES) Used For?

Brand name: Plenvu

Polyethylene glycol-electrolyte solution (PEG-ES) is used to empty the colon (large intestine, bowel) before a colonoscopy (examination of the inside of the colon to check for colon cancer and other abnormalities) or barium enema (a test in which the colon is filled with a fluid and then x-rays are taken) so that the doctor will have a clear view of the walls of the colon. PEG-ES is in a class of medications called osmotic laxatives. It works by causing watery diarrhea so that the stool can be emptied from the colon. The medication also contains electrolytes to prevent dehydration and other serious side effects that may be caused by fluid loss as the colon is emptied.

See full Polyethylene glycol-electrolyte solution (PEG-ES) drug information

Keep checking

Other Drugs & Swallowroot

Browse every other medication we’ve checked against Swallowroot — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

122Moderate

0Minor

2,707No known interaction

122 Moderate 2,707 No interaction

Moderate

122 interactions

Showing 60 of 122 moderate interactions — see all 122 on the Swallowroot page.

No interaction 2,707 drugs checked — show the list

We also checked Swallowroot against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,707 medications checked with no known interaction — see the full Swallowroot list.

See the full Swallowroot interactions page

See every supplement checked against Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate, ranked by severity

Evidence & sources

Swallowroot References

The 1 references that drive our Swallowroot monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Suneetha WJ, Krishnakantha TP. Effect of swallowroot extract on functions of platelets in vitro. J Thromb Thrombolysis 2005;19:133-4. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Swallowroot and Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate Together: Common Questions

Is it safe to take Swallowroot with Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate?

We do not list a known interaction between Swallowroot and Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

How was the Swallowroot and Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate combination checked?

Interactions in our licensed database are recorded against drug classes. Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate is filed under 1 classification, and Swallowroot has documented interactions with 1 drug class — none of Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.

Does Swallowroot interact with any other medications?

Yes. Swallowroot has 122 documented drug interactions in our database — Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Does Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate interact with any supplements?

Yes. Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate has documented interactions with 17 supplements in our database — Swallowroot is not one of them. The Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Swallowroot monograph Uses, safety profile, and every drug interaction in one place Polyethylene glycol-electrolyte solution (PEG-ES) drug information The full plain-English guide to this medication Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate supplement interactions Every supplement checked against Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Ascorbic Acid, Polyethylene Glycol 3350, Potassium Chloride, Sodium Ascorbate, Sodium Chloride, Sodium Sulfate and Swallowroot?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.