Swallowroot + Enoxaparin
Enoxaparin brand name: Lovenox.
Swallowroot has a moderate interaction with Enoxaparin. Theoretically, swallowroot might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full interaction reportSwallowroot and Enoxaparin
Here is the interaction we found between these two, with the evidence behind it.
ANTICOAGULANT/ANTIPLATELET DRUGS
Why this applies to Enoxaparin
Enoxaparin falls under ANTICOAGULANT/ANTIPLATELET DRUGS — the group Swallowroot interacts with.
In vitro research shows that swallowroot inhibits platelet aggregation.
Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
Enoxaparin (Lovenox) is already a strong blood thinner, given as an injection to stop clots from forming. Swallowroot is interesting here because lab studies suggest it can make platelets (the tiny cells that help your blood clump together) less sticky. Stack that mild blood-thinning hint on top of a medication that's deliberately thinning your blood, and the worry is simply more bleeding.
In real life that could look like easier bruising, nosebleeds, bleeding gums, or longer bleeding from a small cut. I want to be honest, though: this concern comes only from test-tube and animal research, not from people, so it's theoretical. Pickled or flavored food amounts likely matter far less than concentrated supplement doses. Before combining them, please check with your doctor or pharmacist.
- Suneetha WJ, Krishnakantha TP. Effect of swallowroot extract on functions of platelets in vitro. J Thromb Thrombolysis 2005;19:133-4. PubMed
What These Ratings Mean
Every interaction above is graded three ways — here’s the key to each label.
Clinically significant. Avoid the combination, or use only under close professional supervision.
Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.
Generally not serious. Be aware of it and mention it to your pharmacist.
- LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
- ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
- UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
- AHigh-quality meta-analysis (quantitative systematic review).
- BCase-control study.
- CConsensus.
- DAnecdotal evidence.
These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.
Swallowroot Also Interacts With Other Medications
Swallowroot has 121 moderate known drug interactions in our database — the Enoxaparin one above is one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Swallowroot
We haven’t checked that one against Swallowroot yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Swallowroot. Pick one to open its full report.
See Every Supplement That Interacts With Enoxaparin
This page covers Swallowroot only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Enoxaparin page lists 202 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Danshen (major), Piracetam (major), Aconite (moderate), Allspice (moderate) and Aloe (moderate).
By severity: 2 major · 183 moderate · 17 minor.
From our pharmacist’s overview on the Enoxaparin page
“If you are giving yourself enoxaparin (Lovenox) shots after surgery or to treat a clot, read this page with real care. All 202 supplement ingredients on file pull on the same thread, bleeding.”
Reviewed by 2 · Jul 18, 2026
Where Swallowroot and Enoxaparin Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,129 of 1,452 supplements looked up here in the last 7 days
#1,634 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
About Swallowroot
What is Swallowroot?
- Digestive complaints
- General tonic and appetite stimulant
- Blood purifier in folk medicine
- Antimicrobial and food preservative
- Cooling drink in hot weather
Swallowroot (Decalepis hamiltonii) is a root used in South Indian folk medicine and as a food flavoring, often pickled or made into a cooling drink. Modern scientific evidence for its health benefits in people is very limited, resting mostly on laboratory and animal studies, so its effectiveness is not proven. If you are considering it, talk with your pharmacist or doctor first, especially during pregnancy or breastfeeding.
About Enoxaparin Injection
What Is Enoxaparin Injection Used For?
Brand name: Lovenox
Enoxaparin injection is used to prevent deep vein thrombosis (DVT) — blood clots in the legs — in people having abdominal surgery, hip replacement surgery, or knee replacement surgery, and in hospitalized patients who are largely immobile due to acute illness. It is also used to treat acute DVT, with or without a pulmonary embolism (a clot in the lungs), both in the hospital and at home.
It is also used alongside aspirin to reduce dangerous complications of unstable angina and non-Q-wave heart attack, and to treat acute STEMI (a severe type of heart attack involving full blockage of a coronary artery) in patients who receive clot-dissolving therapy or undergo a procedure to open the blocked artery (PCI).
Other Drugs & Swallowroot
Browse every other medication we’ve checked against Swallowroot — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
121 interactions
- Diclofenac Sodium ›
- Ibuprofen ›
- Aspirin ›
- Naproxen ›
- Minocycline ›
- Diclofenac Potassium ›
- Dipyridamole ›
- Ketoprofen ›
- Bivalirudin ›
- Warfarin Sodium ›
- Bromfenac Sodium ›
- Dabigatran ›
- Diclofenac Epolamine ›
- Iloprost ›
- Piroxicam ›
- Streptokinase ›
- Ticlopidine ›
- Treprostinil (oral) ›
- Abciximab ›
- Abrocitinib ›
- Acenocoumarol ›
- Acetylsalicylic Acid ›
- Anacaulase-bcdb ›
- Anagrelide ›
- Anisindione ›
- Antithrombin Iii ›
- Apixaban ›
- Argatroban ›
- Betrixaban ›
- Cablivi ›
- Cangrelor ›
- Cilostazol ›
- Clopidogrel ›
- Dalteparin ›
- Danaparoid ›
- Defibrotide Sodium ›
- Diclofenac ›
- Dicumarol ›
- Edoxaban ›
- Effient ›
- Eptifibatide ›
- Fish Oil Triglycerides ›
- Fondaparinux ›
- Heparin ›
- Ibrutinib ›
- Ibuprofen Lysine ›
- Icosapent Ethyl (prescription Drug) ›
- Inotersen ›
- Lepirudin ›
- Nadroparin ›
- Naproxen Sodium ›
- Nintedanib Esylate ›
- Nusinersen Sodium ›
- Omega-3 Fatty Acids (prescription Drug) ›
- Pazopanib ›
- Pentoxifylline ›
- Phenprocoumon ›
- Reteplase ›
- Rivaroxaban ›
- Selexipag ›
Showing 60 of 121 moderate interactions — see all 121 on the Swallowroot page.
No interaction 2,708 drugs checked — show the list
We also checked Swallowroot against these medications and found no known interaction in our sources. Open any page to confirm.
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Ivermectin ›
- Rosuvastatin ›
- Escitalopram ›
- Tadalafil ›
- Acetaminophen ›
- Valacyclovir ›
- Atorvastatin ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Sumatriptan ›
- Semaglutide ›
- Tirzepatide ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Acyclovir ›
- Bupropion ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Lamotrigine ›
- Fluoxetine ›
- Methotrexate ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Amphetamine ›
- Pregabalin ›
- Isotretinoin ›
- Dextroamphetamine ›
- Azithromycin ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Amlodipine Besylate ›
- Methylene Blue ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
- Bisoprolol ›
- Levothyroxine, Liothyronine ›
- Acetaminophen, Oxycodone ›
- Dapsone ›
- Diazepam ›
- Cyclopentolate ›
- Candesartan Cilexetil ›
- Mannitol ›
Showing the 60 most looked-up of 2,708 medications checked with no known interaction — see the full Swallowroot list.
Sources & How We Checked
Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference for vitamins, herbs and supplements — the basis for our interaction data.
- MedlinePlus, U.S. National Library of Medicine — NIH consumer drug information, used for the medication overviews.
- NIH Dietary Supplement Label Database (DSLD) — Official supplement product labels.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Enoxaparin Is Linked to Lower Levels of One Nutrient
Natural Medicines records Enoxaparin as a medicine that can lower these. This is not an interaction with Swallowroot — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Enoxaparin nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Swallowroot and Enoxaparin Together: Common Questions
Can you take Swallowroot with Enoxaparin?
How serious is the Swallowroot and Enoxaparin interaction?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Still Have a Question About Enoxaparin and Swallowroot?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.