Drug & supplement interaction

Uzara + Ferric Carboxymaltose

Ferric Carboxymaltose brand name: Injectafer.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Uzara and Ferric Carboxymaltose in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

Know someone taking this? Share
Interaction report

Uzara and Ferric Carboxymaltose

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ferric Carboxymaltose and Uzara in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Uzara safety at a glance

Uzara overall Use caution It contains heart-active compounds and should only be used short-term and with professional guidance.
Pregnancy Avoid Safety is not established, so it is best avoided during pregnancy.
Breastfeeding Avoid There is not enough safety information, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ferric Carboxymaltose and Uzara? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
Keep it in perspective

Uzara Does Interact With Other Medications

Uzara has 1 major, 132 moderate known drug interactions in our database — Ferric Carboxymaltose isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Uzara

Covers the 2,830 medications we’ve checked against Uzara. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Uzara and Ferric Carboxymaltose May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Raised blood pressure Worth acting on Additional detail

    Uzara

    “Orally, uzara can cause cardiotoxic effects, especially in patients with pre-existing cardiovascular disease. In one case report, a 68-year-old female with diabetes and hypertension was admitted to the emergency room with reduced left-ventricular function, pulmonary edema, and arrhythmia.”

    Uzara · Natural Medicines adverse-effect record, reported in arrhythmia.

    1 source cited
    1. 99461. Thürmann PA, Neff A, Fleisch J. Interference of Uzara glycosides in assays of digitalis glycosides. Int J Clin Pharmacol Ther. 2004;42(5):281-4. PubMed

    Ferric Carboxymaltose

    Listed in the ADVERSE REACTIONS section of the FDA label for Ferric Carboxymaltose. Read the label on DailyMed ›

  • Swelling Additional detail

    Uzara

    Recorded for Uzara in the same Natural Medicines adverse-effect record shown under Raised blood pressure above.

    Ferric Carboxymaltose

    Listed in the ADVERSE REACTIONS section of the FDA label for Ferric Carboxymaltose. Read the label on DailyMed ›

Reported for Uzara but not commonly for Ferric Carboxymaltose: an irregular heartbeat.

Effects for Ferric Carboxymaltose come from the ADVERSE REACTIONS section of its FDA label; effects for Uzara come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 1,619 voluntary FDA FAERS reports for Ferric Carboxymaltose that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

How much people look this up

Where Uzara and Ferric Carboxymaltose Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Uzara
Steady interest

#1,005 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ferric Carboxymaltose
Top 25%

#446 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Uzara reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Uzara and Ferric Carboxymaltose records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Uzara

What is Uzara?

  • Diarrhea
  • Stomach cramps
  • Menstrual cramps (dysmenorrhea)
  • Headaches
  • Digestive upset

Uzara is a traditional African root remedy used mainly for diarrhea and stomach cramps. Because it contains cardiac glycosides that can affect the heart, it should be used cautiously and for short periods only. Talk to a pharmacist or doctor before using it, especially if you have heart problems, are pregnant, or take heart medications.

Xysmalobium undulatum · Apocynaceae · Dried root · Liquid extract, tincture, tablets, drops

An interaction check asks whether these two react with each other — it does not ask whether Uzara is a good idea for someone in your situation. Here is what our Uzara record says about it on its own.

Uzara: dosing

There is no well-established standard dose for Uzara, and products vary in strength. The right amount depends on the specific preparation, such as drops, tincture, or tablets.The safest approach is to follow the directions on the product label and use it only for short periods. Do not exceed the recommended amount, since higher doses raise the risk of heart-related side effects.

From our Uzara monograph — the full record covers uses, side effects and every documented interaction.

Read the full Uzara monograph & all interactions
Medication

About Ferric Carboxymaltose Injection

What Is Ferric Carboxymaltose Injection Used For?

Brand name: Injectafer

Ferric carboxymaltose injection treats iron deficiency anemia (IDA) in adults and children aged 1 year and older who cannot tolerate oral iron or haven't responded well to it. It is also approved for adults with non-dialysis dependent chronic kidney disease who have iron deficiency anemia.

Additionally, ferric carboxymaltose injection is used in adults with heart failure (New York Heart Association class II or III) who have iron deficiency — specifically to help improve their ability to exercise.

Most-Reported Side Effects for Ferric Carboxymaltose

From FAERS, the FDA’s public side-effect reporting system (1,619 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Hypophosphataemia 563 reports
Product quality issue 226 reports
Anxiety 202 reports
Emotional distress 198 reports
Anhedonia 197 reports
See full Ferric Carboxymaltose Injection drug information
Keep checking

Other Drugs & Uzara

Browse every other medication we’ve checked against Uzara — both the ones with a known interaction and the ones without. Select any drug for the full detail.

1Major
132Moderate
0Minor
2,696No known interaction
Major

1 interaction

Moderate

132 interactions

Showing 60 of 132 moderate interactions — see all 132 on the Uzara page.

No interaction 2,696 drugs checked — show the list
Evidence & sources

Uzara References

The 7 references that drive our Uzara monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Burnham TH, ed. Drug Facts and Comparisons, Updated Monthly. Facts and Comparisons, St. Louis, MO.
  5. Abd-El-Maeboud KH, Kortam MA, Ali MS, Ibrahim MI, Mohamed RM. A preliminary pilot randomized crossover study of uzara (Xysmalobium undulatum) versus ibuprofen in the treatment of primary dysmenorrhea. PLoS One. 2014;9(8):e104473. PubMed
  6. Schmiedl S, Ritter A, Szymanski J, et al. Cardiovascular effects, pharmacokinetics and cross-reactivity in digitalis glycoside immunoassays of an antidiarrheal uzara root extract. Int J Clin Pharmacol Ther. 2012;50(10):729-40. PubMed
  7. Thürmann PA, Neff A, Fleisch J. Interference of Uzara glycosides in assays of digitalis glycosides. Int J Clin Pharmacol Ther. 2004;42(5):281-4. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Uzara and Ferric Carboxymaltose Together: Common Questions

Is it safe to take Uzara with Ferric Carboxymaltose?
We do not list a known interaction between Uzara and Ferric Carboxymaltose. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Uzara and Ferric Carboxymaltose have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Uzara interact with any other medications?
Yes. Uzara has 133 documented drug interactions in our database — Ferric Carboxymaltose is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Ferric Carboxymaltose and Uzara?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.