Vanadium + Granisetron
Granisetron brand names: Kytril, Sustol.
We found no known interaction between Vanadium and Granisetron in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Granisetron states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Vanadium and Granisetron
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Granisetron and Vanadium in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Vanadium safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Granisetron
Interactions in our licensed database are recorded against drug classes, not just single drug names. Granisetron is filed under 3 classifications — serotonergic drugs, serotonergic drugs, oral drugs. Vanadium has documented interactions with 2 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate) and antidiabetes drugs (moderate) — and none of Granisetron’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Vanadium Does Interact With Other Medications
Vanadium has 208 moderate known drug interactions in our database — Granisetron isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Vanadium
We haven’t checked that one against Vanadium yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Vanadium. Pick one to open its full report.
Vanadium in Pregnancy & Breastfeeding
When used orally in amounts found in foods.
When used orally in medicinal amounts. Epidemiological research has found that increased urinary levels of vanadium are associated with an increased risk of both term and preterm premature rupture of membranes (PROM). When comparing tertiles of urinary vanadium levels, patients in the middle tertile had 1.66 times the risk of term PROM when compared with the lowest tertile, and those in the highest tertile had 3.75 times the risk. For preterm PROM (rupture prior to 37 weeks' gestation), those in the highest tertile had an 8.14 times increased risk when compared with those in the lowest tertile. Epidemiological research has also found that higher prenatal serum levels of vanadium are associated with impaired fetal growth, particularly in male newborns. The risk appears greatest with vanadium exposure in the second trimester.
When used orally in amounts found in foods. There is insufficient reliable information available about the safety of vanadium when used in amounts greater than those typically found in foods; avoid using.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
Some Granisetron Products Have a Food Rule — Vanadium Should Not Break It
At least one FDA label for a product containing Granisetron says to take it on an empty stomach. Most supplements — Vanadium included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Granisetron on its own and move Vanadium to a meal later in the day.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Granisetron products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
Recommended Dosage ( 2.2 ): The recommended dosage in adults is 10 mg administered as a single subcutaneous injection at least 30 minutes before the start of emetogenic chemotherapy on Day 1.
From the Dosage and Administration section of the FDA label we read for Granisetron — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
What Granisetron Is Prescribed For, and What Vanadium Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Granisetron is a prescription medicine with approved uses on its FDA label. Vanadium is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.
Granisetron is prescribed for: Granisetron is used to prevent nausea and vomiting linked to emetogenic (nausea-causing) cancer chemotherapy — including high-dose cisplatin — and radiation therapy, including total body irradiation and fractionated abdominal radiation. Granisetron hydrochloride tablets and Granisol oral solution are approved for both the chemotherapy and radiation indications. Sancuso skin patch is approved for prevention of nausea and vomiting in adults receiving moderately and/or highly emetogenic chemotherapy regimens of up to 5 consecutive days. Granisetron hydrochloride injection (intravenous) is also used to prevent and treat postoperative nausea and vomiting in adults.
Read the rest of what Granisetron is prescribed for
Sustol (subcutaneous injection) is used in combination with other anti-nausea medicines in adults specifically for the prevention of acute and delayed nausea and vomiting associated with moderately emetogenic chemotherapy or anthracycline and cyclophosphamide combination chemotherapy regimens.
Vanadium has been studied for:
-
Cancer studied, not established Vanadium has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Vanadium for cancer
Although there has been interest in using oral vanadium for cancer, there is insufficient reliable information about the clinical effects of vanadium for this purpose.
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Granisetron on your own; if you are taking Vanadium for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
See Every Supplement That Interacts With Granisetron
This page covers Vanadium only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Granisetron page lists 38 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Lithium (major), 5-htp (moderate), Acetyl-l-carnitine (moderate) and Ayahuasca (moderate).
By severity: 2 major · 25 moderate · 11 minor.
From our pharmacist’s overview on the Granisetron page
“Granisetron (Kytril, Sustol) blocks serotonin signals to stop nausea from chemotherapy and surgery, and this is a list that warrants real caution before you add a supplement to it. Most of the entries raise serotonin themselves, and stacking them on a serotonin-acting drug can push toward serotonin syndrome, a dangerous overload of tha…”
Reviewed by 2 · Jul 18, 2026
Taking Vanadium as Part of a Dietary Supplement Product? Check It for Interactions
We hold 4,701 real supplement products containing Vanadium, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Vanadium. Even though Vanadium itself has no known interaction with Granisetron, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Vanadium and Granisetron Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#51 of 1,452 supplements looked up here in the last 7 days
#2,614 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Vanadium reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Vanadium and Granisetron records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Vanadium
What is Vanadium?
- Blood sugar and diabetes support
- Athletic performance and muscle building
- Lowering cholesterol
- General trace-mineral supplementation
Vanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athletic performance are not well proven, and higher doses can be toxic. Most people do not need to supplement it, and you should check with your doctor or pharmacist before using it.
Trace mineral (not a plant); supplements use vanadium salts such as vanadyl sulfate or sodium metavanadate · Capsules, tablets, often as vanadyl sulfate; sometimes in multivitamin or sports supplements
An interaction check asks whether these two react with each other — it does not ask whether Vanadium is a good idea for someone in your situation. Here is what our Vanadium record says about it on its own.
Vanadium: dosing
There is no established standard supplement dose for vanadium, and there is no recognized daily requirement for it as a separate supplement because the diet provides what the body needs. Studies in diabetes used high doses that are not considered safe for general use.If you choose to take a product, follow the directions on the label and do not exceed them.
From our Vanadium monograph — the full record covers uses, side effects and every documented interaction.
About Granisetron
What Is Granisetron Used For?
Brand names: Kytril, Sustol
Granisetron is used to prevent nausea and vomiting linked to emetogenic (nausea-causing) cancer chemotherapy — including high-dose cisplatin — and radiation therapy, including total body irradiation and fractionated abdominal radiation. Granisetron hydrochloride tablets and Granisol oral solution are approved for both the chemotherapy and radiation indications. Sancuso skin patch is approved for prevention of nausea and vomiting in adults receiving moderately and/or highly emetogenic chemotherapy regimens of up to 5 consecutive days.
Granisetron hydrochloride injection (intravenous) is also used to prevent and treat postoperative nausea and vomiting in adults. Sustol (subcutaneous injection) is used in combination with other anti-nausea medicines in adults specifically for the prevention of acute and delayed nausea and vomiting associated with moderately emetogenic chemotherapy or anthracycline and cyclophosphamide combination chemotherapy regimens.
Other Drugs & Vanadium
Browse every other medication we’ve checked against Vanadium — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
208 interactions
- Diclofenac Sodium ›
- Ibuprofen ›
- Aspirin ›
- Insulin (rdna) ›
- Naproxen ›
- Minocycline ›
- Glyburide ›
- Insulin (pork) ›
- Diclofenac Potassium ›
- Dipyridamole ›
- Insulin (human) ›
- Ketoprofen ›
- Acarbose ›
- Bivalirudin ›
- Insulin Glargine ›
- Semaglutide ›
- Warfarin Sodium ›
- Bromfenac Sodium ›
- Chlorpropamide ›
- Dabigatran ›
- Diclofenac Epolamine ›
- Exenatide ›
- Glipizide ›
- Glucagon ›
- Iloprost ›
- Insulin Lispro ›
- Metformin ›
- Piroxicam ›
- Repaglinide ›
- Sitagliptin ›
- Streptokinase ›
- Ticlopidine ›
- Tirzepatide ›
- Treprostinil (oral) ›
- Abciximab ›
- Abrocitinib ›
- Acenocoumarol ›
- Acetohexamide ›
- Acetylsalicylic Acid ›
- Albiglutide ›
- Alogliptin ›
- Anacaulase-bcdb ›
- Anagrelide ›
- Anisindione ›
- Antithrombin Iii ›
- Apixaban ›
- Argatroban ›
- Betrixaban ›
- Cablivi ›
- Canagliflozin ›
- Cangrelor ›
- Cilostazol ›
- Clopidogrel ›
- Dalteparin ›
- Danaparoid ›
- Dapagliflozin ›
- Dasiglucagon Hydrochloride ›
- Defibrotide Sodium ›
- Diclofenac ›
- Dicumarol ›
Showing 60 of 208 moderate interactions — see all 208 on the Vanadium page.
No interaction 2,621 drugs checked — show the list
We also checked Vanadium against these medications and found no known interaction in our sources. Open any page to confirm.
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Metoprolol ›
- Acetaminophen ›
- Rosuvastatin ›
- Escitalopram ›
- Abemaciclib ›
- Tadalafil ›
- Atorvastatin ›
- Docusate ›
- Valacyclovir ›
- Methamphetamine ›
- Hydroxyurea ›
- Sumatriptan ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Lisinopril ›
- Amoxicillin ›
- Bupropion ›
- Amitriptyline ›
- Methotrexate ›
- Bendamustine ›
- Acyclovir ›
- Doxycycline ›
- Fluoxetine ›
- Amphetamine ›
- Lamotrigine ›
- Pregabalin ›
- Azithromycin ›
- Isotretinoin ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Dextroamphetamine ›
- Amlodipine Besylate ›
- Methylene Blue ›
- Clonazepam ›
- Omeprazole ›
- Quetiapine ›
- Letrozole ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
- Bisoprolol ›
- Levothyroxine, Liothyronine ›
- Acetaminophen, Oxycodone ›
- Diazepam ›
- Candesartan Cilexetil ›
- Dapsone ›
- Cephalexin ›
- Cyclopentolate ›
- Acetaminophen, Dextromethorphan, Doxylamine ›
- Mannitol ›
- Roxithromycin ›
Showing the 60 most looked-up of 2,621 medications checked with no known interaction — see the full Vanadium list.
Vanadium References
The 15 references that drive our Vanadium monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Harland BF, Harden-Williams BA. Is vanadium of human nutritional importance yet? J Am Diet Assoc 1994;94:891-4. PubMed
- Sitprija V, Tungsanga K, Tosukhowong P, et al. Metabolic problems in northeastern Thailand: possible role of vanadium. Mineral Electrolyte Metab 1998;19:51-6.
- Funakoshi T, Shimada H, Kojima S, et al. Anticoagulant action of vanadate. Chem Pharmaceut Bull 1992;40:174-6. PubMed
- Halberstam M, Cohen N, Shlimovich P, et al. Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes 1996;45:659-66. PubMed
- Cohen N, Halberstam M, Shlimovich P, et al. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J Clin Invest 1995;95:2501-9. PubMed
- Boden G, Chen X, Ruiz J, et al. Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus. Metabolism 1996;45:1130-5.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Goldfine AB, Simonson DC, Folli F, et al. Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies. J Clin Endocrinol Metab 1995;80:3311-20. PubMed
- Cusi K, Cukier S, DeFronzo RA, et al. Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type 2 diabetes. J Clin Endocrinol Metab 2001;86:1410-7.
- Peat F, Coomber R, Rana A, Vince A. Vanadium allergy following total knee arthroplasty. BMJ Case Rep 2018;2018. pii: bcr-2017-222092. doi: 10.1136/bcr-2017-222092. PubMed
- Jin S, Xia W, Jiang Y, et al. Urinary vanadium concentration in relation to premature rupture of membranes: A birth cohort study. Chemosphere 2018;210:1035-41. doi: 10.1016/j.chemosphere.2018.07.110. PubMed
- Garcia-Nunez I, Algaba-Marmol MA, Suarez-Vergara M, et al. Vanadium contact dermatitis: case report and studies performed. Contact Dermatitis 2019;80(2):127-8. PubMed
- Zhou Y, Zhu Q, Ma W, et al. Prenatal vanadium exposure, cytokine expression, and fetal growth: a gender-specific analysis in Shanghai MCPC study. Sci Total Environ 2019;685:1152-9. PubMed
- Jiang S, Zhou S, Liu H, et al. Concentrations of vanadium in urine with hypertension prevalence and blood pressure levels. Ecotoxicol Environ Saf 2021;213:112028. PubMed
- Zhang W, Chen H, Zeng Q, Xu S, Xia W, Li Y. Prenatal and postnatal exposure to vanadium and the immune function of children. J Trace Elem Med Biol 2021;67:126787. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Vanadium and Granisetron Together: Common Questions
Is it safe to take Vanadium with Granisetron?
Do Vanadium and Granisetron have any of the same side effects?
Should I take Vanadium and Granisetron at the same time of day?
Are Vanadium and Granisetron used for the same thing?
How was the Vanadium and Granisetron combination checked?
Does Vanadium interact with any other medications?
Does Granisetron interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.