Yarrow + Pimozide
Pimozide brand name: Orap.
We found no known interaction between Yarrow and Pimozide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Yarrow and Pimozide
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Pimozide and Yarrow in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Yarrow safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Pimozide
Interactions in our licensed database are recorded against drug classes, not just single drug names. Pimozide is filed under 6 classifications — including antipsychotic drugs, qt interval-prolonging drugs, anticholinergic drugs. Yarrow has documented interactions with 1 drug class — the most serious being lithium (moderate) — and none of Pimozide’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Yarrow Does Interact With Other Medications
Yarrow has 1 moderate known drug interaction in our database — Pimozide isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Yarrow
We haven’t checked that one against Yarrow yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Yarrow. Pick one to open its full report.
Yarrow in Pregnancy & Breastfeeding
When used orally; yarrow is believed to be an abortifacient and affect the menstrual cycle.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
See Every Supplement That Interacts With Pimozide
This page covers Yarrow only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Pimozide page lists 180 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).
By severity: 12 major · 127 moderate · 41 minor.
From our pharmacist’s overview on the Pimozide page
“Pimozide (Orap), prescribed mainly for severe tics in Tourette syndrome, is a medicine I ask patients to check every supplement against before adding it. Twelve of the 180 ingredients on file rate major, and most of the risk runs through one pathway: 121 of them affect CYP3A4, the enzyme that clears pimozide.”
Reviewed by 2 · Jul 18, 2026
Taking Yarrow as Part of a Dietary Supplement Product? Check It for Interactions
We hold 600 real supplement products containing Yarrow, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Yarrow. Even though Yarrow itself has no known interaction with Pimozide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Yarrow and Pimozide Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#279 of 1,452 supplements looked up here in the last 7 days
#1,820 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Yarrow reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Yarrow and Pimozide records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Yarrow
What is Yarrow?
- Wounds and minor bleeding
- Digestive upset and cramping
- Colds, flu, and fever
- Skin conditions
- Menstrual discomfort
Yarrow is a traditional herb long used for wounds, digestive complaints, and colds, but high-quality human studies are very limited, so its benefits are not well proven. It is generally used short-term, and people who are pregnant, breastfeeding, or allergic to ragweed and related plants should avoid it.
Achillea millefolium · Asteraceae · Aerial parts (leaves, flowers, and stems) and essential oil · Tea, tincture, capsules, dried herb, topical creams or ointments, and essential oil
An interaction check asks whether these two react with each other — it does not ask whether Yarrow is a good idea for someone in your situation. Here is what our Yarrow record says about it on its own.
Yarrow: dosing
There is no official, standardized dose for yarrow. Traditional use includes teas made from the dried herb, tinctures, and capsules, as well as creams applied to the skin.Because product strengths vary widely, the safest approach is to follow the directions on the product label and not exceed them. Yarrow is intended for short-term use, not long-term daily use.
From our Yarrow monograph — the full record covers uses, side effects and every documented interaction.
About Pimozide
What Is Pimozide Used For?
Brand name: Orap
Pimozide tablets are used to suppress motor tics (involuntary movements) and phonic tics (involuntary sounds or words) in people with Tourette's Disorder. It is reserved for patients whose daily life or development is severely affected by their tics — it is not intended as a first-line treatment, and it is not used for tics that are mild or mainly cosmetic concerns.
Pimozide is not meant for tics caused by other conditions or medications, and it should not be used for simple tics unrelated to Tourette's Disorder.
Most-Reported Side Effects for Pimozide
From FAERS, the FDA’s public side-effect reporting system (471 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Yarrow
Browse every other medication we’ve checked against Yarrow — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
1 interaction
No interaction 2,828 drugs checked — show the list
We also checked Yarrow against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Losartan Potassium ›
- Testosterone ›
- Ivermectin ›
- Abemaciclib ›
- Metoprolol ›
- Aspirin ›
- Acetaminophen ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Warfarin Sodium ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Lisinopril ›
- Amitriptyline ›
- Amoxicillin ›
- Isotretinoin ›
- Methotrexate ›
- Amlodipine Besylate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Fluoxetine ›
- Doxycycline ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Citalopram ›
- Buspirone ›
Showing the 60 most looked-up of 2,828 medications checked with no known interaction — see the full Yarrow list.
Yarrow References
The 8 references that drive our Yarrow monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
- Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
- Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
- Becker LC, Bergfeld WF, Belsito DV, et al. Safety assessment of Achillea millefolium as used in cosmetics. Int J Toxicol. 2016;35(3 suppl):5S-15S.
- Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed
- de Souza P, Crestani S, da Silva Rde C, et al. Involvement of bradykinin and prostaglandins in the diuretic effects of Achillea millefolium L. (Asteraceae). J Ethnopharmacol. 2013 Aug 26;149(1):157-61. PubMed
- Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani M. Effect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial. Eur J Oncol Nurs. 2015;19(3):207- PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Yarrow and Pimozide Together: Common Questions
Is it safe to take Yarrow with Pimozide?
Do Yarrow and Pimozide have any of the same side effects?
How was the Yarrow and Pimozide combination checked?
Does Yarrow interact with any other medications?
Does Pimozide interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.