Yin Chen - Amitriptyline, Chlordiazepoxide Interaction
Herbal: Yin Chen
Also Known As: Armoise à Balais, Armoise Capillaire, Artemisia Officinalis, Capillary Wormwood, Ceinture de Saint-Jean, Chiu, Couronne de Saint-Jean, In Chen, Inchin-Ko-To, Inchinko, Injin, Kyunchinho, Rumput Roman, Artemisia capillaris
Drug: Amitriptyline, Chlordiazepoxide
Brand names:
Limbitrol DS

Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 04, 2025
Interaction Details
Amitriptyline, Chlordiazepoxide is classified as belonging to the following category: Cns Depressants
Theoretically, yin chen might enhance the therapeutic and adverse effects of other CNS depressants.
Animal research shows that yin chen has sedative effects and can reduce motor activity and impair balance and coordination. When used in combination with pentobarbital, yin chen increases sleeping time when compared to pentobarbital alone.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- dela Peña IJ, Hong E, Kim HJ, et al. Artemisia capillaris thunberg produces sedative-hypnotic effects in mice, which are probably mediated through potentiation of the GABAA receptor. Am J Chin Med. 2015;43(4):667-79.
Yin Chen Overview

Yin Chen - More Interactions
Yin Chen interacts with 247 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
Unknown | No interactions have been reported or no interaction data is currently available. |
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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Drug descriptions are provided by MedlinePlus.