Acidophilus & Bifidus Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Acidophilus & Bifidus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Acidophilus & Bifidus is a dietary supplement by Lake Avenue Nutrition with 3 active ingredients. Its ingredients are commonly taken for digestive health and regularity, irritable bowel syndrome (ibs), diarrhea (including antibiotic-related).Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium longum BL-5, Lactobacillus acidophilus LA-14. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Acidophilus & Bifidus by Lake Avenue Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with Acidophilus & Bifidus by Lake Avenue Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Acidophilus & Bifidus by Lake Avenue Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product has three active probiotic ingredients—beneficial bacteria strains that support your gut. Two of them, Bifidobacterium longum and Lactobacillus acidophilus, are named specifically; the third is part of a probiotic blend.
The capsules also contain inactive ingredients like cellulose, a film coating, and silica for flow and stability.
Does it work?
Moderate evidence
The evidence for what these probiotics do varies by strain and condition. Lactobacillus acidophilus has possibly effective ratings for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.
Bifidobacterium longum, on the other hand, lacks enough reliable evidence to rate it for the conditions studied—these include age-related cognitive decline, hay fever, antibiotic-associated diarrhea, anxiety, asthma, and athletic performance. We don't have effectiveness data on file for the third ingredient.
How safe is it?
Well-documented data
Both checked strains are generally well tolerated in healthy adults and children. However, caution is advised if you're seriously ill or have a compromised immune system—there are rare reports of these bacteria causing blood infections (bacteremia) in critically ill patients, including infants.
When taken by mouth, uncommon side effects include stomach discomfort, pain, bloating, flatulence, and occasionally constipation or diarrhea. One person reported a dry cough in a clinical trial.
Safety data during breastfeeding are limited, so check with your doctor or pharmacist before using while nursing. For pregnancy, the data suggest it's possibly safe, but you'll want to confirm with your healthcare provider.
Meds to double-check
Moderate interaction found
Antibiotic drugs are the main medications you'll want to double-check before taking this product. The live bacteria in it may be killed if you take them at the same time, reducing the probiotic's effectiveness.
Separate your antibiotic and this supplement by several hours, and ask your pharmacist or doctor for the spacing that works best.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This probiotic blend may help with IBS, diarrhea linked to antibiotics, or other conditions where Lactobacillus acidophilus has shown promise. If you're taking antibiotics, space this supplement several hours away from your doses.
Anyone who's seriously ill, has a weakened immune system, or is pregnant or breastfeeding should talk with their doctor or pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Acidophilus & Bifidus, straight from the product label.
| Brand | Lake Avenue Nutrition |
|---|---|
| Barcode (UPC) | 898220014132 |
| Net contents | 180 Veggie Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2022 |
| DSLD ID | 274390 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Acidophilus & Bifidus by Lake Avenue Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Bifidobacterium animalis lactis BL-04 | 0 NP | -- |
| Bifidobacterium longum BL-5 | 0 NP | -- |
| Lactobacillus acidophilus LA-14 | 0 NP | -- |
| Blend of Probiotic Bacteria | 0 NP | -- |
Other ingredients: Microcrystalline Cellulose, Hypromellose, Stearic Acid, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: Take 1 capsule daily with or without food, or as recommended by a healthcare practitioner.
Formulation
Formulated without: GMOs, gluten or soy.
Natural color variation may occur.
Supports intestinal flora and digestion
Not manufactured with milk, egg, fish, shellfish, tree nuts, peanuts, wheat, soy or gluten.
Precautions
Warnings: Keep out of reach of children.
As with all dietary supplements, it is recommended to consult with a healthcare professional before adding something new to your health and wellness regime. Do not eat freshness packet, keep in bottle. Sealed for your protection, do not use if seal is missing or broken.
Not manufactured with milk, egg, fish, shellfish, tree nuts, peanuts, wheat, soy or gluten. Produced in a third-party GMP facility that may process other products that contain these allergens or ingredients.
Storage
May be stored at room temperature. Refrigerate after opening to maintain potency.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Formula
Acidophilus & Bifidus 8 billion CFU
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Acidophilus & Bifidus by Lake Avenue Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Acidophilus & Bifidus by Lake Avenue Nutrition
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Blend of Probiotic Bacteria
- › Bifidobacterium animalis lactis BL-04
- › Bifidobacterium longum BL-5
- › Lactobacillus acidophilus LA-14
Other (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, Stearic Acid, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Acidophilus & Bifidus by Lake Avenue Nutrition Drug Interactions
HelloPharmacist Interaction Report
Lake Avenue Nutrition's Acidophilus & Bifidus contains three live bacterial strains.
Two of them—Bifidobacterium longum and Lactobacillus acidophilus—have a documented interaction with antibiotic drugs. When you take antibiotics at the same time as either strain, the antibiotics may kill off a significant portion of the live organisms in the supplement, which could reduce how well the probiotic works.
The interaction is rated Moderate for both.
Read the full breakdown — every affected drug type, severity by severity
To minimize this effect, you'll want to space out when you take your antibiotics and this probiotic. Most guidance suggests taking them several hours apart—ask your pharmacist or doctor for the timing that works best for your specific antibiotic.
Altogether, these interactions span 182 individual medications.
We were not able to check the third ingredient, Bifidobacterium animalis lactis BL-04, because we don't hold interaction data for it. Use the medication checker on this page to look up your exact drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Acidophilus & Bifidus?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Acidophilus & Bifidus interact with 182 drugs. Click any drug to see the details.
2 of the 3 ingredients in Acidophilus & Bifidus interact with drugs. Each result below shows which ingredient is responsible. Bifidobacterium longum BL-5 Lactobacillus acidophilus LA-14
AmikacinAmikin, Arikayce
How Amikacin interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Amikacin interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Amoxicillin interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Amoxicillin Veterinary interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Amoxicillin, Clavulanate Potassium interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Amphotericin, Tetracycline interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Ampicillin interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Ampicillin, Sulbactam interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Avibactam Sodium, Ceftazidime interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Azithromycin interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Aztreonam interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Bacampicillin interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Bacitracin interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Benznidazole interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCapreomycinCapastat
How Capreomycin interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Capreomycin interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Capreomycin interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Carbenicillin Indanyl Sodium interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefaclor interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefadroxil interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefamandole interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefazolin interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefdinir interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefditoren Pivoxil interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefepime interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefiderocol Sulfate Tosylate interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefixime interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefixime interactionCefmetazoleZefazone
How Cefmetazole interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefmetazole interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefmetazole interactionCefonicidMonocid
How Cefonicid interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefonicid interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefonicid interactionCefoperazoneCefobid
How Cefoperazone interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefoperazone interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefoperazone interactionCefotaximeClaforan
How Cefotaxime interacts with Acidophilus & Bifidus — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefotaxime interactionLactobacillus Acidophilus La-14Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus La-14 + Cefotaxime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Acidophilus & Bifidus with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Bifidobacterium longum BL-5
Antibiotic Drugs
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.
Lactobacillus acidophilus LA-14
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Brand information
Manufacturer and brand details for Acidophilus & Bifidus, from the product label.
Lake Avenue Nutrition
See all Lake Avenue Nutrition products- Name
- Lake Avenue Nutrition
- Street Address
- 301 N. Lake ave., Ste. 600
- City
- Pasadena
- State
- CA
- ZipCode
- 91101
- Web Address
- lakeavenuenutrition.com
Acidophilus & Bifidus by Lake Avenue Nutrition: Common Questions
Does Acidophilus & Bifidus by Lake Avenue Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm on antibiotics?
What's this probiotic supposed to do?
Is it safe if I'm pregnant?
Can I use this while breastfeeding?
What side effects might I notice?
Is this safe if I'm seriously ill or have a weak immune system?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Acidophilus & Bifidus is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Acidophilus & Bifidus’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bifidobacterium Longum
Interacts with 182 drugsBifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...
Read the full Bifidobacterium Longum monograph → Herb & supplement monographLactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph →Sources & How We Checked
Acidophilus & Bifidus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 36 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bifidobacterium Longum 21 references
- Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
- Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
- Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
- US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
- Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
- Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
- Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
- Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
- Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
- Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
- Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
- Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
- Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
- Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed
See these in context on the Bifidobacterium Longum monograph →
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC