Interactions on record — worth a quick check against your medications. Based on 1 of 4 ingredients. Check your meds →
Dietary supplement

LiQ-10 Syrup Orange - Pineapple Flavor Ingredients & Drug Interactions

by Tishcon Corp.

LiQ-10 Syrup Orange - Pineapple Flavor label
See full label image
Liquid Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking LiQ-10 Syrup Orange - Pineapple Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

LiQ-10 Syrup Orange - Pineapple Flavor is a dietary supplement by Tishcon Corp. with 4 active ingredients. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coenzyme Q10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against LiQ-10 Syrup Orange - Pineapple Flavor by Tishcon Corp.

Ask about any prescription or over-the-counter medication and we check it for interactions with LiQ-10 Syrup Orange - Pineapple Flavor by Tishcon Corp. — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of LiQ-10 Syrup Orange - Pineapple Flavor by Tishcon Corp.

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

LiQ-10 Syrup contains 2 active ingredients: coenzyme Q10 (CoQ10) and fat. CoQ10 is a compound your cells use to produce energy and protect themselves from oxidative damage.

It occurs naturally in your body but can be depleted by certain medications (like statins) or by age. The inactive ingredients include a plain syrup base, purified water, medium-chain triglycerides, propylene glycol, orange and pineapple flavoring, and several other excipients like soy lecithin and sucralose.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Coenzyme Q10's overall clinical evidence instead.

Strong

Strong clinical evidence supports Coenzyme Q10 for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Coenzyme Q10 deficiency — rated "Likely Effective" (Natural Medicines).
  • On file: Migraine headache — rated "Possibly Effective" (Natural Medicines).
  • On file: Congestive heart failure (CHF) — rated "Possibly Effective" (Natural Medicines).
  • On file: Diabetic neuropathy — rated "Possibly Effective" (Natural Medicines).
  • On file: Fibromyalgia — rated "Possibly Effective" (Natural Medicines).

Coenzyme Q10 is likely effective for treating coenzyme Q10 deficiency itself. For other uses—fibromyalgia, migraine headache, congestive heart failure, and diabetic neuropathy—the evidence rates as possibly effective, meaning there is some clinical support but it's not yet definitive.

The data we hold does not establish effectiveness for any other conditions.

The evidence, ingredient by ingredient Coenzyme Q10

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Coenzyme Q10 is generally well tolerated in adults when used as directed. In clinical studies, no serious side effects have been reported.

Gastrointestinal side effects such as nausea, diarrhea, heartburn, and appetite suppression can occur, though these happen in less than 1% of users and are often minimized by dividing daily doses above 100 mg. Headache, dizziness, and insomnia have been reported.

Skin itching and rashes are rare. Regarding pregnancy, there is not enough reliable safety data, so it's best to avoid unless your doctor advises otherwise.

For breastfeeding, safety has not been well studied—talk with your doctor or pharmacist before using this product while nursing.

Side effects, ingredient by ingredient Coenzyme Q10

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Coenzyme Q10.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 198 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking LiQ-10 Syrup, check with your doctor or pharmacist if you take chemotherapy drugs like cyclophosphamide (alkylating agents), warfarin or other blood thinners, or blood pressure medications. Coenzyme Q10 may reduce how well chemotherapy works, interfere with warfarin's effectiveness, or lower blood pressure further.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

LiQ-10 Syrup may be worth considering if you have a documented coenzyme Q10 deficiency or are exploring it for migraine, heart failure, or nerve pain under your doctor's guidance. If you take warfarin, chemotherapy drugs, or blood pressure medications, you'll need to check with your doctor or pharmacist before starting this product.

Pregnancy and breastfeeding both require a conversation with your healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about LiQ-10 Syrup Orange - Pineapple Flavor, straight from the product label.

Brand Tishcon Corp.
Barcode (UPC) 014654391575
Net contents 16.9 fl. Oz.; 500 mL
Market status On market
Date entered into DSLD Jun 25, 2015
DSLD ID 46314
Product type Non-nutrient/non-botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for LiQ-10 Syrup Orange - Pineapple Flavor by Tishcon Corp., sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 tsp
Maximum serving Sizes:
1 tsp
UPC/BARCODE
014654391575
IngredientAmount% DV
Calories20 {Calories}--
Protein0 NP--
Fat1 Gram(s)2%
Carbohydrates4 Gram(s)1%
Coenzyme Q10100 mg--

Other ingredients: plain Syrup, purified Water, Medium Chain Triglycerides, Propylene Glycol, Orange flavor, Soy Lecithin, Pineapple flavor, Polysorbate 80, Citric Acid, Sucralose, Potassium Sorbate, Alpha-Tocopherol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Tamper Evident - DO NOT USE IF SAFETY SEAL UNDER CAP IS BROKEN OR MISSING.

WARNING: KEEP OUT OF REACH OF CHILDREN.

DIABETICS: THIS PRODUCT CONTAINS SUGAR (sucrose).

Contains soy.

Formula

DIABETICS: THIS PRODUCT CONTAINS SUGAR (sucrose).

Formulated with Li-Q-Sorb(R) Liposomal CoQ10

Contains soy.

Storage

Keep bottle tightly closed. Store in a cool, dry place at controlled room temperature 15(0)-30(0)C (59(0)-86(0)F). Do not refrigerate.

Brand IP Statement(s)

LiQ-10(R) and Li-Q-Sorb(R) are registered trademarks of Tishcon Corp.

Hydrosoluble(TM) is a trademark of Tishcon Corp.

General

9293L R0112

General Statements

Bioenhanced DOUBLE STRENGTH

Formulation

100% Hydrosoluble(TM) Vegetarian Formula

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Shake Well Before Using

Dosage: Take one (1) teaspoonful (5 mL) one to two times daily with meals, as a Coenzyme Q10 supplement or as recommended by your health care professional.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

LiQ-10 Syrup Orange - Pineapple Flavor by Tishcon Corp. label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

LiQ-10 Syrup Orange - Pineapple Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in LiQ-10 Syrup Orange - Pineapple Flavor by Tishcon Corp.

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 tsp Dosage formLiquid Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

0 NP per serving

Fat

1 Gram(s) per serving Form: Lecithin, Medium Chain Triglycerides

Carbohydrates

4 Gram(s) per serving Form: Sucrose

Coenzyme Q10

Interacts with
198 drugs
100 mg per serving Form: Ubidecarenone

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

Coenzyme Q10 monograph & interactions

Other (inactive) ingredients: Plain Syrup, Purified Water, Medium Chain Triglycerides, Propylene Glycol, Orange flavor, Soy Lecithin, Pineapple flavor, Polysorbate 80, Citric Acid, Sucralose, Potassium Sorbate, Alpha-Tocopherol. These complete the product’s ingredient list but are not active constituents.

Interaction report

LiQ-10 Syrup Orange - Pineapple Flavor by Tishcon Corp. Drug Interactions

Want to check YOUR meds against LiQ-10 Syrup Orange - Pineapple Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
198Drugs
26 Moderate 172 Minor

Ingredients driving the most interactions

Coenzyme Q10 198

Individual Drug Interactions

The ingredients in LiQ-10 Syrup Orange - Pineapple Flavor interact with 198 drugs. Click any drug to see the details.

1 of the 4 ingredients in LiQ-10 Syrup Orange - Pineapple Flavor interact with drugs. Each result below shows which ingredient is responsible. Coenzyme Q10

Each ingredient & the kinds of drugs it affects

For each ingredient in LiQ-10 Syrup Orange - Pineapple Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Coenzyme Q103 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
Coenzyme Q10 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for LiQ-10 Syrup Orange - Pineapple Flavor, from the product label.

Tishcon Corp.

See all Tishcon Corp. products
Phone Number
1-800-848-8442
Pharmacist Counseling Corner

LiQ-10 Syrup Orange - Pineapple Flavor by Tishcon Corp.: Common Questions

Does LiQ-10 Syrup Orange - Pineapple Flavor by Tishcon Corp. interact with any medications?
Yes. Based on its ingredients, LiQ-10 Syrup Orange - Pineapple Flavor has a known interaction with 198 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
LiQ-10 Syrup Orange - Pineapple Flavor contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is coenzyme Q10, and why is it in this product?
Coenzyme Q10 (CoQ10) is a natural compound your cells use to make energy and defend against damage. This product delivers CoQ10 in liquid form, which some people find easier to take than capsules. It's used for CoQ10 deficiency and has been studied for heart, migraine, and nerve pain support.
Can I take this if I'm on warfarin?
No, not without talking to your doctor first. Coenzyme Q10 may make warfarin less effective at preventing blood clots. A few cases have been reported where people's warfarin levels dropped when they started CoQ10. Your doctor needs to know before you add this product.
Will this lower my blood pressure?
Coenzyme Q10 may have additive effects if you're already taking blood pressure medications. Some research shows it can lower blood pressure on its own, though results are mixed. If you take blood pressure drugs, check with your doctor or pharmacist before starting.
Are there side effects I should know about?
Most people tolerate it well. Nausea, diarrhea, heartburn, and appetite suppression can occur but happen in fewer than 1% of users. Headache, dizziness, and insomnia have been reported. If you notice any of these, splitting your daily dose may help.
Is this safe during pregnancy or breastfeeding?
For pregnancy, there isn't enough safety data, so it's best to avoid unless your doctor says otherwise. For breastfeeding, safety hasn't been well studied either. Talk with your doctor or pharmacist before using this product in either situation.
Does this product work for heart failure?
The evidence for congestive heart failure rates as possibly effective—meaning there's some clinical support, but it's not yet definitive. Talk with your cardiologist about whether it makes sense for your individual situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if LiQ-10 Syrup Orange - Pineapple Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

LiQ-10 Syrup Orange - Pineapple Flavor label
Go deeper

The Full Monographs Behind LiQ-10 Syrup Orange - Pineapple Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph →
Sources

Sources & How We Checked

LiQ-10 Syrup Orange - Pineapple Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 40 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Coenzyme Q10 40 references
  1. Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
  2. Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
  3. Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
  4. Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
  5. Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
  6. Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
  7. Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
  8. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  9. Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
  10. Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
  11. Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
  12. The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
  13. Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
  14. Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
  15. Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
  16. Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
  17. Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
  18. Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
  19. Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
  20. Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
  21. Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
  22. Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
  23. Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
  24. Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
  25. Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
  26. Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
  27. Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
  28. Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
  29. Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
  30. Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
  31. Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
  32. Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
  33. Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
  34. Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
  35. Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
  36. Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
  37. Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. The effects of coenzyme Q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. PubMed
  38. Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: A systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2022;13:883251. PubMed
  39. Yaghini O, Hoseini N, Ghazavi MR, et al. A comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches in children: A randomized controlled trial. Adv Biomed Res 2022;11:43. PubMed
  40. Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed

See these in context on the Coenzyme Q10 monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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