Interactions on record — worth a quick check against your medications. Based on 6 of 9 ingredients. Check your meds →
Dietary supplement

AminH2O Blue Raspberry Ingredients & Drug Interactions

by Advanced Nutrition Systems

AminH2O Blue Raspberry label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking AminH2O Blue Raspberry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

AminH2O Blue Raspberry is a dietary supplement by Advanced Nutrition Systems with 9 active ingredients. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 331 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Citrulline DL Malate, Taurine, Coconut (Cocos nucifera) Water powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against AminH2O Blue Raspberry by Advanced Nutrition Systems

Ask about any prescription or over-the-counter medication and we check it for interactions with AminH2O Blue Raspberry by Advanced Nutrition Systems — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of AminH2O Blue Raspberry by Advanced Nutrition Systems

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 9 active ingredients.
  • “Branched-Chain Amino Acids” is listed as a grouped ingredient — the label gives one combined amount (4 Gram(s)) without saying how much of each component you get.
  • “Recover and Hydrate Blend” is a proprietary blend — the label gives one combined amount (4 Gram(s)) without saying how much of each component you get.

AminH2O Blue Raspberry contains nine active ingredients designed to support hydration, recovery, and muscle function. The formula includes three branched-chain amino acids—L-Leucine, L-Isoleucine, and L-Valine—plus L-Glutamine, all protein building blocks that play roles in muscle health and recovery after exercise or stress.

Taurine supports cardiovascular function, while L-Citrulline DL Malate may help with blood flow and athletic performance. Betaine Anhydrous supports cellular function and homocysteine metabolism.

Potassium helps with electrolyte balance and hydration, and Coconut Water Powder adds natural electrolytes and minerals. The inactive ingredients listed are typical excipients—citric acid, malic acid, natural and artificial flavors, sweeteners (sucralose and acesulfame potassium), thickeners (calcium silicate and silicon dioxide), and food coloring (FD&C Blue #1).

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Sickle cell disease — rated "Effective" (Glutamine) (Natural Medicines).
  • On file: Homocystinuria — rated "Effective" (Betaine Anhydrous) (Natural Medicines).
  • On file: HIV/AIDS-related wasting — rated "Possibly Effective" (Glutamine) (Natural Medicines).
  • On file: Critical illness (trauma) — rated "Possibly Effective" (Glutamine) (Natural Medicines).
  • On file: Postoperative recovery — rated "Possibly Effective" (Glutamine) (Natural Medicines).

The evidence for effectiveness varies by ingredient and use case. L-Glutamine is rated Effective for sickle cell disease and Possibly Effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness.

L-Citrulline is Possibly Effective for athletic performance but Possibly Ineffective for sarcopenia; evidence for heart failure, cardiovascular disease, and diabetes is not yet established. Betaine Anhydrous is Effective for homocystinuria and Possibly Effective for high homocysteine levels, but evidence for fatty liver disease (NASH), depression, and reflux is insufficient.

Taurine is Possibly Effective for congestive heart failure and hepatitis but Possibly Ineffective for weight loss. For coconut water powder, the evidence base is thin—ratings show insufficient data for diabetes, cholesterol, weight loss, and lichen planus.

The product's overall benefit depends on your specific reason for use; we recommend discussing your goals with your pharmacist.

The evidence, ingredient by ingredient Potassium Glutamine Taurine Betaine Anhydrous L-citrulline Coconut

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Glutamine is generally well tolerated in healthy adults but should be used only under medical supervision if you have kidney or liver disease. Common side effects include belching, bloating, constipation, nausea, and diarrhea; dizziness and headache have been reported in some cases.

Very rarely, mania or hypomania have occurred in people with bipolar disorder taking high doses. Taurine is generally well tolerated short-term, with common side effects being constipation, diarrhea, and indigestion.

Rare serious reactions include allergic hypersensitivity, especially in people with sulfite or sulfonamide allergies. Betaine can cause body odor, diarrhea, nausea, vomiting, and GI distress.

L-Citrulline may cause gastrointestinal discomfort and heartburn. Potassium at high levels can cause nausea, vomiting, abdominal pain, and in severe cases, dangerous heart rhythm changes.

Coconut can trigger allergic reactions including hives and, rarely, anaphylaxis in those with coconut sensitivity.

Side effects, ingredient by ingredient Potassium Glutamine Taurine Betaine Anhydrous L-citrulline Coconut

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 6 matched ingredients can interact with medications — Potassium, Glutamine, Taurine, L-citrulline, Coconut.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications; diabetes medications; lithium.
  • For scale: 331 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you use AminH2O Blue Raspberry, double-check these medication types: anticonvulsants (seizure drugs), antihypertensive drugs (blood pressure medications), lithium, potassium-sparing diuretics, ACE inhibitors and ARBs (blood pressure drugs), phosphodiesterase-5 inhibitors (erectile dysfunction drugs), and antidiabetes medications. Use the medication checker on this page to confirm none of yours are on the list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product is designed for active people seeking recovery and hydration support, especially athletes. However, if you take anticonvulsants, blood pressure medications, lithium, potassium-sparing diuretics, ACE inhibitors, ARBs, erectile dysfunction medications, or diabetes drugs, you need to check your exact medications against the tool on this page before starting.

People with kidney or liver disease should talk with their doctor first, as should anyone with a history of bipolar disorder or coconut allergies.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 21, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about AminH2O Blue Raspberry, straight from the product label.

Brand Advanced Nutrition Systems
Barcode (UPC) 814995020192
Net contents 10.74 oz.; 304.5 Gram(s)
Market status On market
Date entered into DSLD Sep 21, 2018
DSLD ID 180465
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for AminH2O Blue Raspberry by Advanced Nutrition Systems, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10.15 Gram(s)
Maximum serving Sizes:
10.15 Gram(s)
Servings per container
30
UPC/BARCODE
814995020192
IngredientAmount% DV
Total Carbohydrates1 Gram(s)1%
L-Glutamine0 NP--
L-Leucine0 NP--
L-Isoleucine0 NP--
Taurine0 NP--
L-Valine0 NP--
Betaine Anhydrous0 NP--
Branched-Chain Amino Acids4 Gram(s)--
Potassium90 mg3%
Recover and Hydrate Blend4 Gram(s)--
L-Citrulline DL Malate0 NP--
Coconut (Cocos nucifera) Water powder0 NP--

Other ingredients: Citric Acid, Natural and Artificial flavors, Calcium Silicate, Sucralose, Malic Acid, Silicon Dioxide, Acesulfame Potassium, FD&C Blue #1

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warning: Do not use if pregnant, nursing, or plan on becoming pregnant.

This product is intended for use by healthy adults over the age of 18. Do not use this product continuously for more than 8 weeks. Do not combine with alcohol. Not intended for use by those with a medical condition. Use only as directed. Do not exceed recommended daily intake.

Consult a physician or licensed qualified health care professional prior to use if you are pregnant, or nursing, or if you are taking medication, or if you have a medical condition, including, but not limited to, heart, liver, kidney, or thyroid disease, psychiatric or epileptic disorders, enlarged prostate, or glaucoma.

Discontinue 2 weeks prior to surgery or if you experience rapid heart beat, dizziness, severe headache or shortness of breath. Do not use if safety seal under cap is broken.

Keep out of the reach of children.

Contains: Tree Nut (Coconut)

Storage

Store in a cool, dry place.

General Statements

Please recycle.

Made in the USA Proudly made in the USA with carefully selected ingredients of international and domestic origin.

30 Servings

Strength Hydration Recovery

Naturally and Artificially Flavored

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General

Item ANS-122 1.1

Formula

3:1:1 Ratio BCAA + Hydration

AminH2O contains 4g of BCAAs designed to fuel recovery, replenish electrolytes and support muscle growth.

Contains: Tree Nut (Coconut)

Suggested/Recommended/Usage/Directions

This product can be taken before, during or after your workout to provide your body with the nutrients it needs to stay hydrated, promote endurance and build strength.

Suggested Use: As a dietary supplement, adults mix each serving (1 scoop) with 8 oz of water 20-30 minutes before, during, or immediately after your workout. Please read the entire label before use.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

AminH2O Blue Raspberry by Advanced Nutrition Systems label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

AminH2O Blue Raspberry label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in AminH2O Blue Raspberry by Advanced Nutrition Systems

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size10.15 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Branched-Chain Amino Acids

4 Gram(s) per serving
  • › L-Leucine
  • › L-Isoleucine
  • › L-Valine

Potassium

Interacts with
62 drugs
90 mg per serving Form: Potassium Phosphate

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Recover and Hydrate Blend

4 Gram(s) per serving

Other (inactive) ingredients: Citric Acid, Natural and Artificial flavors, Calcium Silicate, Sucralose, Malic Acid, Silicon Dioxide, Acesulfame Potassium, FD&C Blue #1. These complete the product’s ingredient list but are not active constituents.

Interaction report

AminH2O Blue Raspberry by Advanced Nutrition Systems Drug Interactions

Want to check YOUR meds against AminH2O Blue Raspberry?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
331Drugs
245 Moderate 86 Minor

Ingredients driving the most interactions

L-Citrulline DL Malate 178
Taurine 173
Coconut (Cocos nucifera) Water powder 86
Potassium 62
L-Glutamine 50

Individual Drug Interactions

The ingredients in AminH2O Blue Raspberry interact with 331 drugs. Click any drug to see the details.

5 of the 9 ingredients in AminH2O Blue Raspberry interact with drugs. Each result below shows which ingredient is responsible. L-Citrulline DL Malate Taurine Coconut (Cocos nucifera) Water powder Potassium L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in AminH2O Blue Raspberry with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Citrulline DL Malate2 drug types · 178 drugs

Antihypertensive Drugs

Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.

Likelihood Possible Evidence B
Phosphodiesterase-5 Inhibitors

Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
L-Citrulline DL Malate full monograph & interactions

Taurine2 drug types · 173 drugs

Antihypertensive Drugs

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Some clinical evidence suggests that taurine can reduce both systolic and diastolic blood pressure.

Likelihood Probable Evidence D
Lithium

Theoretically, taurine might reduce excretion and increase plasma levels of lithium.
Taurine is thought to have diuretic properties, which might reduce the excretion of lithium.

Likelihood Probable Evidence D
Taurine full monograph & interactions

Coconut (Cocos nucifera) Water powder1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that coconut milk might increase insulin levels and/or decrease blood glucose levels.

Likelihood Unlikely Evidence D
Coconut (Cocos nucifera) Water powder full monograph & interactions

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for AminH2O Blue Raspberry, from the product label.

Advanced Nutrition Systems

See all Advanced Nutrition Systems products
Name
Advanced Nutrition LLC
Street Address
221 S. Cherokee St.
City
Denver
State
CO
ZipCode
80223
Web Address
www.advanced247.com
Pharmacist Counseling Corner

AminH2O Blue Raspberry by Advanced Nutrition Systems: Common Questions

Does AminH2O Blue Raspberry by Advanced Nutrition Systems interact with any medications?
Yes. Based on its ingredients, AminH2O Blue Raspberry has a known interaction with 331 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
AminH2O Blue Raspberry contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this product safe during pregnancy?
L-Glutamine and Taurine are rated Likely Safe in pregnancy, but L-Citrulline has insufficient safety data, and the facts advise against supplemental doses during pregnancy. Betaine's pregnancy safety isn't on file. Talk with your doctor or pharmacist before using this product if you're pregnant, so they can weigh the ingredients for your situation.
Can I use this while breastfeeding?
L-Glutamine, Taurine, and Potassium are rated Likely Safe while nursing, but L-Citrulline's safety is unknown and should be avoided during breastfeeding. Betaine's breastfeeding safety isn't established. Check with your pharmacist or doctor before use if you're nursing.
What's L-Glutamine supposed to do?
L-Glutamine is an amino acid that's been shown to be effective for sickle cell disease and possibly helpful for recovery after surgery, critical illness, and HIV/AIDS-related muscle wasting. It plays a role in muscle repair and immune function.
Will this help me with my workout recovery?
The formula includes several ingredients tied to recovery: L-Glutamine is possibly effective for postoperative recovery, L-Citrulline is possibly effective for athletic performance, and taurine supports heart and muscle function. However, individual results depend on your training, diet, and overall health—talk with your pharmacist about whether this fits your routine.
What are the most common side effects?
Gastrointestinal side effects are most common: bloating, gas, diarrhea, constipation, nausea, and stomach discomfort. These typically occur because of the amino acids and electrolytes in the formula. Start with a smaller amount to see how your stomach handles it.
Do I need to worry about the potassium in this product?
Potassium is included for electrolyte balance, but it's a concern if you take potassium-sparing diuretics, ACE inhibitors, ARBs, or have kidney disease. High potassium levels can be dangerous. Use the medication checker to confirm your drugs, and ask your pharmacist whether the potassium dose in this product is safe for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if AminH2O Blue Raspberry is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

AminH2O Blue Raspberry label
Go deeper

The Full Monographs Behind AminH2O Blue Raspberry’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph → Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Taurine

Interacts with 173 drugs

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements, and short-term use appears generally sa...

Read the full Taurine monograph → Herb & supplement monograph

Betaine Anhydrous

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and as a prescription medicine for a rare gen...

Read the full Betaine Anhydrous monograph → Herb & supplement monograph

L-citrulline

Interacts with 178 drugs

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. It is popular for exercise performance an...

Read the full L-citrulline monograph → Herb & supplement monograph

Coconut

Interacts with 86 drugs

Coconut is a nutritious tropical food enjoyed as oil, water, milk, and flesh, and it is generally safe to eat in normal food amounts. While some uses (like skin moisturizing and hydration) h...

Read the full Coconut monograph →
Sources

Sources & How We Checked

AminH2O Blue Raspberry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 73 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Taurine 21 references
  1. Ahmad S, Robertson HT, Golper TA, et al. Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects. Kidney Int 1990;38:912-8. PubMed
  2. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  3. Obermann M, Schorn CF, Mummel P, et al. Taurine induced toxic encephalopathy? Clin Neurol Neurosurg 2006;108:812-3. PubMed
  4. Bichler, A., Swenson, A., and Harris, M. A. A combination of caffeine and taurine has no effect on short term memory but induces changes in heart rate and mean arterial blood pressure. Amino Acids 2006;31(4):471-476. PubMed
  5. Iyadurai, S. J. and Chung, S. S. New-onset seizures in adults: possible association with consumption of popular energy drinks. Epilepsy Behav 2007;10(3):504-508. PubMed
  6. Berger, A. J. and Alford, K. Cardiac arrest in a young man following excess consumption of caffeinated "energy drinks". Med J Aust. 1-5-2009;190(1):41-43. PubMed
  7. Worthley, M. I., Prabhu, A., De, Sciscio P., Schultz, C., Sanders, P., and Willoughby, S. R. Detrimental effects of energy drink consumption on platelet and endothelial function. Am J Med 2010;123(2):184-187. PubMed
  8. Morchon, Simon D. and Perez Castrillon, J. L. [Hypoglycemia by intake of taurine]. Rev.Clin Esp. 2010;210(1):49.
  9. Livshits, Z., Hoffman, R. S., Hymes, K. B., and Nelson, L. S. If vitamins could kill: massive hemolysis following naturopathic vitamin infusion. J Med Toxicol. 2011;7(3):224-226. PubMed
  10. Schoffl, I., Kothmann, J. F., Schoffl, V., Rupprecht, H. D., and Rupprecht, T. "Vodka energy": too much for the adolescent nephron? Pediatrics 2011;128(1):e227-e231. PubMed
  11. Calabro, R. S., Italiano, D., Gervasi, G., and Bramanti, P. Single tonic-clonic seizure after energy drink abuse. Epilepsy Behav 2012;23(3):384-385. PubMed
  12. Fujita, T., Ando, K., Noda, H., Ito, Y., and Sato, Y. Effects of increased adrenomedullary activity and taurine in young patients with borderline hypertension. Circulation 1987;75(3):525-532. PubMed
  13. Darling, P. B., Lepage, G., Leroy, C., Masson, P., and Roy, C. C. Effect of taurine supplements on fat absorption in cystic fibrosis. Pediatr Res 1985;19(6):578-582. PubMed
  14. Fukuyama, Y. and Ochiai, Y. Therapeutic trial by taurine for intractable childhood epilepsies. Brain Dev. 1982;4(1):63-69. PubMed
  15. Franconi, F., Bennardini, F., Mattana, A., Miceli, M., Ciuti, M., Mian, M., Gironi, A., Anichini, R., and Seghieri, G. Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation. Am.J. DOI
  16. Stohs SJ, Miller M. A case study involving allergic reactions to sulfur-containing compounds including, sulfite, taurine, acesulfame potassium and sulfonamides. Food Chem Toxicol. 2014 Jan;63:240-3. PubMed
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Betaine Anhydrous 11 references
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  2. Abdelmalek MF, Angulo P, Jorgensen RA, et al. Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Am J Gastroenterol 2001;96:2711-7.. PubMed
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Potassium 12 references
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  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
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  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
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  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

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L-citrulline 8 references
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  2. Schwedhelm E, Maas R, Freese R, et al. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol 2008;65:51-9. PubMed
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  8. Xu Z, Liu C, Liu S, Zhou Z. Comparison of efficacy and safety of daily oral L-arginine and PDE5Is alone or combination in treating erectile dysfunction: A systematic review and meta-analysis of randomised controlled trials. Andrologia. 2021:e14007. PubMed

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Coconut 10 references
  1. Teuber SS, Peterson WR. Systemic allergic reaction to coconut (Cocos nucifera) in 2 subjects with hypersensitivity to tree nut and demonstration of cross-reactivity to legumin-like seed storage proteins: new coconut and walnut food allergens. J Allergy Cl PubMed
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  5. Cifuentes L, Mistrello G, Amato S, et al. Identification of cross-reactivity between buckwheat and coconut. Ann Allergy Asthma Immunol. 2015;115(6):530-2. PubMed
  6. Michavila Gomez A, Amat Bou M, Gonzalez Cortés MV, Segura Navas L, Moreno Palanques MA, Bartolomé B. Coconut anaphylaxis: Case report and review. Allergol Immunopathol (Madr). 2015;43(2):219-20. PubMed
  7. 21CFR170.3. U.S. Food and Drug Administration Department of Health and Human Services. Updated April 1, 2017. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=170.3
  8. Alatawi KA, Alshubaily FA. Coconut products alleviate hyperglycaemic, hyperlipidimic and nephropathy indices in streptozotocin-induced diabetic wistar rats. Saudi J Biol Sci. 2021;28(8):4224-4231. PubMed
  9. Kruse L, Lor J, Yousif R, Pongracic JA, Fishbein AB. Coconut allergy: Characteristics of reactions and diagnostic predictors in a pediatric tertiary care center. Ann Allergy Asthma Immunol 2021;126(5):562-568.
  10. Pathmanandavel K, Kaur N, Joshi P, Ford LS. Anaphylaxis and allergy to coconut: An Australian pediatric case series. J Allergy Clin Immunol Pract 2020;8(10):3657-3659. PubMed

See these in context on the Coconut monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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