Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

ArgiFlow Lemon Flavor Ingredients & Drug Interactions

by Ajinomoto

ArgiFlow Lemon Flavor label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking ArgiFlow Lemon Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

ArgiFlow Lemon Flavor is a dietary supplement by Ajinomoto with 4 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 434 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Arginine, Sodium, Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against ArgiFlow Lemon Flavor by Ajinomoto

Ask about any prescription or over-the-counter medication and we check it for interactions with ArgiFlow Lemon Flavor by Ajinomoto — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of ArgiFlow Lemon Flavor by Ajinomoto

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 2 of its 3 active ingredients.

ArgiFlow Lemon Flavor contains three active ingredients: sodium (the mineral that helps regulate body fluid and nerve function), potassium (another mineral critical for heart rhythm and muscle function), and L-arginine (an amino acid your body uses to make nitric oxide, a compound that relaxes blood vessels). The product also contains several inactive ingredients—sweeteners, flavor compounds, and a carbohydrate (Cluster Dextrin)—that serve as fillers, binders, and taste enhancers.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Cystic fibrosis — rated "Likely Effective" (Sodium) (Natural Medicines).
  • On file: Amphotericin B nephrotoxicity — rated "Possibly Effective" (Sodium) (Natural Medicines).

The product facts we hold do not include effectiveness ratings for potassium or L-arginine in this formulation. Sodium has established uses in cystic fibrosis (where it's likely effective) and possibly helps reduce kidney damage from the antibiotic amphotericin B, though the evidence for that use is limited.

We don't have reliable evidence that sodium helps with bipolar disorder or heart failure.

The evidence, ingredient by ingredient Sodium Potassium L-arginine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sodium is well tolerated in normal dietary amounts, but too much is linked to high blood pressure and heart strain; avoid supplements or very high intake without medical guidance. Potassium from food is fine, but supplements can cause dangerously high blood levels in some people, especially those with kidney disease.

L-arginine is often well tolerated in the short term, but it can lower blood pressure and may not be safe for everyone—use only under medical supervision. The most common side effects from potassium are stomach pain, diarrhea, nausea, and gas.

L-arginine may cause abdominal pain, bloating, nausea, diarrhea, headache, or flushing. Serious but rare effects include sodium buildup causing worsening heart disease or kidney problems, and high potassium causing irregular heartbeat or cardiac arrest.

Side effects, ingredient by ingredient Sodium Potassium L-arginine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Potassium, L-arginine, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 434 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check these medication types before using this product: blood pressure medications (antihypertensives), potassium-sparing diuretics, ACE inhibitors, angiotensin receptor blockers (ARBs), corticosteroids, the mood stabilizer lithium, blood thinners and antiplatelet drugs, diabetes medications, and the HIV drug didanosine. All carry Moderate-severity interactions with one or more of the product's ingredients.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

ArgiFlow Lemon Flavor is a three-ingredient powder that carries significant interaction risks, especially if you take blood pressure medications, heart drugs, potassium-sparing diuretics, lithium, blood thinners, or diabetes medications. Check your exact medications with the tool on this page before starting.

If you take any prescription medications, talk with your pharmacist or doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ArgiFlow Lemon Flavor, straight from the product label.

Brand Ajinomoto
Barcode (UPC) 071757606340
Net contents 30 Packet(s); 15 Oz(s); 426 Gram(s)
Market status On market
Date entered into DSLD Dec 22, 2017
DSLD ID 81329
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ArgiFlow Lemon Flavor by Ajinomoto, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
14.2 Gram(s)
Maximum serving Sizes:
14.2 Gram(s)
Servings per container
30
UPC/BARCODE
071757606340
IngredientAmount% DV
Calories30 Calorie(s)--
Total Carbohydrates7 Gram(s)2%
Sugar0 Gram(s)--
Sodium0 mg--
Potassium150 mg4%
Total Fat0 Gram(s)--
L-Arginine5000 mg--

Other ingredients: Erythritol, Citric Acid, Natural flavor, Malic Acid, Cluster Dextrin, Potassium Citrate, Rebaudioside A, Fruit and Vegetable Juice

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Patented Ferment-A-Pure Technology 100% All natural For more than a century, Ajinomoto Co., Inc. has pioneered the development of new and innovated technologies used to manufacture and purify pharmaceutical grade amino acids.

Industry leading purification processes allow quicker absorption, faster bio-availability, proven consistency and unrivaled efficacy. Ajinomoto Co., Inc. is the global leader in production, sales and research of amino acids used for medical, pharmaceutical, nutraceutical, sport, nutrition and health industries.

Environmental sustainability

100% vegetable fermentation

Ajinomoto Co., Inc. has been the world's leading producer of amino acids for nearly 100 years and has been producing pharmaceutical grade amino acids since 1956. Our amino acids are trusted for clinical research and used by medical doctors, hospitals, professional and Olympic athletes and professional health care facilities worldwide.

Supports healthy blood pressure and blood flow already within a normal range Promotes healthy levels of growth hormone Promotes the urea cycle in the removal of toxic ammonia from the body

Low calorie single serve packets

Pharmaceutical grade L-arginine powder

30 x 0.51 oz. (14.2g) packets

Brand IP Statement(s)

AjiPure amino acids are fermented using only natural plant-based carbohydrates as raw materials.

AjiPure amino acids stem from over 100 years of clinical and scientific research, yielding unsurpassed quality and purity.

ArgiFlow Lemon supports healthy blood pressure and blood flow already within a normal range, promotes healthy levels of growth hormone, and promotes the urea cycle in the removal of toxic ammonia from the body.

Pure & Naturally Flavored: ArgiFlow Lemon uses real fruit and vegetable blends to offer a delicious combination of natural flavor, natural color and natural sweetness in an easy to use powder.

AjiPure Amino Acids

Made by Ajinomoto

AjiPure is a registered trademark of Ajinomoto Co., Inc. ArgiFlow is a registered trademark of Ajinomoto Co., Inc.

Formula

AjiPure amino acids are fermented using only natural plant-based carbohydrates as raw materials.

OU

ArgiFlow Advantage: Unlike conventional L-arginine which may often be diluted with fillers or made from low grade or impure ingredients which can reduce efficacy, ArgiFlow Lemon contains the world's highest purity, fermented, plant-source L-arginine available on the global market.

Formulation

Ajinomoto Co., Inc. never uses raw materials of animal origin in any production process.

Certified Vegan Vegan.org

Non-GMO

No artificial additives/fillers

Certified drug free

Zero sugar

No gluten, no yeast, no corn, no wheat, no dairy, no fish, no artificial colors, no preservatives.

Seals/Symbols

Certified Vegan Vegan.org

Gluten free

Non-GMO

Packaged in the USA

No artificial additives/fillers

cGMP GMP compliant

BSCG Banned Substances Control Group The gold standard www.BSCG.org Certified drug free

OU

Laboratory tested

Suggested/Recommended/Usage/Directions

Try taking ArgiFlow Lemon at bed time to help promote healthy levels of growth hormone.

ArgiFlow Stacks Up: Try stacking ArgiFlow Lemon with other preferred supplements and various powder preparations for an even more powerful boost. Try stacking ArgiFlow Lemon at bed time to help promote healthy levels of growth hormone.

For optimal taste, simply mix one packet of ArgiFlow Lemon powder with cold water and consume completely while beverage is still cold. Stir, Shake Or Blend: ArgiFlow Lemon is optimized for superior dissolvability and superior bioavailability. ArgiFlow Lemon may be mixed with cold water by stirring with a spoon, by shaking in a shaker or by blending in a conventional blender.

Directions & Suggested Use: Take as directed by a healthcare professional, or as a dietary supplement, mix one packet with 20 fl. oz. of cold water. Stir, shake or blend well for 20-30 seconds or until ArgiFlow Lemon powder is completely dissolved. For a sweeter taste use less water and for a lighter taste add more water. To aid in cardiovascular support, consume one packet in the morning. To support stamina during training, consume one or two packets 30 minutes prior to physical activity. For optimal use, consume on an empty stomach.

FDA Statement of Identity

Amino Acid Supplement

Storage

Store in a cool dry place.

Precautions

Keep out of reach of children.

Tamper Resistant: Do not use if seal is broken.

Warning: Consult your physician prior to consuming this product if you are pregnant, taking medication, or have any medical condition.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

ArgiFlow Lemon Flavor by Ajinomoto label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

ArgiFlow Lemon Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in ArgiFlow Lemon Flavor by Ajinomoto

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size14.2 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

0 Gram(s) per serving

Sodium

Interacts with
205 drugs
0 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Potassium

Interacts with
62 drugs
150 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

L-Arginine

Interacts with
403 drugs
5000 mg per serving

L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen. It is popularly used for bl...

L-Arginine monograph & interactions

Other (inactive) ingredients: Erythritol, Citric Acid, Natural flavor, Malic Acid, Cluster Dextrin, Potassium Citrate, Rebaudioside A, Fruit and Vegetable Juice. These complete the product’s ingredient list but are not active constituents.

Interaction report

ArgiFlow Lemon Flavor by Ajinomoto Drug Interactions

Want to check YOUR meds against ArgiFlow Lemon Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
434Drugs
426 Moderate 8 Minor

Ingredients driving the most interactions

L-Arginine 403
Sodium 205
Potassium 62

Individual Drug Interactions

The ingredients in ArgiFlow Lemon Flavor interact with 434 drugs. Click any drug to see the details.

3 of the 4 ingredients in ArgiFlow Lemon Flavor interact with drugs. Each result below shows which ingredient is responsible. L-Arginine Sodium Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in ArgiFlow Lemon Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Arginine9 drug types · 403 drugs

Ace Inhibitors (Aceis)

Theoretically, concomitant use of L-arginine and ACE inhibitors may increase the risk for hypotension and hyperkalemia.
Combining L-arginine with some antihypertensive drugs, especially ACE inhibitors, seems to have additive vasodilating and blood pressure-lowering effects. Furthermore, ACE inhibitors can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ACE inhibitors with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Angiotensin Receptor Blockers (Arbs)

Theoretically, concomitant use of L-arginine and ARBs may increase the risk of hypotension and hyperkalemia.
L-arginine increases nitric oxide, which causes vasodilation. Combining L-arginine with ARBs seems to increase L-arginine-induced vasodilation. Furthermore, ARBs can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ARBs with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of L-arginine with anticoagulant and antiplatelet drugs might have additive effects and increase the risk of bleeding.
Preliminary research suggests that L-arginine infusions reduce platelet aggregation in humans. The clinical significance of this effect is unclear.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of L-arginine might have additive effects with antidiabetes drugs.
Preliminary clinical research shows that L-arginine decreases blood glucose levels in patients with type 2 diabetes.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of L-arginine and antihypertensive drugs may increase the risk of hypotension.
L-arginine increases nitric oxide, which causes vasodilation. Clinical evidence shows that L-arginine can reduce blood pressure in some individuals with hypertension. Furthermore, combining L-arginine with some antihypertensive drugs seems to have additive vasodilating and blood pressure-lowering effects.

Likelihood Probable Evidence D
Isoproterenol (Isuprel)

Theoretically, concurrent use of isoproterenol and L-arginine might result in additive effects and hypotension.
Preliminary clinical evidence suggests that L-arginine enhances isoproterenol-induced vasodilation in patients with essential hypertension or a family history of essential hypertension.

Likelihood Probable Evidence D
Potassium-Sparing Diuretics

Theoretically concomitant use of potassium-sparing diuretics with L-arginine may increases the risk of hyperkalemia.
Potassium-sparing diuretics can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients.

Likelihood Possible Evidence D
Sildenafil (Viagra)

Theoretically, concurrent use of sildenafil and L-arginine might increase the risk for hypotension.
In vivo, concurrent use of L-arginine and sildenafil has resulted in increased vasodilation. Theoretically, concurrent use might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
Testosterone

Theoretically, concomitant use of L-arginine and testosterone might have additive effects.
In clinical research, L-arginine increases the level of testosterone in male patients with erectile dysfunction. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
L-Arginine full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for ArgiFlow Lemon Flavor, from the product label.

Ajinomoto

See all Ajinomoto products
Name
Ajinomoto North America, Inc.
Street Address
4020 Ajinomoto Dr.
City
Raleigh
State
NC
ZipCode
27610
Phone Number
(855) 254-7873
Web Address
www.AJIPURE.com
Pharmacist Counseling Corner

ArgiFlow Lemon Flavor by Ajinomoto: Common Questions

Does ArgiFlow Lemon Flavor by Ajinomoto interact with any medications?
Yes. Based on its ingredients, ArgiFlow Lemon Flavor has a known interaction with 434 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
ArgiFlow Lemon Flavor contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is ArgiFlow safe during pregnancy?
The data on file shows sodium is listed as likely safe, but potassium is listed as possibly unsafe in pregnancy. L-arginine is rated possibly safe during pregnancy. Because the product contains ingredients with conflicting safety ratings, talk with your doctor or pharmacist before using it while pregnant.
Can I take this while breastfeeding?
Sodium is likely safe during breastfeeding, and potassium is listed as likely safe. We don't have lactation safety data for L-arginine on file. Because of the mixed information, check with your pharmacist or doctor before using this product while nursing.
What is L-arginine supposed to do?
L-arginine is an amino acid your body uses to make nitric oxide, which relaxes blood vessels and improves blood flow. The product facts don't include evidence ratings for L-arginine's effectiveness in this formulation, so we can't tell you what it's intended to treat.
Will this product raise my blood pressure?
The sodium in this product could theoretically reduce how well your blood pressure medications work, potentially leading to higher blood pressure. On the other hand, L-arginine may lower blood pressure in some people. The net effect depends on your individual body and medications—talk with your pharmacist.
What are the most common side effects?
From potassium: stomach pain, diarrhea, nausea, and gas. From L-arginine: abdominal pain, bloating, nausea, diarrhea, headache, or flushing. Sodium in normal amounts has no typical side effects, but too much is associated with high blood pressure and heart strain over time.
Is this product safe if I have kidney disease?
This product contains potassium and sodium—both of which require careful medical management in kidney disease because your kidneys regulate these minerals. Do not use this without direct guidance from your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ArgiFlow Lemon Flavor label
Go deeper

The Full Monographs Behind ArgiFlow Lemon Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph → Herb & supplement monograph

L-arginine

Interacts with 403 drugs

L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen. It is popularly used for blood pressure, erectile dysfunction, and...

Read the full L-arginine monograph →
Sources

Sources & How We Checked

ArgiFlow Lemon Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 116 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
  7. Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
  8. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
  9. Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
  10. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
  11. D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
  12. Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
  13. Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
  14. Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
  15. Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
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See these in context on the Sodium monograph →

Potassium 12 references
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See these in context on the L-arginine monograph →

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