Ashwagandha Ingredients & Drug Interactions
by Sun Potion
What is this page for?
First and foremost: checking Ashwagandha against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Ashwagandha is a dietary supplement by Sun Potion with 1 active ingredient. Its ingredients are commonly taken for stress and anxiety, sleep problems, fatigue and low energy.Based on those ingredients, 1,372 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ashwagandha Root Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Ashwagandha by Sun Potion
Ask about any prescription or over-the-counter medication and we check it for interactions with Ashwagandha by Sun Potion — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Ashwagandha by Sun Potion
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Sun Potion Ashwagandha Powder contains one active ingredient: Ashwagandha Root Extract. There are no other inactive ingredients listed.
Ashwagandha is an herb traditionally used to help with stress, anxiety, sleep, and overall resilience during demanding times.
Does it work?
Moderate evidence
The evidence shows ashwagandha is possibly effective for insomnia, anxiety, stress, and generalized anxiety disorder (GAD). For bipolar disorder, the evidence we have isn't reliable enough to rate it one way or the other.
How safe is it?
Well-documented data
Ashwagandha is generally well tolerated short-term in healthy adults, though long-term safety data are limited. The most common side effects—when they do occur—are diarrhea, nausea, upset stomach, or vomiting, but these don't typically happen at standard doses.
Rare but serious side effects include liver problems ranging from hepatitis to liver failure, and there's one case report of reversible brain blood vessel constriction with bleeding. During pregnancy, ashwagandha is traditionally thought to risk miscarriage and is rated likely unsafe—avoid it.
While breastfeeding, there isn't enough safety information, so avoid it then too.
Meds to double-check
Moderate interaction found
Before you take this ashwagandha, double-check with your pharmacist if you're on any immune-suppressing medications, blood pressure drugs, sedatives or benzodiazepines, diabetes medications, thyroid hormones, or drugs that can affect the liver. These are the main categories where ashwagandha can interfere.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you're dealing with stress, anxiety, or sleep trouble and don't take medications that interact with ashwagandha, this may be worth trying. If you take a blood pressure drug, diabetes drug, sedative, benzodiazepine, thyroid hormone, an immunosuppressant, or anything that stresses your liver, talk to your pharmacist before adding this.
Don't use during pregnancy or while breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Ashwagandha, straight from the product label.
| Brand | Sun Potion |
|---|---|
| Barcode (UPC) | 850001146029 |
| Net contents | 3.9 Ounce(s); 111 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Mar 22, 2024 |
| DSLD ID | 307986 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Ashwagandha by Sun Potion, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Ashwagandha Root Extract | 1.25 Gram(s) | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Thank you for being here This is an amazing time on the planet. Participate in the shift. Experience transformational foods with Sun Potion! We want you to feel amazing. For daily alchemy + recipes Find us @sunpotion #sunpotion We invite your to reuse this glass jar. Thank you.
In joy!
Formulation
Wildcrafted Ayurvedic adaptogen Cold water extract
This anti-oxidant rich, powdered root extract may support: Strong immune system Sense of vigor + resilience Stress relief Hormonal balance Harmonize mind, body, & spirit
Formula
Ashwagandha Root
Indian Ginseng
Precautions
Keep out of reach of children.
Consult your healthcare practitioner before use if pregnant.
Suggested/Recommended/Usage/Directions
These are powerful foods. Consume in small, regular doses over a lifetime.
Invitations for use Add 1/2 teaspoon (2 grams) to warm water or tea! Excellent addition to milk potions, elixirs, smoothies, raw treats, busy schedules.
FDA Disclaimer Statement
These statements have not been approved by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Ashwagandha by Sun Potion label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Ashwagandha by Sun Potion
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1.25 Gram(s) Dosage formPowder Servings per container88 Amounts shown are per serving.
Ashwagandha Root Extract
Interacts with1,372 drugs
Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evid...
Ashwagandha Root Extract monograph & interactionsAshwagandha by Sun Potion Drug Interactions
HelloPharmacist Interaction Report
Ashwagandha Root Extract by Sun Potion has documented interactions with a substantial number of medications.
The most serious concern involves drugs that suppress the immune system (immunosuppressants): ashwagandha appears to boost immune function, which could work against these medications and reduce their intended effect.
Read the full breakdown — every affected drug type, severity by severity
Mother serious interactions are Moderate in severity. CNS depressants—including benzodiazepines, barbiturates, and other sedatives—may have their drowsy and calming effects amplified.
Blood pressure medications (antihypertensives) carry a risk of blood pressure dropping too low. Diabetes drugs may increase the chance of low blood sugar (hypoglycemia).
Thyroid hormones could have their effects and side effects strengthened. And ashwagandha paired with drugs that stress the liver may raise the risk of liver damage.
One more Moderate interaction: ashwagandha might lower levels of certain drugs your liver processes through the CYP1A2 enzyme system, though this is Minor in severity. Altogether, these interactions span 1,351 individual medications.
Please check your exact medications with the tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Ashwagandha?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Ashwagandha interact with 1,372 drugs. Click any drug to see the details.
1 of the 1 ingredient in Ashwagandha interact with drugs. Each result below shows which ingredient is responsible. Ashwagandha Root Extract
AlogliptinNesina
How Alogliptin interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha Root Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Ashwagandha Root Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractAntidiabetes Drugs, Hepatotoxic Drugs +1 Moderate
Interaction Summary
Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Ashwagandha Root Extract + Alogliptin, Pioglitazone interactionAlprazolamNiravam, Xanax
How Alprazolam interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractBenzodiazepines, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
Read the full Ashwagandha Root Extract + Alprazolam interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Read the full Ashwagandha Root Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs +1 Moderate
Interaction Summary
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Ashwagandha Root Extract + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Ashwagandha Root Extract + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Ashwagandha Root Extract + Amiloride, Hydrochlorothiazide interactionAminoglutethimideCytadren
How Aminoglutethimide interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Read the full Ashwagandha Root Extract + Aminoglutethimide interactionAminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Read the full Ashwagandha Root Extract + Aminophylline, Amobarbital, Ephedrine interactionAminosalicylic AcidPaser
How Aminosalicylic Acid interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha Root Extract + Aminosalicylic Acid interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha Root Extract + Amiodarone interactionAmitriptylineElavil
How Amitriptyline interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Ashwagandha Root Extract + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractSerotonergic Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +3 Moderate
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Ashwagandha Root Extract + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractCns Depressants, Serotonergic Drugs +2 Moderate
Interaction Summary
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Read the full Ashwagandha Root Extract + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Ashwagandha Root Extract + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Ashwagandha Root Extract + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Ashwagandha Root Extract + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Ashwagandha Root Extract + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Ashwagandha Root Extract + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Ashwagandha Root Extract + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Ashwagandha Root Extract + Ammonium Chloride interactionAmobarbitalAmytal
How Amobarbital interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Read the full Ashwagandha Root Extract + Amobarbital interactionAmobarbital, Ephedrine SulfateEphedrine & Amytal
How Amobarbital, Ephedrine Sulfate interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Read the full Ashwagandha Root Extract + Amobarbital, Ephedrine Sulfate interactionAmobarbital, SecobarbitalTuinal
How Amobarbital, Secobarbital interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Read the full Ashwagandha Root Extract + Amobarbital, Secobarbital interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha Root Extract + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha Root Extract + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha Root Extract + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Ashwagandha Root Extract + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Ashwagandha — through 1 ingredient. Tap an ingredient for the detail:
Ashwagandha Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha Root Extract + Amphotericin, Tetracycline interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Ashwagandha with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Ashwagandha Root Extract
Antidiabetes Drugs
Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.
Antihypertensive Drugs
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Benzodiazepines
Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.
Cns Depressants
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.
Hepatotoxic Drugs
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.
Immunosuppressants
Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.
Thyroid Hormone
Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.
Serotonergic Drugs
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]
Brand information
Manufacturer and brand details for Ashwagandha, from the product label.
Sun Potion
See all Sun Potion products- Name
- Sun Potion, LLC Transformational Foods
- Street Address
- 430 E. Gutierrez Street
- City
- Santa Barbara
- State
- CA
- Phone Number
- 866.676.8466
- Web Address
- www.SunPotion.com
Ashwagandha by Sun Potion: Common Questions
Does Ashwagandha by Sun Potion interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take ashwagandha while I'm pregnant?
Is it safe to use while breastfeeding?
What are the most common side effects?
How long does it take to work for anxiety or sleep?
Can ashwagandha make me drowsy?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Ashwagandha is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Ashwagandha’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Ashwagandha's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 32 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Ashwagandha 32 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Upton R, ed. Ashwagandha Root (Withania somnifera): Analytical, quality control, and therapuetic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia 2000:1-25.
- Davis L, Kuttan G. Effect of Withania somnifera on cyclophosphamide-induced urotoxicity. Cancer Lett 2000;148:9-17. PubMed
- Davis L, Kuttan G. Suppressive effect of cyclophosphamide-induced toxicity by Withania somnifera extract in mice. J Ethnopharmacol 1998;62:209-14. PubMed
- Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev 2000;5:334-46. DOI
- Andallu B, Radhika B. Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root. Indian J Exp Biol 2000;38:607-9.
- Kulkarni RR, Patki PS, Jog VP, et al. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol 1991;33:91-5. PubMed
- Ahumada F, Aspee F, Wikman G, Hancke J. Withania somnifera exract. Its effects on arterial blood pressure in anaesthetized dogs. Phytother Res 1991;5:111-14.
- Panda S, Kar A. Withania somnifera and Bauhinia purpurea in the regulation of circulating thyroid hormone concentrations in female mice. J Ethnopharmacol 1999;67:233-39. PubMed
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