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Dietary supplement

Astaxanthin Softgels 12 mg Ingredients & Drug Interactions

by BulkSupplements.com

Astaxanthin Softgels 12 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Astaxanthin Softgels 12 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Astaxanthin Softgels 12 mg is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 673 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Astaxanthin Softgels 12 mg by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Astaxanthin Softgels 12 mg by BulkSupplements.com — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Astaxanthin Softgels 12 mg by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains one active ingredient: 12 mg of astaxanthin, a pigment from algae and seafood known for its antioxidant properties. The remaining contents are inactive ingredients — sunflower oil, bovine gelatin, and water — which serve as the capsule shell and carrier.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Astaxanthin product and its label doesn't state a use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish that astaxanthin is effective for the conditions listed in the product facts — age-related cognitive decline, macular degeneration (AMD), aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome all carry a rating of insufficient reliable evidence. That means we simply don't have enough solid data yet to say whether it works for these uses.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, but long-term safety data are limited. The most common side effects from oral use are abdominal pain, diarrhea, and red-colored stools.

At the 6 mg dose, a small number of trial participants reported increased bowel movements and red stools; at much higher doses (40 mg daily), severe stomach pain has occurred in a small number of patients. The safety data advises against use during pregnancy and while breastfeeding due to insufficient information.

If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 674 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you take medications broken down by your liver through CYP3A4 or CYP2B6 enzymes — common types include certain cholesterol medications, immunosuppressants, cancer drugs, some antidepressants, and antiretrovirals. Astaxanthin may theoretically speed up how your liver clears these drugs, potentially lowering their levels, though this effect has only been shown in lab studies so far.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Astaxanthin is a single-ingredient antioxidant supplement that appears generally well tolerated short-term, though long-term safety isn't well established. Its main concern is the potential to affect how your liver processes certain medications — a theoretical risk based on lab findings that hasn't been proven in people yet.

Before starting it, check your medications with your own doctor or pharmacist, especially if you take drugs metabolized through CYP3A4 or CYP2B6. Avoid this product if you're pregnant or breastfeeding unless your healthcare provider advises otherwise.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Astaxanthin Softgels 12 mg, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X003FJPK5J
Net contents 180 Softgel(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 312651
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Astaxanthin Softgels 12 mg by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
180
UPC/BARCODE
X003FJPK5J
IngredientAmount% DV
Astaxanthin12 mg--

Other ingredients: Sunflower Oil, Bovine Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Astaxanthin softgels 12mg per serving

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1 softgel daily, or as directed by a physician.

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Storage

Store in a dry, cool place.

Formulation

Free of: Added sugar, dairy, yeast, soy, gluten.

General Statements

New Scan me

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See for yourself

Astaxanthin Softgels 12 mg by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Astaxanthin Softgels 12 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Astaxanthin Softgels 12 mg by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container180 Amounts shown are per serving.

Astaxanthin

Interacts with
673 drugs
12 mg per serving

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Astaxanthin monograph & interactions

Other (inactive) ingredients: Sunflower Oil, Bovine Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Astaxanthin Softgels 12 mg by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Astaxanthin Softgels 12 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
673Drugs
673 Moderate

Ingredients driving the most interactions

Astaxanthin 673

Individual Drug Interactions

The ingredients in Astaxanthin Softgels 12 mg interact with 673 drugs. Click any drug to see the details.

1 of the 1 ingredient in Astaxanthin Softgels 12 mg interact with drugs. Each result below shows which ingredient is responsible. Astaxanthin

Each ingredient & the kinds of drugs it affects

For each ingredient in Astaxanthin Softgels 12 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Astaxanthin2 drug types · 673 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Astaxanthin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Astaxanthin Softgels 12 mg, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Astaxanthin Softgels 12 mg by BulkSupplements.com: Common Questions

Does Astaxanthin Softgels 12 mg by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Astaxanthin Softgels 12 mg has a known interaction with 673 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Astaxanthin Softgels 12 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is astaxanthin and what does it do?
Astaxanthin is a reddish pigment and antioxidant found in algae and seafood. While it's marketed for several age-related and performance concerns, the data we have doesn't yet establish whether it's actually effective for any of them.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against it — there isn't enough information to know it's safe during pregnancy or breastfeeding. Talk with your doctor or pharmacist before taking this product in either situation.
What side effects might I experience?
Most commonly, abdominal pain, diarrhea, and red-colored stools. A small number of people on lower doses reported increased bowel movements; higher doses have caused severe stomach pain in rare cases.
Is this safe to take long-term?
It's generally well tolerated in the studies we have, but long-term safety data are limited. That means we simply don't have enough information about what happens if you take it for months or years.
Does it contain any fillers or additives?
The softgel itself is made from bovine gelatin, sunflower oil, and water — these are inactive ingredients that form the capsule. The active ingredient is the astaxanthin alone.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Astaxanthin Softgels 12 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Astaxanthin Softgels 12 mg label
Go deeper

The Full Monographs Behind Astaxanthin Softgels 12 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astaxanthin

Interacts with 673 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Astaxanthin Softgels 12 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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