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Dietary supplement

Astaxanthin Softgels 12 mg Ingredients & Drug Interactions

by BulkSupplements.com

Astaxanthin Softgels 12 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Astaxanthin Softgels 12 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Astaxanthin Softgels 12 mg is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Astaxanthin Softgels 12 mg by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Astaxanthin Softgels 12 mg by BulkSupplements.com — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Astaxanthin Softgels 12 mg by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains one active ingredient: astaxanthin, a carotenoid pigment (a type of plant compound with antioxidant properties) at 12 mg per capsule. The remaining ingredients are sunflower oil, bovine gelatin, and water — these are inert carriers and the capsule shell that help deliver the astaxanthin.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Astaxanthin product and its label doesn't state a use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for astaxanthin's effectiveness is insufficient to rate across all the uses we have data for, including age-related cognitive decline, macular degeneration (age-related vision loss), aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome. That means studies to date haven't provided enough reliable information to say whether it works for these purposes.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in the studies we have, but long-term safety data are limited — we don't have much information on what happens with years of use. The most common side effects reported are abdominal pain, diarrhea, and red-colored stools.

At the 12 mg dose in this product, side effects appear uncommon, though at higher doses (40 mg daily) severe stomach pain has been reported in a small number of people. Pregnancy and breastfeeding: There isn't enough safety data to know whether astaxanthin is safe during pregnancy or while breastfeeding.

The safety data advises against use in both situations. Talk with your doctor or pharmacist for personalized guidance if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting astaxanthin, check any medications that are processed by your liver's CYP3A4 or CYP2B6 enzymes — the product may theoretically lower their blood levels. Examples include many statins, some blood pressure medications, and certain antiretrovirals, among others.

Use the medication checker on this page to verify your specific drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Astaxanthin is generally well tolerated, but we don't yet know if it actually works for the conditions it's marketed for. If you take medications metabolized through your liver's CYP3A4 or CYP2B6 pathways, check them against our interaction tool before you start — the theoretical risk is unclear in real patients.

Avoid during pregnancy and breastfeeding. Your pharmacist can help you weigh whether this product fits your needs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Astaxanthin Softgels 12 mg, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X003FJPK5J
Net contents 180 Softgel(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 312651
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Astaxanthin Softgels 12 mg by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
180
UPC/BARCODE
X003FJPK5J
IngredientAmount% DV
Astaxanthin12 mg--

Other ingredients: Sunflower Oil, Bovine Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Astaxanthin softgels 12mg per serving

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1 softgel daily, or as directed by a physician.

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Storage

Store in a dry, cool place.

Formulation

Free of: Added sugar, dairy, yeast, soy, gluten.

General Statements

New Scan me

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Astaxanthin Softgels 12 mg by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Astaxanthin Softgels 12 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Astaxanthin Softgels 12 mg by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container180 Amounts shown are per serving.

Astaxanthin

Interacts with
671 drugs
12 mg per serving

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Astaxanthin monograph & interactions

Other (inactive) ingredients: Sunflower Oil, Bovine Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Astaxanthin Softgels 12 mg by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Astaxanthin Softgels 12 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

Astaxanthin 671

Individual Drug Interactions

The ingredients in Astaxanthin Softgels 12 mg interact with 671 drugs. Click any drug to see the details.

1 of the 1 ingredient in Astaxanthin Softgels 12 mg interact with drugs. Each result below shows which ingredient is responsible. Astaxanthin

Each ingredient & the kinds of drugs it affects

For each ingredient in Astaxanthin Softgels 12 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Astaxanthin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Astaxanthin Softgels 12 mg, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Astaxanthin Softgels 12 mg by BulkSupplements.com: Common Questions

Does Astaxanthin Softgels 12 mg by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Astaxanthin Softgels 12 mg has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Astaxanthin Softgels 12 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will astaxanthin give me red stools?
Red fecal color has been reported, especially at higher doses, but it's not harmful — it's just the astaxanthin pigment passing through. At the 12 mg dose in this product, it's uncommon.
Can I take this while pregnant or breastfeeding?
There isn't enough safety data to know either way. The safety data advises against it during both pregnancy and breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you in those situations.
Does astaxanthin actually work for aging skin or memory?
The evidence we have is insufficient to say. Studies haven't provided reliable information yet on whether it works for aging skin, cognitive decline, or other uses this product is marketed for.
What are the side effects?
Astaxanthin is generally well tolerated. The most common side effects are abdominal pain, diarrhea, and red-colored stools — these are uncommon at the 12 mg dose. Long-term safety data are limited.
Why might my liver medications not work as well on this?
Lab research shows astaxanthin may speed up how your liver breaks down certain drugs (those processed by CYP3A4 and CYP2B6), which could lower their blood levels. This hasn't been confirmed in real patients yet, but it's why we ask you to check your medications first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Astaxanthin Softgels 12 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Astaxanthin Softgels 12 mg label
Go deeper

The Full Monographs Behind Astaxanthin Softgels 12 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Astaxanthin Softgels 12 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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