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Dietary supplement

Astaxanthin 12 mg Ingredients & Drug Interactions

by Jarrow Formulas

Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Astaxanthin 12 mg is a dietary supplement by Jarrow Formulas with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Astaxanthin 12 mg by Jarrow Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: astaxanthin 12 mg per softgel. Astaxanthin is a natural red pigment found in algae and seafood.

The softgel capsule also contains several inactive ingredients — safflower oil, bovine gelatin, glycerin, water, mixed tocopherols, olive oil, and rosemary extract — which help deliver and preserve the astaxanthin.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune, skin, and eye health support.
  • We looked for evidence on: Age-related macular degeneration (AMD), Aging skin, Dry eye, Sunburn, immune function, antioxidant protection.
  • The closest evidence on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Dry eye, Sunburn.

The evidence we hold doesn't establish that astaxanthin works reliably for any of the uses listed on the label — age-related cognitive decline, macular degeneration, aging skin, Alzheimer disease, athletic performance, or carpal tunnel syndrome. All of these carry a rating of insufficient reliable evidence to rate, meaning the research so far hasn't been robust enough to draw firm conclusions.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects reported in trials include abdominal pain, diarrhea, and red fecal color (a harmless color change).

Higher doses (40 mg daily) have caused severe stomach pain in a small number of trial participants. Not enough safety data exists for pregnancy or breastfeeding — the facts advise against use in both.

Talk with your doctor or pharmacist if you're pregnant, nursing, or planning to become pregnant before taking this supplement.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Astaxanthin 12 mg, check any medications you take that are processed by your liver through the CYP3A4 or CYP2B6 pathways — astaxanthin may theoretically lower their levels. Use the medication checker on this page to verify your prescriptions, as the effect hasn't been confirmed in humans yet.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Astaxanthin may appeal to you if you're exploring antioxidant supplements, but evidence for its effectiveness in the listed conditions isn't established in the data we have. If you take any medications metabolized by liver enzymes CYP3A4 or CYP2B6, check them with the tool below before starting — the interaction risk is theoretical but spans many common drugs.

Talk with your pharmacist about your full medication list and whether this is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Astaxanthin 12 mg, straight from the product label.

Brand Jarrow Formulas
Barcode (UPC) 790011202127
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 321949
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Astaxanthin 12 mg by Jarrow Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
UPC/BARCODE
790011202127
IngredientAmount% DV
Astaxanthin12 mg--

Other ingredients: Safflower Oil, Bovine Gelatin, Glycerin, Water, Mixed Tocopherols, Olive Oil, Rosemary Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Adults take 1 softgel once a day, preferably with a fat-containing meal or as directed by your qualified healthcare professional.

Formula

Jarrow Formulas Astaxanthin, featuring AstaPure astaxanthin is naturally derived from the cultivation of a unique Haematococcus pluvialis microalgae strain. Clinical studies have demonstrated that astaxanthin supports immune, skin, and eye health.

AstaPure Algal antioxidant

Precautions

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication or have a medical condition; if adverse reactions occur, discontinue use.

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication or have a medical condition; if adverse reactions occur, discontinue use. Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

AstaPure is a registered trademark of Algatechnologies Ltd.

Copyright 2022 Jarrow Formulas

Formulation

Supports immune, skin, and eye health

Non-GMO Gluten free

No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame.

FDA Statement of Identity

Dietary Supplement

General Statements

Immune support

See for yourself

Astaxanthin 12 mg by Jarrow Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Astaxanthin 12 mg by Jarrow Formulas

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Astaxanthin

Interacts with
671 drugs
12 mg per serving Form: Haematococcus pluvialis

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Astaxanthin monograph & interactions

Other (inactive) ingredients: Safflower Oil, Bovine Gelatin, Glycerin, Water, Mixed Tocopherols, Olive Oil, Rosemary Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Astaxanthin 12 mg by Jarrow Formulas Drug Interactions

Want to check YOUR meds against Astaxanthin 12 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Astaxanthin 12 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Astaxanthin 12 mg, from the product label.

Jarrow Formulas

See all Jarrow Formulas products
Name
Jarrow Formulas, Inc.
City
Sherman Oaks
State
CA
ZipCode
91403
Phone Number
1-866-459-4154
Web Address
www.Jarrow.com
Pharmacist Counseling Corner

Astaxanthin 12 mg by Jarrow Formulas: Common Questions

Does Astaxanthin 12 mg by Jarrow Formulas interact with any medications?
Yes. Based on its ingredients, Astaxanthin 12 mg has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Astaxanthin 12 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take astaxanthin if I'm pregnant or breastfeeding?
The safety data aren't available to know either way, so it's best to avoid it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist for personalized advice.
What side effects might I experience?
Most common side effects are abdominal pain, diarrhea, and red fecal color — which is harmless, just a color change from the pigment. A small number of people on higher doses reported severe stomach pain. Astaxanthin seems generally well tolerated, but long-term safety data are limited.
Does astaxanthin actually work for aging skin or memory?
We don't have enough reliable evidence in our data to say it works for aging skin, memory, macular degeneration, or the other uses listed. The research so far hasn't been robust enough to draw firm conclusions.
What is astaxanthin?
It's a natural red pigment found in algae and seafood. It's an antioxidant, meaning it's thought to help protect cells from damage, but evidence for specific health benefits isn't established in the data we hold.
Will this supplement interfere with my blood pressure or heart medications?
Astaxanthin may theoretically affect how your liver breaks down certain medications, including some used for heart and blood pressure — but this effect hasn't been confirmed in humans yet. Check your exact prescriptions with the medication checker on this page before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Astaxanthin 12 mg label
Sources

Sources & How We Checked

Astaxanthin 12 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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