Bacchus By Chaos and Pain Overview & Drug Interactions

Phenethylamine (PEA) is a monoamine alkaloid present in various sources, including plants, bacteria, fungi, and animals, including humans. It is also found in certain foods like chocolate and eggs. This compound is synthesized in the body through the decarboxylation of the amino acid L-phenylalanine. Within the central nervous system, PEA serves as both a neuromodulator and neurotransmitter, playing a crucial role in neuronal signaling. Phenethylamine is available as a dietary supplement and is used for potential cognitive and mood-enhancing effects, although further research is needed to fully understand its effects in these regards.

Rhodiola is a type of plant native to the Arctic regions of Europe and Asia. It is also known as "golden root" or "arctic root." The roots and rhizomes of Rhodiola are commonly used in dietary supplements for their purported effects as an 'adaptogen', which are used to improve physical and mental performance, reduce fatigue, and enhance the ability to cope with stress. Rhodiola is believed to work by increasing the production of certain chemicals in the brain (e.g., serotonin, dopamine, and norepinephrine) that are involved in mood and energy regulation. Rhodiola supplements are often standardized to a specific amount of their rosavin and salidroside content.

Theanine, often referred to as L-theanine as that is the predominant isomer of theanine, is an amino acid commonly found in tea leaves, particularly in green tea. It is purported to increase levels of GABA, serotonin, and dopamine in the brain, which can help to reduce stress and anxiety. L-theanine may also promote a sense of calm and improve overall well-being. Some studies have also suggested that it may improve cognitive function, although more research is needed. Most reported drug interactions with theanine are due to its sedative effects.

Hordenine is a naturally occurring alkaloid found in various plants, including barley and cacti. It is structurally related to epinephrine and ephedrine and gets its name from the Hordeum genus of barley, from which it was first isolated. Hordenine has been marketed as a dietary supplement with claims of boosting energy and athletic performance, but there is limited scientific evidence to support these claims. Some studies suggest that it may have properties as a stimulant, but further research is needed to confirm its effects and safety.

5-HTP, or 5-hydroxytryptophan, is a naturally-occurring amino acid and a precursor to the neurotransmitter serotonin. It is used as a dietary supplement to improve mood and help with anxiety, sleep disorders, and other conditions. It is also sometimes used in combination with other medications to treat migraines and fibromyalgia. The 5-HTP found in supplements is most often obtained from the seeds of the tropical shrub Griffonia simplicifolia