Interactions on record — worth a quick check against your medications. Based on 5 of 8 ingredients. Check your meds →
Dietary supplement

BCAA+G RELOAD Lemonade Flavored Ingredients & Drug Interactions

by MRM Nutrition

BCAA+G RELOAD Lemonade Flavored label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking BCAA+G RELOAD Lemonade Flavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

BCAA+G RELOAD Lemonade Flavored is a dietary supplement by MRM Nutrition with 8 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 282 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B6, Sodium, L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against BCAA+G RELOAD Lemonade Flavored by MRM Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with BCAA+G RELOAD Lemonade Flavored by MRM Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of BCAA+G RELOAD Lemonade Flavored by MRM Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 8 of its 8 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

BCAA+G RELOAD contains 8 ingredients, with five active: L-glutamine, vitamin B6, sodium, and three branched-chain amino acids—L-leucine, L-isoleucine, and L-valine (often called BCAAs). It also includes CarnoSyn (a form of beta-alanine) and betaine anhydrous.

The remaining ingredients are inactive flavor and texture components: lemonade flavoring, citric acid, stevia leaf extract, sea salt, silicon dioxide, and monk fruit extract.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle recovery and exercise performance.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle breakdown, Exercise-induced muscle damage, muscle soreness, strength gains, post-workout fatigue.
  • The strongest evidence on file: Beta-alanine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Glutamine is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle damage.

The evidence for this product's ingredients is mixed. L-glutamine is effective for sickle cell disease and possibly effective for HIV/AIDS-related wasting and recovery from surgery or critical illness.

Vitamin B6 is effective for sideroblastic anemia and pyridoxine-dependent epilepsy, and possibly effective for pregnancy-related nausea and high homocysteine levels. CarnoSyn (beta-alanine) is possibly effective for athletic and physical performance.

Betaine anhydrous is effective for homocysteinuria and possibly effective for high homocysteine. The branched-chain amino acids themselves, and betaine's use for other conditions like nonalcoholic fatty liver disease or depression, lack established evidence in our data.

The evidence, ingredient by ingredient Glutamine Vitamin B6 Sodium Beta-alanine Betaine Anhydrous

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is rated likely safe in pregnancy and lactation, but it's generally well tolerated in healthy adults and commonly causes bloating, gas, constipation, nausea, or diarrhea—particularly at higher doses. People with kidney or liver disease need medical supervision.

Vitamin B6 is likely safe in pregnancy and lactation at standard doses but can damage nerves (peripheral neuropathy) with very high doses over time—doses above 1,000 mg daily carry the most risk. Sodium is likely safe in normal dietary amounts but possibly unsafe in excess during pregnancy and lactation; too much is linked to high blood pressure and heart strain.

CarnoSyn (beta-alanine) commonly causes harmless skin tingling and flushing and should be avoided in pregnancy and breastfeeding due to insufficient safety data. Betaine anhydrous is generally well tolerated but may cause body odor, diarrhea, nausea, or gastrointestinal upset; avoid in pregnancy and breastfeeding unless your doctor advises otherwise.

Side effects, ingredient by ingredient Glutamine Vitamin B6 Sodium Beta-alanine Betaine Anhydrous

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 5 matched ingredients can interact with medications — Glutamine, Vitamin B6, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications; lithium; Parkinson's medications.
  • For scale: 282 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking BCAA+G RELOAD, check with your pharmacist if you take anticonvulsants (seizure medications), blood pressure medications, amiodarone (a heart rhythm drug), phenobarbital or phenytoin specifically, lithium, levodopa, corticosteroids, didanosine, or any sodium-containing medications. The most serious concern is with lithium—sodium changes can cause dangerous shifts in lithium levels.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is aimed at athletic performance and recovery, with some ingredients supported by evidence for those uses. However, the multiple drug interactions—especially with anticonvulsants, blood pressure medications, and lithium—mean you need to check your medications before you start.

If you take any prescription drugs, talk to your pharmacist or doctor with this product in hand.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about BCAA+G RELOAD Lemonade Flavored, straight from the product label.

Brand MRM Nutrition
Barcode (UPC) 60949271037
Net contents 29.6 Ounce(s); 840 Gram(s)
Market status On market
Date entered into DSLD Dec 21, 2024
DSLD ID 319061
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for BCAA+G RELOAD Lemonade Flavored by MRM Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
12.5 Gram(s)
Maximum serving Sizes:
12.5 Gram(s)
Servings per container
67
UPC/BARCODE
60949271037
IngredientAmount% DV
Calories15 Calorie(s)--
Total Carbohydrates4 Gram(s)1%
L-Glutamine2000 mg--
Vitamin B62 mg120%
Sodium70 mg3%
L-Leucine3000 mg--
L-Isoleucine1000 mg--
L-Valine1000 mg--
Added Sugars1 Gram(s)2%
Total Sugars1 Gram(s)--
CarnoSyn750 mg--
Betaine Anhydrous750 mg--

Other ingredients: Lemonade Flavor, Natural, Citric Acid, Stevia Leaf Extract, Pure Ocean Sea Salt, Silicon Dioxide, Monk Fruit Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: Add 2 slightly rounded scoops to 10-16 oz of water and shake or blend well.

Formulation

Supports muscle recovery Reduces fatigue & muscle soreness Provides increases in strength & power

GF (Gluten-free)

Certified vegan Vegan.org

Post-workout recovery

Contains no added milk, egg, peanut, tree nut, fish, shellfish, soy, wheat, gluten or yeast ingredients.

Formula

Keto & low carb diet friendly

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Made from recycled materials

FDA Statement of Identity

Dietary Supplement

Precautions

This product is manufactured in a facility that processes other products that contain milk or egg.

Warning: Due to the beta-alanine content this product may cause a harmless tingling or flushing sensation.

Brand IP Statement(s)

CarnoSyn Carnosine Synthesizer Natural Alternatives International (NAI) is the owner of patents as listed on www.carnosyn.com and registered trademark CarnoSyn.

Pure Ocean is a registered trademark of SaltWorks, Inc.

Seals/Symbols

Certified vegan Vegan.org

Storage

This product is packaged by weight, not volume. Like many powdered food/supplement products the size of this container does not necessarily depict the actual amount of product within. Unavoidable and sometimes significant product settling may occur during shipping and handling.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

BCAA+G RELOAD Lemonade Flavored by MRM Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

BCAA+G RELOAD Lemonade Flavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in BCAA+G RELOAD Lemonade Flavored by MRM Nutrition

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size12.5 Gram(s) Dosage formPowder Servings per container67 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
2000 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Vitamin B6

Interacts with
210 drugs
2 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Sodium

Interacts with
205 drugs
70 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

L-Leucine

3000 mg per serving

L-Isoleucine

1000 mg per serving

L-Valine

1000 mg per serving

CarnoSyn

No known
interactions
750 mg per serving Form: Beta-Alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...

CarnoSyn monograph & interactions

Betaine Anhydrous

No known
interactions
750 mg per serving

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and a...

Betaine Anhydrous monograph & interactions

Other (inactive) ingredients: Lemonade Flavor, Natural, Citric Acid, Stevia Leaf Extract, Pure Ocean Sea Salt, Silicon Dioxide, Monk Fruit Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

BCAA+G RELOAD Lemonade Flavored by MRM Nutrition Drug Interactions

Want to check YOUR meds against BCAA+G RELOAD Lemonade Flavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
282Drugs
277 Moderate 5 Minor

Ingredients driving the most interactions

Vitamin B6 210
Sodium 205
L-Glutamine 50

Individual Drug Interactions

The ingredients in BCAA+G RELOAD Lemonade Flavored interact with 282 drugs. Click any drug to see the details.

3 of the 8 ingredients in BCAA+G RELOAD Lemonade Flavored interact with drugs. Each result below shows which ingredient is responsible. Vitamin B6 Sodium L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in BCAA+G RELOAD Lemonade Flavored with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for BCAA+G RELOAD Lemonade Flavored, from the product label.

MRM Nutrition

See all MRM Nutrition products
Name
MRM
Street Address
2665 Vista Pacific Dr
City
Oceanside
State
CA
ZipCode
92056
Phone Number
1-800-948-6296
Web Address
www.mrmnutrition.com
Pharmacist Counseling Corner

BCAA+G RELOAD Lemonade Flavored by MRM Nutrition: Common Questions

Does BCAA+G RELOAD Lemonade Flavored by MRM Nutrition interact with any medications?
Yes. Based on its ingredients, BCAA+G RELOAD Lemonade Flavored has a known interaction with 282 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
BCAA+G RELOAD Lemonade Flavored contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
L-glutamine and vitamin B6 are likely safe at normal doses, but the sodium content and other ingredients are possibly unsafe in pregnancy or lactation at higher intakes. CarnoSyn and betaine anhydrous lack enough safety data to use during pregnancy or while breastfeeding. Talk to your doctor or midwife before starting.
Will this cause the tingling I've heard about?
Yes, CarnoSyn (beta-alanine) in this product commonly causes paresthesia—a pins-and-needles feeling, usually starting on the scalp within 20 minutes and spreading across the body for about an hour. This is harmless but can feel uncomfortable. Dose and frequency affect how intense it is.
What's glutamine actually for in this product?
L-glutamine is included for muscle recovery and immune support. It's effective for sickle cell disease and possibly helpful for recovery after surgery or critical illness. In healthy people doing exercise, the evidence isn't as clear, but it's often used for post-workout recovery.
Is this formula high in sodium?
The product contains sodium, likely from sea salt. If you have high blood pressure, are taking blood pressure medications, or take lithium, you need to check how much sodium is in each serving and discuss it with your pharmacist or doctor, since excess sodium can interfere with those medications.
What's the beta-alanine (CarnoSyn) for?
Beta-alanine is possibly effective for athletic and physical performance. It won't cause muscle growth on its own but may help with endurance and strength when combined with training.
Can I take this long-term?
Beta-alanine safety hasn't been studied at high doses over the long term, so the facts don't tell us how safe very long-term use is. L-glutamine is well tolerated in healthy adults, but betaine anhydrous and vitamin B6 should be discussed with your doctor if you're planning ongoing use at high doses.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if BCAA+G RELOAD Lemonade Flavored is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

BCAA+G RELOAD Lemonade Flavored label
Go deeper

The Full Monographs Behind BCAA+G RELOAD Lemonade Flavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph → Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Beta-alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...

Read the full Beta-alanine monograph → Herb & supplement monograph

Betaine Anhydrous

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and as a prescription medicine for a rare gen...

Read the full Betaine Anhydrous monograph →
Sources

Sources & How We Checked

BCAA+G RELOAD Lemonade Flavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 105 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  17. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
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Sodium 38 references
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Beta-alanine 13 references
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  2. Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
  3. Bellinger PM, Minahan CL. The effect of ß-alanine supplementation on cycling time trials of different length. Eur J Sport Sci 2016;16(7):829-36.
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See these in context on the Beta-alanine monograph →

Betaine Anhydrous 11 references
  1. Cystadane (betaine anhydrous for oral solution) Package insert. Orphan Medical, Inc. Minnetonka, MN. November 2005.
  2. Abdelmalek MF, Angulo P, Jorgensen RA, et al. Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Am J Gastroenterol 2001;96:2711-7.. PubMed
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See these in context on the Betaine Anhydrous monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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